Had a realization about quiet heart sounds that came about a decade late.
Short thread.
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Ok.
S1 and S2 happen when pressure gradients snap them shut. Right-sided cardiac pressures and thus valve-closing pressure gradients are lower, this P2 is quieter than A2.
And if you get pulmonary hypertension, P2 gets louder.
A bit more from UpToDate:
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What about hypOtension? If you’re septic or bleeding or in cardiogenic shock, the lower pressure gradients should translate to quieter sounds.
Thus, quiet heart sounds in this setting are probably less discerning for pericardial fluid.
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I couldn’t find anything describing frequency or test characteristics on a few search attempts. If anyone know of any studies, please comment!
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Op report: “gangrenous cholecystitis with extremely friable tissue. Purulent drainage with manipulation of gallbladder.”
I've seen this many times.
Thread
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Like any test, RUQUS is not perfect in detecting cholecystitis.
A systematic review in 2012 put pooled sensitivity at 81%, but as you see in plot of included studies, there's heterogeneity, with sensitivity as low as 50% in some studies.
Press the hypothenar edge of your hand firmly against your own ribcage. You're gonna keep it there the whole time while you say some stuff and feel the amount of vibrations transmitted.
Let's go.
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Experiment # 1:
Compare the amount of fremitus/vibration when you say:
ninety-nine
noy-noy-noy
one-two-three
Feel free to repeat a couple times.
Did any of them cause more vibration than others?
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Experiment #2
Pick any one of the three chants above.
Compare the amount of vibrations when you say the phrase in the lowest (deepest) voice you can muster... vs. a high-pitched (e.g. falsetto-y) voice.
Can upper GI bleeding cause hyperkalemia in predisposed people?
I feel like I’ve gotten that vibe from a couple patients. I can’t find any reports from others.. but I can think of a mechanism...
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Blood contains a lot of protein.
When a significant amount of it is introduced into the proximal GI lumen (and some of it absorbed), it can elevate your BUN, or trigger hepatic encephalopathy.
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The concentration of potassium in RBCs is ~100 mMol, meaning 100 mEq/L. If you start at a hematocrit of 40 and bleed 20% of your blood volume into your stomach...
That’s ~1 liter blood = 400 cc of red cells = 40 mEq of potassium.
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