So as a patient with obesity and hyperinsulinemia begins a low carb diet there may be a reduction in LDL as the HLD of metabolic syndrome and fructose restriction comes into play...
But what happens as patients get leaner? Well there isn’t much data on long term low carb trials and certainly there isn’t much good data on the dyslipidemia of a population without metabolic syndrome
88% in the USA have one component of it... so what happens when you are free
The lipid models for people who are not eating are VASTLY different than those who are eating.
I would be remiss if I didn’t discuss the amazing work of @DaveKeto in articulating and demonstrating the energy model that explain the low carb abs intermittent fasting lipid panel...
Basically when metabolic syndrome is resolved and triglycerides are low, if someone has lost or losing weight on low carb, I would EXPECT an increase in TOTAL, LDL and HDL cholesterol especially if TRF is also being practiced.
Unfortunately, many don’t know how to interpret these numbers. As evidenced by a recent thread by @MichaelMindrum@KCKlatt where general recommendations of lowering fat, swapping for PUFA/MUFA & increasing fiber were recommended.
While these interventions won’t likely worsen a lipid panel, and is a reasonable start, it will likely NOT effect the cholesterol numbers as they expect in these specific patients, particularly if over 250 LDL like was the case brought up by them.
I don’t blame them for thinking it would, if had mild early success with such interventions but it doesn’t last.
THE MOST RELIABLE way, from my clinical experience, to decrease LDL in such a case, is ADDING starch, increasing meal frequency &/or gaining fat mass.
And since many are doing keto+IF for weight loss or maintenance, the reasonable option for many is to periodize starch to exercise and a modest amount in a second meal (separated from fat intake)
In the near future we will publish a small case series demonstrating this. But if you have followed @DaveKeto you could have expected the results. Massive decreases in LDL, amounts that are almost unfathomable.
To conclude this thread, I’d like to take this time and ask everyone to please donate to @DaveKeto charity. He will be putting your dollars to study these phenomena.
🔔 10 woke takes from the world of Modern Medicine in 2024 🔔
1) climate change is more important than human nutrition 2) obesity is genetic disease that requires drugs 3) obesity is healthy & should be embraced 4) diets don’t work, carbs are good, meat is bad 5) masking kids prevents death & causes no harm 6) any living thing needs 9-10 COVID shots, especially pregnant women & young children 7) COVID shots prevent long COVID & myocarditis 8) DNA & chromosomes don’t mean much, they are fluid, so is biology 9) the AMA covering the ethics of banning meat & NEJM covering climate change is more important than the diabesity epidemic 9) take drugs for every chronic disease 10) luck charms is healthier than eggs
People wanted context - lie 1
1) “Meat is unhealthy”
Meanwhile it’s associated with improved mental health, improved bone and muscle health and newer studies like that from PURE show that excluding it is bad for mortality
Lie 2
“Obesity is racist and it’s actually healthy”
Doctors, in an effort to be “inclusive” are ignoring the health impacts of excess adiposity
How statisticians and researchers arrived at the conclusion that the BlueZones are a FRAUD. 🤔
🔑 Thread with key excerpts
1/n
“When these states transition to state-wide birth registration, the number of supercentenarians falls by 80% per year“
2/n
“The US data support the hypothesis that improved vital registration should reduce the number of supercentenarians, and be associated with changing patterns of old-age survival, by reducing age-coding error rates.”
3/n
Having looked at 10,000+ CGMs let me tell you what you will learn...
1/9
Lesson 1: Hidden carbs are everywhere
- you will find hidden sugar & carbs everywhere.
You didnt know you could find carbs/sugar but you will:
hotdogs, sausage, beef jerky, spices, condiments, sauces, soups, broths, basically everywhere you didnt look.
2/9
Lesson 2: consider avoiding seed oils, vegetables oils, especially from restaurants.
Patients who switch to olive oil and avocado oil & hoke cooking seem to have improvement not otherwise explainable on CGMs
3/9
I love the curious & creative thinkers, the patients who question everything, b/c answering these questions makes me a better educator & confirms my commitment to lifelong learning & shared decision-making
1/10
I don't “kick patients out” for presenting difficult questions… a cruel, yet common, practice among paternalistic/authoritarian doctors... I instead embrace the questions
I use them as an opportunity to dig deeper, understand more and understand better.
2/10
I’ve had many of the same questions that my patients have had, why should I or why would I patronize a patient for thinking logically and asking questions?
In any case, these question have led me to the primary literature...