New study out on the mRNA-1273 vaccine in @NEJM and its more good news.
Its a study in non-human primates -- a challenge study where primates were vaccinated, then challenged with the virus.
nejm.org/doi/full/10.10…
So what did they find?
As I said, good news.
Short thread
Its a study in non-human primates -- a challenge study where primates were vaccinated, then challenged with the virus.
nejm.org/doi/full/10.10…
So what did they find?
As I said, good news.
Short thread
24 rhesus macques were innoculated with one of two doses of the vaccine
They all developed (especially at the higher doses) neutralizing antibodies
And developed t-cell responses.
More robust in the higher dose
But there's more!
2/3
They all developed (especially at the higher doses) neutralizing antibodies
And developed t-cell responses.
More robust in the higher dose
But there's more!
2/3
When subsequently challenged by SARS-CoV2, small number of macques had any detectable virus
None developed severe illness
More evidence that m-RNA vaccines will likely work
We obviously still need to await phase 3 trials
But I'm optimistic we will have a vaccine in 2021
Fin
None developed severe illness
More evidence that m-RNA vaccines will likely work
We obviously still need to await phase 3 trials
But I'm optimistic we will have a vaccine in 2021
Fin
