Your Coronavirus Test Is Positive. Maybe It Shouldn’t Be. nytimes.com/2020/08/29/hea…
The PCR test amplifies genetic matter from the virus in cycles; the fewer cycles required, the greater the amount of virus, or viral load, in the sample. The greater the viral load, the more likely the patient is to be contagious.
This number of amplification cycles needed to find the virus, called the cycle threshold, is never included in the results sent to doctors and coronavirus patients, although it could tell them how infectious the patients are.
One solution would be to adjust the cycle threshold used now to decide that a patient is infected. Most tests set the limit at 40, a few at 37. This means that you are positive for the coronavirus if the test process required up to 40 cycles, or 37, to detect the virus.
Tests with thresholds so high may detect not just live virus but also genetic fragments, leftovers from infection that pose no particular risk — akin to finding a hair in a room long after a person has left, Dr. Mina said.
Any test with a cycle threshold above 35 is too sensitive, agreed Juliet Morrison, a virologist at the University of California, Riverside. “I’m shocked that people would think that 40 could represent a positive,” she said.
A more reasonable cutoff would be 30 to 35, she added. Dr. Mina said he would set the figure at 30, or even less. Those changes would mean the amount of genetic material in a patient’s sample would have to be 100-fold to 1,000-fold that of the current standard for the test
Dr. Jha said he had thought of the PCR test as a problem because it cannot scale to the volume, frequency or speed of tests needed. “But what I am realizing is that a really substantial part of the problem is that we’re not even testing the people who we need to be testing,”
But that problem is easily solved, Dr. Mina said: “Test them again, six hours later or 15 hours later or whatever,” he said. A rapid test would find these patients quickly, even if it were less sensitive, because their viral loads would quickly rise.
PCR tests still have a role, he and other experts said. For example, their sensitivity is an asset when identifying newly infected people to enroll in clinical trials of drugs.
But with 20 percent or more of people testing positive for the virus in some parts of the country, Dr. Mina and other researchers are questioning the use of PCR tests as a frontline diagnostic tool
Highly sensitive PCR tests seemed like the best option for tracking the coronavirus at the start of the pandemic. But for the outbreaks raging now, he said, what’s needed are coronavirus tests that are fast, cheap and abundant enough to frequently test everyone who needs it.
“It might not catch every last one of the transmitting people, but it sure will catch the most transmissible people, including the superspreaders,” Dr. Mina said. “That alone would drive epidemics practically to zero.”

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More from @NavroopSingh_

9 Nov
Verifiable records of his birthday celebration shows 7th March 1973. Dat makes him Meen Rashi & Vrischik Lagna. Chadra & Buddh together in 5th shows he is always at something in his mind & very sharp and intelligent brain. But Angkarak Yog in 2nd house in Rashi & Navamsha Chart.
Angkarak Yog in 2nd shows temper issues, harsh speech & abusive language as well (his ex employees have detailed his temper issues). Also mangal is 6th lord sitting with Rahu in Dhan sthan in Rashi Chart & Labh Sthan in Navamsha shows he will have many enemies who will cause harm
Also his Guru is Debilitated & Mercury the 8th & 11th lord is also badly hammered being debilitated thus causing him to be target secret sinister plots behind his back. Shani is his marak grah is now in his marak sthana causing him this pain. Mangal his 6th lord is Vakri as well.
Read 6 tweets
6 Nov
Narendra Modi has developed excellent relationship with USA contrary to Sonia Gandhi’s UPA who instigated diplomatic spat on Devyani Khobragade with USA & in fear of China refused to sign up military agreements with USA like DTTI. AK Antony was on record saying it.
It is Narendra Modi who signed DTTI, LEMOA, COMCASA, ISA & BECA. It is Modi who has firmed up stand towards China & taken the battle head on with QUAD. US Congress has also passed ba-partisan laws on giving high end military technology to India.
All this in last 5 years what Congress cud not do in 60 years.

Also American foreign policy is institutionalised unlike India where regime change can change whole dynamics it is foolish to believe Biden would bring substantive change to Indo-US Partnerships.
Read 8 tweets
4 Nov
Saw this coming. Though internally hoping for a Trump Win !
My astrology on Trump. Had stated the weakness in Trump Chart. Never predicted landslide win on basis of his chart (though i wish for same)
Difference between 2016 clear win & 2020 chaos is Trump is Simha Lagna with Magha Nakshatra just like USA and Surya his Lagna Lord is debilitated & dispositor of his node Shukra is also debilitated & running a Marak MD of Guru unlike 10th Rahu which gave him power in 2016.
Read 5 tweets
28 Oct
Anti CAA stir that led to riots would be covered by definition of terrorist act: Delhi Court - oneindia.com/amphtml/india/…
Additional Sessions Judge, Amitabh Rawat said, the entire conspiracy beginning from December 2019 of intentionally blocking roads and causing disrupting of the supplies of services, resulting in violence with various means and then leading to the February incident with the focus
being targeted at blocking of roads at mixed population areas and creating panic and attack on the police personnel with facade of women protesters in front and leading to riots would be covered by the definition of a terrorist act.
Read 5 tweets
26 Oct
Sad... Bombay HC DB has already rejected his writ petition after he failed to co-operate with police, ran away from questioning from VP Road Police Station from fear of arrest & didnt submit his phone and laptop as well.
When there was a HC order he should have co-operated running away on pretext of washroom (as reported in media) & reprimanded by Bombay HC Division Bench isnt good for his cause. Plus he has Contempt & Defamation cases in Delhi by India Today & Times Group.
In Contempt Cases in Delhi High Court of India Today he will be tendering an Unconditional Apology per the last order for putting that Kalpanik Story out in violation of Court’s injunction.
Read 4 tweets
17 Oct
Our Kul Devi... Jai Ma Kali... 🙏🏼
#KalkajiMandir 🛕 #Delhi

माँ आदिशक्ति के काली रूप को समर्पित यह श्री कालकाजी मंदिर, जिसे जयंती पीठ या मनोकामना सिद्ध पीठ भी कहा जाता है। अतः यह पवित्र मंदिर माना जाता है, जहाँ सभी को अपनी इच्छाओं की पूर्ति हेतु माँ कालिका देवी का आशीर्वाद मिलता है।
#KalkajiMandir 🛕 #Delhi

कहा जाता है कि महाभारत काल मे, भगवान कृष्ण और पांडवों ने युधिष्ठिर के शासन काल में देवी कालिका की पूजा की थी। मान्यता यह भी है कि, कालकाजी मंदिर दुनिया का सबसे पुराना माँ काली का मंदिर है।
Read 9 tweets

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