Polish-American virologist Hilary Karpowski, who was the first man to create a live polio vaccine. He was born in an assimilated Jewish family in Warsaw, at that time in the Russian Empire. He finished medical studies at the University of Warsaw and also studied music at Warsaw
And in Rome. He luckily left Poland in 1939, and lived in the United States since 1944, where he worked as a professor at the Thomas Jefferson University. In 1952 Jonas Salk developed the first effective polio vaccine. It used a dead virus and was not fully effective. Several
researchers, including Karpowski and Alfred Sabin believed that an attenuated live vaccine would be more effective. Karpowski was the first to develop one, Alfred Sabin developed another (he initially made use of Karwowski’s work but Sabin’s vaccine is considered independent).
Because of Salk’s influence (and animosity) neither Sabin nor Karpowski could not perform large scale tests of their vaccines or get them approved. Sabin took his vaccine to the Soviet Union, where the leading Soviet virologist Mikhail Chumakov and his wife Marina Voroshilova
organised test on over 100 million people and mass production of Sabin’s oral polio vaccine (I am preparing a very long thread on the remarkable Chumakov family). Sabin’s vaccine eventually returned to the US and became the most widely used. Karpowski tok his vaccine to Poland
and to Congo. The vaccine (which like Sabin’s was orally administered) was a great success - in both countries polio was eliminated (so now I know that in my childhood I was vaccinated with Karwowski’s and not with Sabin’s live polio vaccine).
In 2007 Poland’s President Lech
Karpowski died in 2013 but not before becoming the “hero” of an awful conspiracy theory.
There seems to be something about viruses that attracts conspiracy theorists. If you search the internet for the great American virologist Robert Gallo, who proved that the HIV virus
causes AIDS (Gallo should have at least shared the Nobel prize that was awarded to Montagnier and Barré-Sinoussi, who were the first to isolate the virus but could not prove that it caused AIDS, it was Gallo who proved it) you can still find insane allegations that Gallo actually
created the HIV virus. But the same allegation was made against Karpowski by the journalist Tom Curtis, who alleged in “Rolling Sone” and in a letter to “Science” that Karpowski’s live polio vaccine caused the spread of HIV in Africa. The claim was that Karpowski had used in his
vaccine materials taken from chimpanzees, which were carriers of HIV. Karpowski published details of the production of his vaccine, from which it is clear that nothing to do with chimpanzees was used. Later research also debunked the hypothesis of a relationship between the polio
vaccine and AIDS in Africa.
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I have concluded that Chat GPT 5.0 (Thinking version!) is really excellent at solving elementary (that is Euclidean) geometry problems at the level of IMO’s (which is not surprising because it managed to get the equivalent of a gold medal at the last one).
I came to this conclusion because I tried the following “double test” this summer (I won’t have time for this once the term starts): I have been testing myself and Chat on geometry problems from various past international and national competitions. Of course my main interest was
wanting to find out if Chat was really as good at this as Open AI claimed, but also wanted to see if I could still do such problems myself (the last time I did such things seriously was over 50 years ago) and I have forgotten many theorems about triangles and circles etc.
People who write that “Israel is losing allies” obviously don’t know what the word ally means. Israel has not had an ally other than (arguably) the United States since 1956. Perhaps by “ally” they mean something like sympathizer, someone who will express regret when you die and
maybe make a memorial. Selling weapons, by the way, does not an ally make. Israel may no longer have sympathisers in Europe, but it sells more arms to Europe than ever before.
What is much more important than the loss of European sympathy is the fact that there are Saudi and UAE
accounts on X which are openly pro-Israel and they are not only tolerated but actually run by influential persons. Ten years ago that was completely unimaginable. Even the fact that negotiations are taking place between the Syrian government and Israel would have been incredible
Nixon is only partly right about Israel’s intelligence. In fact, Israel was well aware of Egyptian and Syrian mobilisation for war. The question was how to interpret it, because the Arabs were using a standard trick - repeated “exercises” that looked like preparation for invasion
To counter this, Israel would have to mobilise every time, which was very costly for its economy. So Dayan and ultimately Golda Meir had to decide what to do. However, Dayan believed that the Arabs were sufficiently deterred and would not initiate a real war but were only
trying to wear out Israel economically. The reason why he thought so was because Israel was believed to possess clear superiority in the air. This was not taking into account the new hand held ground to air missiles the Soviets had provided to the Egyptians. More importantly,
I am inclined to think that Trump really wanted to make a deal with Iran (for which, in his mind, he would have deserved a Nobel prize) but as Khamenei would not go along, he agreed to go along with Netanyahu’s plans. I think Bibi has so far played this masterfully- in anybody
in this affair is a chess player - it’s him. Winning over Trump was not easy as Trump is actually very risk averse but Netanyahu persuaded him that he would take all the risk of things going wrong and Trump would get the credit for success. I am inclined to believe that Trump’s
reluctance to support Israel’s action was real, but its effect was to lull Iran into a false sense of security. The evidence that Trump was hedging his bets is Rubio’s early statement, already after Israeli strikes began, that the U.S. had nothing to do with them and was not
Paradoxically, the stinginess and slowness of the U.S. military air to Ukraine under Biden, has had several good consequences. 1. It forced Ukraine, in spite of many obstacles due to corruption, bureaucracy and incompetence of its politicians, to start developing its own
weapons industry. On some areas, especially cheap drones it is now way ahead of what the U.S. can deliver (American drones have been one of the greatest disappointments). Moreover, in spite of all the obstacles put in their way by Ukrainian monopolies owned by powerful oligarchs,
most of the drones are now produced by small private enterprise, which is displaying far greater capacity for innovation than the Russians. 2. Because American aid was relatively small and unsophisticated, Europe is now capable of replacing most of it.
You can really tell a lot about people on X by using the Sherlock Holmes’s principle of “the odd that did not bark”. All you need to do is to observe what topics people are silent about.
When Biden was POTUS, it was not uncommon for conservative Never-Trumpers to keep silent on
topics that showed the Biden administration in a bad light. In some cases that included even the wave of antisemitism that swept over the Democratic Party after October 7.
Now, it’s the turn of Republicans and self-proclaimed conservatives to keep silent.
One of the favorite topics to keep silent about is the release of the Tate brothers and the role the Trump administration played in it. This is particularly noteworthy because they not only violently sexual predators but antisemite islamists.
(Here one should note the brave and