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Let me be clear — antibodies declining after COVID infection is completely normal part of immunity— antibodies against any former infection are not gone forever - its “recipe” for building specific antibodies are archived in MEMORY B CELLS of your body for retrieval later. 🧵
2) thus, it makes it very unlikely for reinfection even if your coronavirus antibodies drop later. Here is a good article explaining it by @apoorva_nyc.
3) That said, @PeterHotez says ““I’m not saying (reinfection) can’t happen. But from what I’ve seen so far, that would be an uncommon phenomenon,” said Dr. Peter Hotez, the dean of the National School of Tropical Medicine at Baylor College of Medicine. ➡️And that is very fair.
4) background- “People infected typically produce immune molecules called antibodies. Several teams have recently reported that levels of the antibodies decline in 2-3 months. But a drop in antibodies is perfectly normal after an acute infection subsides, said @michaelmina_lab.”
5) And this has even misunderstood by many regular doctors. “Many clinicians are “scratching their heads saying, ‘What an extraordinarily odd virus that it’s not leading to robust immunity,’ but they’re totally wrong. It doesn’t get more textbook than this” says @michaelmina_lab
6) “None of this is really surprising from a biological point of view,” said @florian_krammer, an immunologist.

@michaelmina_lab agreed. “This is a famous dynamic of how antibodies develop after infection: They go very, very high, and then they come back down”
7) Other experts who research antibodies also agree that antibodies declining is normal, including @SCOTTeHENSLEY and @MackayIM. Here is the source of the original top figure.
8) I’m trying to be thorough and clear as possible on this for a reason — there are anti-vaxxer misinformation and other odd disinformation out there that uses the bad claim “antibody drop means vaccines won’t work” to dangerously tell people not to vaccinate. It’s nonsense!!!
9) This is why I’m vehemently putting my foot down on this. My colleagues and I and @FAScientists monitor coronavirus misinformation on a daily basis and it’s quite dangerous out there. Sad thing is anti vaccine misinformation is getting worse. Much worse. nature.com/articles/s4158…
10) thus, please read @apoorva_nyc’s detailed and thorough reporting on this. We need to stop the nonsense, and see how anti vaxxers can the confusion it against vaccines down the road. Thanks again @michaelmina_lab @florian_krammer @PeterHotez and others. nytimes.com/2020/07/22/hea…
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