Sean Casten Profile picture
Sep 29, 2020 20 tweets 5 min read Read on X
There is a very dangerous conversation going on suggesting that the path to beating COVID is through herd immunity. This is massively dangerous, and will lead to the death of millions of Americans. Facts matter. Here are the ones you need (thread):
1/ First, if you're not already following @gregggonsalves you should. He is an epidemiologist, spend decades studying AIDS and knows this stuff. See his thread on herd immunity here:
2/ The idea that we can choose to kill people or grow our economy is also wrong. Sweden, famously has tried to pursue herd immunity and only managed to kill more Swedes and hurt their economy.
medpagetoday.com/infectiousdise…
3/ This frankly isn't surprising. If lots of your neighbors are getting sick and dying from a contagious disease, you will be inclined to stay indoors, avoid restaurants, theaters and retail shops. You cannot grow the economy in the midst of a raging public health crisis.
4/ But let us suppose for a moment that you are completely amoral and you view economic growth as paramount, no matter how many people die. How many people would have to get infected in order to achieve herd immunity in that dystopian future?
5/ To know that, you have to know whether the virus will involve and how durable your immunity is once infected (assuming you are one of the lucky ones who doesn't die.) As former CDC director Tom Frieden points out here, we don't know those answers. drtomfrieden.net/blog/a-dozen-o…
6/ However, we do have a few recent studies that should scare the pants off you. After a surge in cases in Brazil, scientists concluded that "...up to 70%..." of the population may need to be exposed to achieve herd immunity. reuters.com/article/us-hea…
7/ This value is confirmed by a similar outbreak in Qatar where scientists concluded that "some communities" "have reached or nearly reached" herd immunity at infection rates of 65 - 70%. medrxiv.org/content/10.110…
8/ So now let's do some math. As of this morning, according to Johns Hopkins there are just over 7 million confirmed COVID cases in the United States, or ~2.2% of the population. Over 200,000 Americans have died, or 2.9% of those infected. coronavirus.jhu.edu/map.html
9/ To be sure, there are more infections we don't know about. And the excess deaths above average suggest that our death rate from COVID is also substantially undercounted. But let's go with the data we have. cnbc.com/2020/07/01/off…
10/ If we are to get to the ~65% infection rate that seems to be required for herd immunity, we will need to infect 65% x 332M, or 216 million Americans. Put another way, that's 209 million Americans more than we have already.
11/ Today, almost 3% of Americans who get infected are dying. But remember back in March when we were talking about the need to flatten the curve and hospitals were getting overloaded? The death rate then was >6%.
12/ We've learned a lot about ventilator management and treatment, but there is simply no way that a 30x increase in COVID infection rates doesn't overload hospitals. To assume death rates will be <6% is naive at best, evil at worst.
13/ 6% x 209 million = 12.5 million dead Americans. That is the population of New York and Los Angeles combined. That is the price you have to be willing to bear if you embrace herd immunity as a disease management strategy. It. Is. Brutal.
14/ And here's the thing: we don't have to do that. We can simply follow the examples that New Zealand, South Korea and so many other countries of done that has gotten the virus under control, even without a vaccine.
15/ Namely: Test. Contact Trace. Wear a mask. Social distance. Provide quarantine housing for those who are infected. We don't need to do any science to know whether that works - those countries have already proven it works.
16/ They did that from the start and felt much less economic pain because it's way cheaper to control the spread of a virus before it spreads. We should have, and if Trump hadn't politicized science we would have too.
17/ Is it hard to do that now? Of course it is. We all want our kids back in school and our business re-open. But that pain pales beside killing 12 million Americans.
18/ ANYONE suggesting that we should put short-term personal inconvenience ahead of public health is implicitly advocating for massive American deaths. Please don't do this. And please don't elevate voices who treat your life with such disregard. /fin
Postscript just shared with me from a friend who saw this thread. As the UK thinks about this question they are asking "what can we learn from the US debacle?". We didn't have to be the poster child in how not to handle a pandemic.

