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Nick Profile picture
@nickcammarata
Oct 2, 2020 • 4 tweets • 1 min read • Read on X
Maybe contrarian opinion but we would learn 100x more about neuro if we put every dollar going towards connectomics towards psychedelics (also, learn way way more about mental health). Dynamics & interventions >> topology
Or maybe it’s the kind of contrarian opinion most good researchers agrees with but doesn’t feel safe bringing up at lab meetings. I care more about reducing the occurrences of these than I do about connectomics or psychedelics, as it controls the derivative of science
I don’t know a single neuroscientist that who thinks connectomics is a good dollar to insight investment, yet I don’t know of any who have written about this publicly. I don’t know what they’re say at intra-lab meetings but I suspect they keep quiet there too
I should add that I do think mapping low level neural mechanics is incredibly important, I just think connectomics is cargo cult mechanics

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More from @nickcammarata

Nick Profile picture
Jan 15
things don’t have to be going well to feel good. you can train to feel good unconditionally by stopping the clinging that underlies suffering and then try to improve your life and others’ once that’s sorted. feeling good can be a constant not a barometer of your life story
it’s a myth that the highs only feel good because of the lows. valence is absolute and having an amazing day every day is both possible and better than having an amazing day only sometimes
suffering more or less comes from a specific mental move you can learn not to do. there’s edge cases but that covers 99% of it. wellbeing has nothing to do with your life story, it’s a measure of how much you’re doing that move. and you can train to stop it nearly entirely
Read 8 tweets
Nick Profile picture
Jan 1
idk if i believe the log claim fully, but time def speeds up for most humans and meditation can undo it. hard to measure subjectively, but maybe by 2/3rds? almost everyone who meditates a lot for a decade says this, subjectively it feels like childhood again in a way
if you think your lifespan will be decided by a communal external event (pandemic, ai god, etc) rather than an individual health thing, slowing down subjective time might be the only longevity intervention one can do
you can feel this acutely after a sit. sit and do basically any type of meditation (breath, do nothing etc) for 45m, then feel time after when you get up. it'll be slower. that slower time becomes the new normal after a long time
Read 6 tweets
Nick Profile picture
Nov 22, 2025
everyone loves the do what feels good advice until they realize it leads to letting go and dissolving into nirvana
the both convenient and inconvenient truth about the physics of consciousness is that the right type of nothing feels better than almost every and possibly literally every something
though I guess it’s completely unsurprising from a mathematical sense if it turns out the limit of valence is zero. the answer to every question like this turns out to be zero, one, or infinity. the global peak was gonna be nothing or maxing it out. turns out it’s the former
Read 5 tweets
Nick Profile picture
Oct 17, 2025
my experience on "the path" or whatever so far is there's an incredible, shocking amount of karma stored in the body from unfelt emotions over what has been a kind of pretty overall great life. its wild how much the body stored. going through the storehouse is exponential with time, and can be done with almost no suffering, but lots and lots of feeling

at least thousands of hours total just letting contractions untense, on the hour long zoomed in view it feels like maybe this is all procedurally generated and fake but over the year to year view it's super obvious in a daily felt experience way that the total storehouse is decreasing, which is also what all the books since forever say is how it works
mostly i dont control when the things want to come up, i try to just drop whatever i'm doing and lay down for an hour and let them flow/uncontract unless i'm quite in the middle of something. more flexibility in your schedule def makes this easier. sometimes 30s, up to 1-2hrs
i think to some extent until abiding centerless awake awareness it's hard to work through the storehouse because the rate of contraction creation isn't low enough, need to stop the creation before you really work through it ime. which is also what the books basically all say
Read 11 tweets
Nick Profile picture
Aug 20, 2025
meditation might have the worst pedagogy of any field. they solved the cause* and cure** to suffering but hid it behind weird poems and deities

* clenching and resistance
** train to not resist, see how you gradually feel way better, see the non-specialness of self-sensations
I guess I don’t even know what to cause the field, bc meditation is more (part of) the cure than the field itself. maybe the field is early phenomenology researchers?
I wouldn’t say they solved psychology but they solved the most important problem in psychology, which is why is life hard and bad sometimes and what is needed to make it not that hard and mostly wonderful
Read 6 tweets
Nick Profile picture
Aug 18, 2025
any view of intelligence that's fixed across time (like iq) is dumb, my ability to solve hard intellectual problems over a given span of time varies like 100x depending on how i'm feeling. i'm bottlenecked on "time in ideal state" not peak capability and i suspect most are too
i do think intelligence disparities are very real but i rarely think it's the bottleneck even within like theoretical research sciences (most of what i do), but certainly in most applied areas
if we needed to compress it to numbers i think we should have two: intelligence variance and peak intelligence. basically every scientist i know has enough peak, the most productive ones i know stand out largely bc emotional regulation and good health to near it 90% of the time
Read 7 tweets

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