#neurotwitter #tweetorial
ncbi.nlm.nih.gov/pubmed/18184149
A multicenter study from Italy randomized 193 people to deferred treatment after second seizure. Recurrence risks were 18%,28%,41%,51% at 3,6,12,24 months after first sz
Recurrence risk was 26%,39%,51%,52% at 6m, 2y,5y,8y.
ncbi.nlm.nih.gov/pubmed/15950714
ncbi.nlm.nih.gov/pubmed/9459646
ncbi.nlm.nih.gov/pubmed/10939563
Epileptiform abnormalities on eeg and symptomatic cause (for example brain injury, malformation, etc) routinely are noted to increase recurrence risk
The AAN guideline summarized data that shows likelihood of long term remission does not improve by treating early.
ncbi.nlm.nih.gov/pubmed/25901057