1/A new @AnnalsofIM paper on #COVID19 in homeless persons finds that a “surge” of testing when cases are found may be a fine approach. Concern on this led some shelters to lock their doors to all new entrants until tests are negative. I'll review acpjournals.org/doi/10.7326/M2…
2/When #COVID19 hit, there were outbreaks in some cities. These triggered isolation & quarantine programs and hotel arrangements. In a Boston shelter, 147/408 persons, 36% tested +ve while 88% of these had NO symptoms ncbi.nlm.nih.gov/pmc/articles/P…
3/The fear of a #COVID19 shelter outbreak left many of us in other cities projecting a cataclysm, which didn’t happen across all communities. Our shelters locked down. We had many stressful discussions, and nothing happened. We wondered about our policies...
4/This study recruited folks in shelters, variably over time
Until 3/31: shelters recruited based on symptoms, with option for anyone to be tested 1x/mo(813 tested)
4/1-4/24: “surge testing” followed up known cases,at 6 shelters,no symptoms needed (315, or 621 tested, unclear)
5/29 infections were found among 1431 test encounters (2%). During routine testing before April 1, just 1% were positive.
During “surge” testing to follow-up after known cases more were: either 21/615 (3.4%) or 21/315 (6.7%). I’m awaiting a clarification from the author.
6/Regardless of the uncertainty , the key is that in a county with an early outbreak, routine testing in homeless shelters found very few cases. Follow-up of known positives found significantly more.
7/Among 29 persons who did test positive for SARS-CoV-2, 21 (72%) had NO symptoms. For the 8 who did, most had symptoms <48 hours. Many with symptoms had no infection
8/The 3 most-affected shelters relied on floor mats without dividers, & had a shortage of hygiene products, with older male residents.
Sounds like dividers are needed.
Only 1 of 29 positives came from a shelter with bunk beds (!)
9/The authors conclude that “passive sentinel surveillance” is likely going to delay recognition of outbreaks. However, a strategy of very active surveillance with a “surge” of testing to follow-up known cases looks pretty good
10/To me this report suggests some shelters can consider opening doors to newcomers without mandatory negative tests, depending on local conditions. But that is only possible if the local authorities also can commit to active surveillance & surge testing.
11/Obviously, it will be safer to offer hotel rooms or - over time- to continue efforts to end homelessness definitively both by housing individuals and by improving rental markets. @KellyMDoran@MKushel@DrEllenEaton@DrJeanneM
12/For a 100% independent take on the same study, let me commend that of @KellyMDoran - I drafted my tweets without having seen hers. We agree, but find different points of emphasis!
🧵1/Our @uabmedicine Grand Rounds will feature a diagnostic showdown between Dr Martin Rodriguez and ChatGPT4
I am scared here because I don’t want AI to win
2/the case features behavioral changes, swearing, cognitive decline, cough, progressive weakness over 3 years.
I wonder about infectious and rheumatic disorders. Maybe primary neurological
Aspirations after a cognitive change is possible
Dr Rodriguez opens. Not much to go on.
3/ChatGPT generated a lot of text read by Dr Kraemer but it is pretty good, with emphasis on neurological disorders followed by a disclaimer “please note that this does not substitute for professional medical advice”. Both want more information
Truth💣 1/ The “NARXCare” opioid Rx risk algorithm is in all Prescription Monitoring Databases,ie ~1 bn Rx’s/year
NOW in @JournalGIM
✅evidence does not yet exist to support it as safe or protective
✅It has flourished due to lack of federal oversight link.springer.com/article/10.100…
2/The authors, led by Dr Michele Buonara, review the core argument as one in which this algorithm with low evidence to its favor
and high risk of harm
has gone unregulated
despite apparently fulfilling @US_FDA criteria that mandate it be regulated
3/Nearly all prescribers and national pharmacies now see the Bamboo Health, Inc proprietary “NARXcare” algorithm in a more prominent position *than the prescription history itself” when they view a prescription history.
1/Arguing for methadone deregulation, Dr. Ruth Potee notes that in an auditorium of 400 addiction specialists, almost NONE prescribe methadone (because they can't)
"Methadone is a miracle drug that no one has access to"
There are more people who offer Botox than offer methadone
Patient: “I can still do my activities”.
Doc: "No way, not really. I read the SPACE trial, and there is NO benefit (that would outweigh the opioids’ risk)”
"Shared decision-making" seems *doomed* here
1/I watch with concern as DEA prosecutions of MDs still seem to rely on “they prescribed more than I would” despite a 9-0 ruling of
Supreme Court last year
Sudden termination of opioids & progressive abandonment of 5-8 million patients is dangerous
1/Even on inpatient rounds, it is possible to introduce the idea that addiction isn’t (only) in the brain.
I contrast @NIAAAnews “brain disease” against a behavioral economics vide substance use as a pattern of behavior occurring in relation to environmental context
2/On teaching rounds we read aloud and discussed the @NIAAAnews brain-science model of addiction, pulling just a few lines off their website
3/then we read lines from Chapter 39 of “Evaluating the Brain Disease Model of Addiction” - this presents harmful substance use as a pattern of behavior based on assessment of competing rewards, delay or uncertainty of desired rewards, risks and costs - ie behavioral economics