Sean Casten Profile picture
Sep 29, 2020 20 tweets 5 min read Read on X
There is a very dangerous conversation going on suggesting that the path to beating COVID is through herd immunity. This is massively dangerous, and will lead to the death of millions of Americans. Facts matter. Here are the ones you need (thread):
1/ First, if you're not already following @gregggonsalves you should. He is an epidemiologist, spend decades studying AIDS and knows this stuff. See his thread on herd immunity here:
2/ The idea that we can choose to kill people or grow our economy is also wrong. Sweden, famously has tried to pursue herd immunity and only managed to kill more Swedes and hurt their economy.
medpagetoday.com/infectiousdise…
3/ This frankly isn't surprising. If lots of your neighbors are getting sick and dying from a contagious disease, you will be inclined to stay indoors, avoid restaurants, theaters and retail shops. You cannot grow the economy in the midst of a raging public health crisis.
4/ But let us suppose for a moment that you are completely amoral and you view economic growth as paramount, no matter how many people die. How many people would have to get infected in order to achieve herd immunity in that dystopian future?
5/ To know that, you have to know whether the virus will involve and how durable your immunity is once infected (assuming you are one of the lucky ones who doesn't die.) As former CDC director Tom Frieden points out here, we don't know those answers. drtomfrieden.net/blog/a-dozen-o…
6/ However, we do have a few recent studies that should scare the pants off you. After a surge in cases in Brazil, scientists concluded that "...up to 70%..." of the population may need to be exposed to achieve herd immunity. reuters.com/article/us-hea…
7/ This value is confirmed by a similar outbreak in Qatar where scientists concluded that "some communities" "have reached or nearly reached" herd immunity at infection rates of 65 - 70%. medrxiv.org/content/10.110…
8/ So now let's do some math. As of this morning, according to Johns Hopkins there are just over 7 million confirmed COVID cases in the United States, or ~2.2% of the population. Over 200,000 Americans have died, or 2.9% of those infected. coronavirus.jhu.edu/map.html
9/ To be sure, there are more infections we don't know about. And the excess deaths above average suggest that our death rate from COVID is also substantially undercounted. But let's go with the data we have. cnbc.com/2020/07/01/off…
10/ If we are to get to the ~65% infection rate that seems to be required for herd immunity, we will need to infect 65% x 332M, or 216 million Americans. Put another way, that's 209 million Americans more than we have already.
11/ Today, almost 3% of Americans who get infected are dying. But remember back in March when we were talking about the need to flatten the curve and hospitals were getting overloaded? The death rate then was >6%.
12/ We've learned a lot about ventilator management and treatment, but there is simply no way that a 30x increase in COVID infection rates doesn't overload hospitals. To assume death rates will be <6% is naive at best, evil at worst.
13/ 6% x 209 million = 12.5 million dead Americans. That is the population of New York and Los Angeles combined. That is the price you have to be willing to bear if you embrace herd immunity as a disease management strategy. It. Is. Brutal.
14/ And here's the thing: we don't have to do that. We can simply follow the examples that New Zealand, South Korea and so many other countries of done that has gotten the virus under control, even without a vaccine.
15/ Namely: Test. Contact Trace. Wear a mask. Social distance. Provide quarantine housing for those who are infected. We don't need to do any science to know whether that works - those countries have already proven it works.
16/ They did that from the start and felt much less economic pain because it's way cheaper to control the spread of a virus before it spreads. We should have, and if Trump hadn't politicized science we would have too.
17/ Is it hard to do that now? Of course it is. We all want our kids back in school and our business re-open. But that pain pales beside killing 12 million Americans.
18/ ANYONE suggesting that we should put short-term personal inconvenience ahead of public health is implicitly advocating for massive American deaths. Please don't do this. And please don't elevate voices who treat your life with such disregard. /fin
Postscript just shared with me from a friend who saw this thread. As the UK thinks about this question they are asking "what can we learn from the US debacle?". We didn't have to be the poster child in how not to handle a pandemic.

