Short thread on the Chinese vaccine for COVID19. An irresponsible govt starts vaccinating it’s own people without adequate proof of either safety or efficacy, bypassing phase 3 trials. Then finds out it isn’t generating an adequate response. But the problems are much deeper.
The CanSino COVID vaccine uses the common cold vaccine as vector. But over half the people given the vaccine already had antibodies to common cold virus and hence it is virtually doomed to failure. A second dose won’t solve this.…
CanSino has decided to brazen it out by claiming that “we should not blindly follow experts” and that “It is unscientific to compare the antibody levels generated by different vaccine candidates, because varied testing methods could distort results”.…
They tried to cover it up by claiming it induced cellular immunity and not antibody response. However in their study published in Lancet, Chinese researchers had claimed 96% antibody response for the vaccine and said nothing about cellular immunity.…
The company declared its phase 2 trials in July. So far it has met with very little success for finding partners for international phase 3 trials. Only Russia and Pakistan have agreed. Russia is already mass vaccinating its own people without proper phase 3 trials.
Russia has started some trials on undeclared number of volunteers for CanSino vaccine a few days back. Interestingly it has also put its own much publicised vaccine on the back burner.
Link in next tweet.…
Bottom line is that neither Russia nor China can be trusted on their claims for the COVID vaccines.…
The other two Chinese vaccine companies Sinopharm and Sinovac are doing somewhat better than CanSino, and have managed a few international collaborators such as UAE and Philippines. But same pattern is seen here too: mass vaccination before trials.…

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More from @amitsurg

29 May
Let’s pause for a minute to see how big a violation of the law this is.
It seems donations (domestic or international) are being channelled to the lady’s personal account. Individuals cannot take donations, it’s completely illegal.…
If any funds have been collected as donations by an individual, it is illegal and punishable by jail term. If it is crowdfunding for a cause, the funds going to the individuals account will not count as donation. It will be accounted as their personal income in tax books.
If an unregistered body accepts foreign funds, it constitutes a grave violation of the FCRA Act and is again punishable by jail term. If an individual channels funds from overseas into their own account, it’s their income. Donor is cheated by labelling it donation.
Read 4 tweets
24 May
I’m bringing some good news today on the rural vaccine hesitancy front. But first, a short summary of our visit to a cluster of tribal villages at the base of Bhimashankar on Friday for planning our next series of rural health projects. #Thread
These tribal villages are the last cluster in Raigad district, before Pune District. About 15km from Kashele. On virtual meeting with locals, we got an impression that health related requirements were not significant. But site visit showed a completely different picture.
Most deliveries even today at this cluster are done at home. Emergency care is non existent because:
No ambulance services
Poorly equipped and staffed “district hospital” at Kashele which is hardly better than a PHC
Most patients get referred to either Karjat or Mumbai.
Read 9 tweets
9 May
Sharing some details about “oxygen rationing”. The municipal corporation collects data on oxygen beds and ICU beds, and allocates 5 lit/min/patient for oxygen bed and 20 lit/min/patient for ICU bed. The total estimated consumption in 24 hours is your hospital’s allocation. 1/n
This sounds reasonable and logical to an average person, doesn’t it. Equitable distribution based on needs. But to doctors this makes very little sense, because they know that the requirements of a COVID patient can change from 5Lit/min to 15Lit/min within hours. 2/n
The average consumption of an ICU COVID patient on BIPAP or NIV is 30-40 lit/min. On HFNC, it is 80-100 Lit/min. So how do authorities solve this? By declaring HFNC a waste of oxygen and banning its use. Despite the fact that HFNC reduces the need for ventilation by over 50%. 3/n
Read 6 tweets
1 May
The day before yesterday was supposed to be a day of celebration for us. Four patients with HRCT Scores 22/25 to 24/25 were being discharged after being on ventilator for over 3 weeks each. Including this patient.
Instead, it was ruined by a local hooligan politician. Thread.
This foul mouthed uncouth politician, Gurunath Gaikar, former corporator from Panvel Municipal Corporation, has a habit of threatening mob violence to get patients bills waived off. I have silently borne his shenanigans over the past few years, but this time he went even further.
While I was conducting an online consult, he tried to force his way into my cabin, banging the door, threatening to break it down, smash my hospital and assault me. Because a patient whose insurance had not been cleared due to incomplete documents didn’t want to pay the bill.
Read 5 tweets
24 Apr
We get between 5 and 20 doses per day for 50 patients, politicians and bureaucrats call even for those doses to be given to their relatives and friends. For every 5 who get remdesivir, there are 50 relatives and leaders demanding for their patient. Making it impossible for us.
There is no logic to the allotment. Absolutely arbitrary. 40 bed hospital gets nine doses, 50 bed 5 doses, 100 bed 10 doses and 20 bed also 5 doses. On top of it, if hospital asks relative to procure, officials instigate them by showing the circular of allotment of nominal doses.
As if it was not enough to be managing high volumes of seriously ill patients, we now have to spend additional precious hours explaining to angry relatives and politicians why their patient cannot be given one dose out of the pathetic allotment given by collector to our hospital.
Read 5 tweets
30 Mar
New President of the Indian Medical Association wants to use secular hospitals and medical colleges to convert medical students, doctors and patients to Christianity.
Quite self explanatory, isn’t it. Opposition to Ayurveda because people will learn Sanskrit and then everything will be Hindutva.
This is the immediately following paragraph. As per the President of the IMA, the fight against Ayurveda is actually fight against Hindutva and Sanskrit and fasting protest was inspired from Christian concept of suffering.
Read 5 tweets

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