Covid Epi Weekly: The First Cluster

Cluster at White House is symptom and symbol of the failure of Federal response. Overconfidence in testing. Lack of basic safety precautions in crowded indoor places. Delayed isolation. Incomplete contact tracing. Failure to quarantine. 1/13
Testing only useful as part of a comprehensive strategy; it doesn’t replace safety measures. There are false negatives, and even if accurately negative in morning someone can be highly infectious hours later. Also need 3W’s: wear a mask, watch your distance, wash your hands. 2/13
Masks are important. Worth reading science review by the wonderful @CyrusShahpar. I learned from it. In addition to protecting others & yourself, masks may reduce inoculum and make it more likely that if you do get infected you won’t get severely ill. 3/13 bit.ly/36UK4tb
Rapid (and complete) isolation reduces secondary cases. There’s strong evidence paid sick leave reduces risk that people work while infectious from flu, almost certainly the same with Covid. The only valid reason to leave isolation is for a medically necessary procedure. 4/13
Contact tracing needs to be done quickly and expertly to find all exposed, trace source, expand circle of those warned, quarantine, test, stop outbreak. Let’s rebrand (accurately): case investigator-> patient support specialist, contact tracer -> Covid prevention specialist. 5/13
Quarantine means not exposing others after you’ve been exposed. Testing negative is not a get-out-of-quarantine-free card: you can be infectious soon after a negative test. But we should be able to optimize conditions and duration of quarantine based on data. 6/13
Here’s the epi-curve of the White House outbreak, from what has been publicly reported so far. Strongly suggests a common exposure on Sept 26 or 27. An investigation should be able to determine the likely source and identify, warn those most at risk. 7/13 tabsoft.co/3iLeGiX
The White House cluster is not over. There are likely to be additional cases. Great graphic from Cleveland Clinic. A series of measures needed to reduce risk, prevent illness and death, and accelerate economic recovery. Anyone have a better term for “comprehensive approach”? 8/13
In the US, hospitalizations, deaths trending downward slowly, but cases steady or increasing in most of the country. Only Maine and Vermont are reassuring. Anticipate continued case increases and eventual death increases. There will be 230,000 reported deaths by Nov 3. 9/13
In NYC uncontrolled spread in religious communities, increasing risk elsewhere. The ONLY way to stop it is to engage community, support and collaborate on education from within, appeal to and support religious leaders to establish and manage acceptable isolation facilities. 10/13
Schools, run well, don’t appear to be major amplification points. At Resolve, we’ve been saying since March, we must keep in-person learning as available as possible. Requires reducing spread in community, adapting school environment and policies. 11/13 bit.ly/2SHPdME
Moynihan: You’re entitled to your own opinion but not your own facts. Farr: The death rate is a fact; anything beyond this is an inference. The cumulative US death rate has now passed the UK's, approaching Spain's, highest of high-income countries. Read the graph, and weep. 12/13
We cannot become hardened to the horror of continuing, preventable Covid deaths. A death in the U.S. every 2 minutes. A death globally every 10-15 seconds.

Every life is precious.

Who saves a life, saves a world.

/end

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More from @DrTomFrieden

5 Oct
We still don't know key elements about the Covid outbreak affecting the White House. This is what needs to happen to assess the outbreak's impact and stop continued spread. 6 steps in an epidemiologic investigation:
Step 1: Establish the case definition: person, place, and time. For example, someone who had contact with anyone in the White House after September 18 and has a positive test for Covid (confirmed) or symptoms consistent with Covid (suspected).
Step 2: Find all who meet the case definition through active surveillance.
Read 8 tweets
2 Oct
Epi Weekly. 40 million plus 1. And…NYC is on the brink of a precipice.

A minimal estimate is about 40 million infections in the United States with the virus that causes Covid. The infection of President Trump is the most prominent, and one of the most telling.

First of thread/
My thoughts are with the President, First Lady, family, and all others infected with and affected by Covid. The President’s infection is a reminder that Covid is an ongoing threat. No one is safe – not even heads of state – until everyone is safe. fxn.ws/3ioVuaG
2/16
Risk of severe illness and death increases with age. A 74-year-old has approximately 3% chance of death, higher in males and people who are obese, and much higher if hospitalization is required. 85-90% of those infected in their 70’s will have no, mild, or minor illness.
3/16
Read 16 tweets
25 Sep
Covid Epi Weekly: People are tired of fighting the virus, but the virus isn’t tired of infecting people

As parts of Europe and the US show, turn your back on Covid and it will come back to bite you. Cases trending up again in many states, likely to hit 50,000/day in October.
1/9
2/9 Trends in positivity are getting harder to track. Per Covid Tracking Project, only 9 states documented to follow best practice of reporting antigen & PCR tests separately. (States should also report unduplicated people positive/tested, crossreferencing the two types of test.)
3/9 What starts in the young doesn’t stay in the young. @MMWR reports young adult infections were followed a week or two later by infections in people over 60. We are all connected. The sooner we recognize that, the sooner we can move forward more safely. bit.ly/369yrOu
Read 9 tweets
22 Sep
Every one of the 200,000 Americans killed by Covid is a tragedy, and most of these deaths did not have to happen. The future is in our hands.
We can save lives and accelerate economic recovery by putting science and public health at the center of our response. As the global death toll passes one million, this also means collaborating to improve public health systems worldwide.
There is no fairy tale ending to this pandemic—not even a vaccine.
Read 5 tweets
19 Sep
Epi Weekly Review: No Fairy-Tale Ending to The Covid Pandemic

Less testing, less information on tests, apparently less Covid. Positivity decreased 5.2 to 4.8% per CovidView. Testing decreased for multiple reasons, including antigen test results not being reliably tracked.
1/6
In the past week, most diagnosed cases in TX, CA, FL, IL, GA, MO, WI; these 6 states account for nearly half of diagnosed cases. But diagnosed cases only roughly a fifth of total infections. Virus spreading on campuses will spread to homes, parents, grandparents, and others.
2/6
3/6 @nytimes tracks counties with the highest rates. Here are top 28. They look pretty....red...to me. The virus doesn’t see red or blue states, only people it can infect. In too many places, the virus is still winning. If we work together but stay apart, we can stop the spread.
Read 6 tweets
14 Sep
1/ I received a note the other day from an 18-year-old high school senior who's concerned and feels he may be getting depressed about the future. He asked, Will this be forever? Are we doomed? THREAD:
2/ He asked when he'll be able to attend a sports game or concert again, when he'll be able to visit his grandparents, and if we'll ever get back to normal life.
3/ Young people are facing a lot of stress and uncertainty right now. Schools in many places are closing almost as soon as they reopen. Sports, concerts, and large gatherings are either cancelled or risky. Recent college grads are entering a flagging economy.
Read 16 tweets

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