Thread by @DoctorTro

THREAD 🚨

Let’s talk about the headlines about time restriction!

Firstly I want to commend @ethanjweiss and all for a well designed study.

I poured through the data and wanted to share my thoughts.

jamanetwork.com/journals/jamai…

Basically the TRE group had more weight loss and fat loss although it wasn’t statistically significant.

Interesting on DXA it appears that there was a statistically significant reduction in lean mass.

Where did this come from?

Do we think that eating 12-16 hours of the standard diet would lead to significantly more lean mass than 8 hours?

It doesn’t seem likely.

So where did it come from?

The answers may be in the supplemental.

EXERCISE:
The late TRF group had decreased activity, daily movement, METS, steps, high activity, training frequency and training volume

 The TRF group exercised less! Much less!

SLEEP:
They also had worsened sleep timing/efficiency & more awake time

This could be an issue with meal timing close to sleep. eTRF versus lateTRF

But overall it seems sleep was significantly affected.

Lastly the DEXA measurements seem inconsistent

Do we think that TRF increases HEAD size ?

Or preferentially decreases left arm lean mass but not right?

I’m hoping to get the BIA data to see if that corroborates findings.

BOTTOM LINE:

This trial has given me pause, much to think about... for now, the only practice we will put into place is focusing on sleep quality, exercise and emphasize protein.

Certainly this study was well done and got me thinking. Kudos to the scientists!

For now: eTRF