Laurence Badgley, M.D. Profile picture
Sep 29, 2020 11 tweets 2 min read Read on X
ARTHRITIS PREDICTS WEATHER? In previous posts (in my threadreader library) I have explained this phenomenon. The cause and effect is related to barometric pressure.
The body is like a sausage, with contained hard & soft tissues. Bones are connected by ligaments, which are highly imbued with pain fibers intended to keep us from injuring & stretching joint ligaments; to protect against being pulled asunder. Remember “Rack” of Inquisition fame.
When ligaments are lax from chronic wear, serial acute injuries, or from one serious joint injury, these injuries predispose joints to excessive range of joint motion & painful stretch of ligaments that tether these loose joints. Those with flexible joints potentiated for injury.
Women with Hypermobility & Ehlers-Danlos Syndrome particularly predisposed to these types of ligament injuries; especially ligaments of pelvic girdle, which can be permanently injured by pregnancy/birthing episodes, slip and falls, & lifting injuries (nurses particularly at risk)
When at sea level & normal barometric pressure, persons with injured joints experience a level of barometric pressure that bears upon the body sausage, & thereby compacting it; causing joints to more greatly form close & to have lesser ligament stretch.
Lower barometric pressures of elevated regions allow the body sausage to expand. Women with loose and injured ligaments often complain of greater pain of their joints at elevations above 4,000 feet above sea level. As the body sausage expands so do major joint laxities increase.
Before a storm there is commonly a lower barometric pressure, & the body sausage similarly expands; allowing joints greater laxity & opportunity to stretch injured ligaments; as joints shift through greater ranges of motion as the sausage expands.
In men, with robust pelvises, ligament laxity more often result of significant joint biomechanical injury; falling from heights & heavy lifting injuries. Yet men have the same sausage arrangement of their body tissues & can be equally reactive to changes in barometric pressure.
So can humans feel changes in weather in their bones? Yes they can & reason is the relationship of physical mechanical forces to tissue integrity. Human tissues are reactive to the variety of Newtonian forces of physics.
After years of studying relationships of human tissues to mechanical forces described by physics, I have increasingly pondered the failing of my medical school professors to relate tissue pain to the ambient gravitational field.

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More from @BadgleyLaurence

Apr 16
LOOSE JOINTS, HYPERMOBITY? Gravity is at play in these women with tissue variations. When joint are unstable the obvious compensation is “gorilla” muscles to take over lax ligament efforts. A wise Physical Therapist is key. Lots of dedicated exercise also.
LOOSE JOINTS INHERITED (-15% women) is normal. These woman’s have easier births & indigo-smart children. These women are often quite attractive and smart.
ABORIGINAL SOCIETIES
CHERISHED HYPERMOBILE
WOMEN BECAUSE THEY WERE SMART & PROLIFIC BIRTHERS. INTELLIGENCE GENES LIKELY GROUP WITH HYPERMOBILITY GENES & GENES FOR BEAUTY. MEN WANTED FECUND ATTRACTIVE WOMEN SO THEY SELECTED THEM OUT.
Read 6 tweets
Apr 14
HYPOPERFUSION? Yes, maybe sympathetic nervous system dominance + decreased pituitary vasopressin causing excess free water elimination in urine ⏩️ decreased blood circulation of hyperosmolar blood.
COVID-CAUSED decreased blood volume of blood that is too thick might explain orthodtstic hypotension, POTS. Might also explain the wormy blood clots.
COVID-CAUSED diminished total blood volume might evoke sympathetic nervous system activation to prevent hypotension and prevent syncope. Diminished blood volume would be expected to deliver less oxygen to tissues ⏩️ fatigue & exercise intolerance.
Read 5 tweets
Apr 9
TO BE GAY ON NOT, THE QUESTION? In ancient days of the mid last century, the proper medical terminology was “homosexual”. Homo is a Greek prefix for “man” such as used in our species name, homosapiens, I think. Along the way a new adjective/noun, a euphemism, was created, “gay”.
“GAYNESS” might be adverb. I don’t know, grammar not my long suit. In any case, Anthropologist of last century seemed to be of consensus that a fixed ~15% of the population was homosexual as a transcultural genetic characteristic of homosapiens. Indeed, genes direct hormones.
TO BE GAY OR NOT: THE “GREAT H & E DEBATE” (heredity vs. environment) is a dynamic that has ever lent unending entertainment and fascination to the study of the human condition & especially to the world of medical studies.
Read 7 tweets
Apr 6
MCAS IN LONG COVID: is possibly etiologic via biomechanisms known about MCAS, HYPERMOBILITY (HS) & FIBROMYALGIA (FM). Persons with HS & FM commonly suffer MCAS. Reason has been theorized that mast cells reside proximate connective tissue.
MCAS, HS, & FM: hyperflexible connective tissue evokes mast cell degranulation. Reactive substances provoke proximate neural tissues. Some experimental data for this dynamic. It might be that those with long COVID & MCAS expression might have hypermobility (about 15% women).
Read 11 tweets
Mar 12
IC CAUSE DISCOVERED: for years clinicians have been mystified by etiology of IC. Genes, microbes, toxins, & biochemistry have failed to provide insights. IC oft occurs in women who have Hypermobility Syndrome and/or IBS. These circumstances suggest that IC is a dysautonomia.
IC A DYSAUTONOMIA? parasympathetic part of autonomic system stimulates smooth tissues of bladder & bowel to contract/evacuate those organs. Over activity of this neural network is unmeasurable, as yet, in current medical sciences. Absence of evidence is not evidence of absence.
IC CLINICAL DATA: hypermobile women are potentiated for developing pelvic girdle instability from loose sacroiliac joint (SIJ) ligaments & are prone to Mast Cell Activation Syndrome (MCAS). Dr. Afrin’s book explains MCAS. I published case studies of IC remission via SIJ fusion.
Read 9 tweets
Mar 12
IRRITABLE BOWEL SYNDROME: doctors will tell you the cause is “unknown”. This is not true. IBS is commonly found in women either Hypermobility Syndrome. Reason is that these women are prone to pelvic girdle injuries and ligament laxity of one of the sacroiliac joints.
IBS & HYPERMOBILITY SYNDROME: This association well known in medical circles. Some of these women have regular daily frequent loose stools. Some have intermittent episodes of several days of constipation. Another set of these women have alternating constipation and loose stools.
IBS EXPLAINED: reason cause is “unknown” is that anatomical, tissue, and biochemical explanations are unknown and wanting. However, the dysfunction of the bowel suggests the cause is dysfunction of the autonomic nervous system, the parasympathetic and sympathetic.
Read 14 tweets

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