bmj.com/content/370/bm…

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More from @SeanCasten

Jul 30
Scott Bessent is a smart guy. But he only got the job as Treasury Secretary because Trump knows how to identify people who will roll over for him. Which is to say, he knows better. So let’s fact check his oped in today’s WaPo, shall we? washingtonpost.com/opinions/2025/…
1. First, if you want to understand what the crypto legislation that passed the House will actually do to financial markets, here are the facts.
2. Let’s define terms. “Blockchain technology” is just accounting. It’s a digital tag, tied to a digital purchase that records the buyer and seller. It is interesting, if not especially sexy. To the extent people can’t use it it’s because it doesn’t meet robust audit standards. Image
Read 23 tweets
Jul 27
Just learned that Mike Johnson, before coming to Congress claimed to be the Dean of a law school named after a pedophile. Which may explain a few things. Notably… Image
Image
… he then voted to table a resolution I introduced to compel the release of the Matt Gaetz ethics report, which also included significant allegations of underage sexual abuse. clerk.house.gov/Votes/2024490
Anyway, just worth pointing out that his decision to send the House home early rather than force release of the Epstein files is far from the first time he’s put the interests of sex offenders ahead of their victims.
Read 4 tweets
Jul 23
This is anti-scientific, immoral and economically irresponsible. I say this without hyperbole - when the history of this era is written, Donald Trump will have been responsible for more deaths than Stalin, Mao and Hitler combined. nytimes.com/2025/07/22/cli…
Millions, if not billions will die if we don't address climate change; some will survive but if rivers keep moving, coasts keep eroding, fires keep burning we will be forced to become migratory. That is a choice.
And that's of course in addition to the millions the are condemning to death from USAID cuts, or curtailing vaccines, and so much more. It is a trail of avoidable, wanton death. npr.org/sections/goats…
Read 4 tweets
Jul 8
I’m not wild about the cynicism here, partly because it blames all of Congress for things the Republican majority is jamming through, but more because it assumes that our founders actually created a Representative democracy. Some morning musings: washingtonpost.com/opinions/2025/…
1. To the first point, there are a host of issues that are squarely in the Democratic platform that regularly pass the House when Dems are in power but are blocked by Rs. Women’s rights, sensible gun control, campaign finance reform. All are supported by strong majorities.
2. There is no equivalent in today’s Republican platform but - and humor me on this before you blow up the mentions - that’s not entirely the Republican’s fault.
Read 12 tweets
Jul 2
If you've tuned into CSPAN anytime in the last 2 hours and found yourself slapping the side of the TV, wondering why the screen isn't changing, here's what's happening... Image
1. Lots of us including yours truly got in really late last night to vote on a bill that would slash taxes for billionaires, kick 17 million people off their health insurance, force lots of kids, seniors and veterans to go hungry AND is really unpopular. It's an easy "no" vote.
2. BUT, Trump wants it. And he wants it before July 4th so that he can go out and tell the American people how much he hates veterans, seniors, children and other Americans who are not billionaires. And if Daddy wants something, Republicans will do it.
Read 14 tweets
Jun 28
Because a number of folks keep asking, let’s talk about why the Democrats overwhelmingly voted to table Al Green’s motion to impeach Donald Trump. TL;DR: if you want Trump to be out of office ASAP, this was the right call, right now. Read on for the explanation…
1. Shortly after my wife and I got engaged we took a vacation to Wyoming. In the course of a horseback trip, our guide, upon learning of our upcoming nuptials, prior to offering me some advice said “I’ve been married 5 times, so I think I know a little something about women”.
2. In that vein, in my 6 years in Congress, I’ve seen 3 house impeachments (Trump 2x where I voted yes, Mayorkas 1x where I opposed). None were removed. So I think I know a little something about removing people from office…
Read 14 tweets

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