bmj.com/content/370/bm…

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More from @SeanCasten

Jun 28
Because a number of folks keep asking, let’s talk about why the Democrats overwhelmingly voted to table Al Green’s motion to impeach Donald Trump. TL;DR: if you want Trump to be out of office ASAP, this was the right call, right now. Read on for the explanation…
1. Shortly after my wife and I got engaged we took a vacation to Wyoming. In the course of a horseback trip, our guide, upon learning of our upcoming nuptials, prior to offering me some advice said “I’ve been married 5 times, so I think I know a little something about women”.
2. In that vein, in my 6 years in Congress, I’ve seen 3 house impeachments (Trump 2x where I voted yes, Mayorkas 1x where I opposed). None were removed. So I think I know a little something about removing people from office…
Read 14 tweets
Jun 22
This is not about the merits of Iran’s nuclear program. No president has the authority to bomb another country that does not pose an imminent threat to the US without the approval of Congress. This is an unambiguous impeachable offense.
I’m not saying we have the votes to impeach. I’m saying that you DO NOT do this without Congressional approval and if Johnson doesn’t grow a spine and learn to be a real boy tomorrow we have a BFing problem that puts our very Republic at risk.
To be clear, I do not dispute that Iran is a nuclear threat. That’s why Obama negotiated the JCPOA. But whether that is better resolved through diplomatic or military measures is not a decision that the executive branch has unilaterally.
Read 7 tweets
Jun 16
This is the reason why our Constitution has an emoluments clause. And every day that the House GOP refuses to do any oversight of the Trump family's grift is another day that our Republic gets a little more fragile. Thread: ft.com/content/13a6ce…
1. I've been raising a stink about Sun and Trump ever since he fronted $30M to World Liberty Financial, Trump's shady AF defi platform. thedefiant.io/news/tokens/ju…
2. That "investment" triggered provisions in the initial World Liberty financing documents that allowed the Trump family to take cash out of the business. In exchange, Sun got a stake in tokens that cannot be sold and are controlled by the Trump family. Literally nothing.
Read 10 tweets
May 25
Liz Truss lasted 49 days as Prime Minister. For context, that's less than 20% of the time that Kevin McCarthy lasted as speaker. And yet she - like him - thinks she has some wisdom to offer from that experience. (TL;DR: she's learned nothing.) washingtonpost.com/opinions/2025/…
As I said on the floor earlier this week, mediocre businesses hate competition for the same reason mediocre politicians hate DEI. Because they can't win in a meritocracy. But economic growth depends on competition - in labor and energy markets. Image
Under Bessent's watch, investors have fled US equities and treasuries for other countries. Saying that he should pro-growth is fine. But you should praise him (or Brexit supporters) for it in the same way you praise me for my ability to win the NBA slam dunk contest. Image
Read 7 tweets
May 20
Watching the Senate cloture vote on the (highly misnamed) Genius Act and keep thinking back to a conversation I had with a Senior official in the Biden WH 4 years ago. I asked him what he thought about crypto and he said “how do you define money?” Thread:
1. It was a very Socratic process, but goes to the heart of the rot in the crypto space. The whole thesis is that it’s currency. But it isn’t, and never will be, for the same reason that gold, fine art and pork bellies aren’t money.
2. “A store of value” isn’t the definition of money. After all, you can go back thousands of years in human history and dig up coins minted in precious or semi-precious metals with the Caesar / Emporer’s face. Why bother making that money if the metal had value?
Read 11 tweets
May 17
This is scary and highlights something that's painfully obvious in DC: smart people either don't want to work in this administration or are being turned away. But effective government - esp when crisis strikes - depends on having smart people around. washingtonpost.com/business/2025/…
And that's huge own-goal. There is a deep pool of talent in DC that wants to work in the WH. Not the electeds (no disrespect intended) but the people they hire. Because while winning an election depends on a whole host of factors, hiring staff is an embarrassment of riches.
Some of the smartest people I've met in my life are the career hill staffers, and the just-below-cabinet level tier in the WH. Thousands of people want those jobs and the WH gets to pick the best.
Read 12 tweets

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