Dr Zoë Hyde Profile picture
Sep 29, 2020 7 tweets 3 min read Read on X
(1/7) Study of #COVID19 in US children. 277,285 cases were reported between 1 March and 19 September. Incidence higher in adolescents compared to young children (although more adolescents were tested). 1.2% were hospitalised (0.1% ICU), and 0.02% died.
cdc.gov/mmwr/volumes/6… Image
(2/7) The overall average weekly incidence was as follows:

Ages 5-11 years:
19 cases per 100,000 persons

Ages 12-17 years:
37 cases per 100,000 persons

However, more older children were tested than younger children. Image
(3/7) Overall, adolescents were more likely to test positive than younger children, but this was not the case in all regions.

In some regions, there was no difference in the proportion of younger and older children testing positive. ImageImageImageImage
(4/7) This suggests that other, unmeasured factors could explain the overall difference between the proportion of young children and adolescents testing positive.

It should not be assumed from these data that younger children are less susceptible to infection.
(5/7) The majority of children did not have any pre-existing medical issues (97%), although this was not the case for those who were hospitalised.
(6/7) At least 16% of those hospitalised had at least one medical condition (27% for those admitted to an ICU). Of those who died, 28% had at least one underlying medical condition.
(7/7) Among all children who tested positive and had at least one medical condition, the most common conditions were lung disease, including asthma (55%), disability (9%), immunosuppression (7%), and diabetes (6%).

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More from @DrZoeHyde

Sep 23, 2023
Policymakers shouldn’t be trying to manage COVID-19 as if it were seasonal influenza. It’s not and never will be. SARS-CoV-2’s greater transmissibility leads to faster viral evolution. This means waves of disease throughout the year, rather than a single winter COVID season. 🧵
Thanks to vaccination, COVID-19 is far less deadly than it used to be. But a virus doesn’t have to put people in hospital to be disruptive. Leaving aside the issue of long COVID, frequent waves of infection will grind down economic productivity.
Many seem to believe COVID-19 will become seasonal, but why should it? Influenza generally isn’t very transmissible and infects a small number of people each year. There’s plenty of time to design vaccines based on what’s happening in the opposite hemisphere of the globe.
Read 6 tweets
Jul 23, 2023
(1/6) Respiratory viruses are much more likely to spread indoors than outdoors, but outdoor super-spreading events can still occur if the conditions are right.

A new study describes a SARS-CoV-2 outbreak affecting 131 people at a night market. 🧵 Picture of a night market.
(2/6) The outbreak happened when a family of 3 people infected with the omicron BA.5.2 variant visited a night market in Zhejiang Province, China, in July 2022. They spent 1 hour and 4 minutes at the market.
(3/6) On the evening of the outbreak, it was warm (27 degrees Centigrade), humid, and there was very little wind.

Most of the market stalls had big umbrellas and it was crowded. The market had a capacity of 5,000 people.
Read 6 tweets
Jul 22, 2023
Could future vaccines be administered via a patch? Researchers have developed skin patches containing tiny “microneedles” made of sugar and salt which dissolve on contact with skin, painlessly administering a vaccine in the process. 🧵
asm.org/Articles/2022/…
A key advantage of this technology is that a vaccine patch can induce a special kind of immunity in the skin, known as mucosal immunity, which can prevent infection and transmission. Injectable vaccines may only prevent severe disease.
Skin patch vaccines are also likely to have fewer side effects because of the way they slowly dissolve over minutes to hours.

This slow-release formula is less likely to trigger flu-like symptoms that sometimes follow injectable vaccines.
Read 4 tweets
Jul 10, 2023
Imagine if you could rapidly detect COVID-19 in public places by testing the air. Now you can! Researchers have developed a groundbreaking new air monitor that can detect the presence of an infected person in as little as 5 minutes. 🧵
nature.com/articles/s4146…
The compact device, which measures 12 x 10 x 10 inches, has a sensitivity of ~80% and can detect as few as 7 viral RNA copies per cubic metre of air with a resolution of 5 minutes.
The major limitation of the prototype is noise (75-80 dB; similar to heavy traffic), although the researchers are trying to develop a quieter version with low-noise motors and/or sound-proofing.
Read 5 tweets
Jan 1, 2023
And now for something completely different.

Someone I know is a musician & recently released their first album. I think it’s pretty cool, and if you like rock, maybe you will too. 🤘🎸

You can stream the album here: ditto.fm/blonde-zombie-…

Read on to see reviews. 🧵
#NewMusic
Australia’s The Hard Rock Show called it “a really good, solid album - well worth your time.”
Germany’s Hellfire-Magazin rated the album 7.5 out of 10.

🇩🇪 hellfire-magazin.de/cross-eyed-lov…

🇬🇧 🇺🇸 …w-hellfire--magazin-de.translate.goog/cross-eyed-lov…
Read 5 tweets
Jan 1, 2023
A representative survey of US adults in mid-2022 found that 7% had long COVID (4-week definition; using questions developed by the UK’s Office for National Statistics).

One-quarter of these people said their daily activities were impacted “a lot”. 🧵
🔗 academic.oup.com/cid/advance-ar…
Around the same time in the UK, 2.8% of people aged 2 years and older were estimated to be living with long COVID.

🔗 ons.gov.uk/peoplepopulati…
But children are less likely to experience long COVID than adults, and the authors of the US study only surveyed adults.
Read 5 tweets

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