Alina Chan Profile picture
20 Oct, 14 tweets, 6 min read
Very glad that the paper by @MonaRahalkar and @BahulikarRahul is finally published in a peer-reviewed journal. We need more scientists and journalists looking at possible links between SARS-CoV-2 origins and the 2012 Mojiang miners. frontiersin.org/articles/10.33…
I know of experts don't want to consider the miners because it is too far out of, frankly, anyone's field. But if experts don't look at the miners because it is outside their specialization, and journalists don't look at them because of the complex science, then who will?
Apparently, the answer is semi-anonymous users on twitter, who have recently named themselves DRASTIC (Decentralized Radical Autonomous Search Team Investigating COVID-19).

Their findings were described in the Sunday Times (still behind paywall) in July. thetimes.co.uk/article/seven-…
Journalists have been aware of the 2012 Mojiang miners since at least May of this year. The miners were even mentioned in the infamous NIH letter to EcoHealth (see point 5). But not followed up by journalists who covered the NIH-EcoHealth story. wsj.com/articles/nih-p…
The only journalist who followed up on this point was @ianbirrell for the Mail on Sunday: "The National Institutes of Health has asked if Covid-19 was linked to the deaths of three miners eight years ago" dailymail.co.uk/news/article-8…
The other articles that covered the story at the time failed to even mention the point about the miners. Maybe because it was so incomprehensible to a layperson? @WSJ @NatureNews @ScienceMagazine nature.com/articles/d4158… sciencemag.org/news/2020/08/n…
What is this all about? It's about SARS-like cases in 2012, Yunnan, China (3 miners died; 3 survived). These cases led to multiple top pathogen labs in the country repeatedly sampling bats and rodents in that particular mine for human pathogens for years after the incident.
Based on what is published, we know that no pathogen was ever found responsible for these SARS-like cases. But RaTG13, the closest virus (genome) to SARS2 was found in this mine in 2013. This was taken to the WIV in Wuhan and apparently full genome sequenced in 2018.
No further outbreak was detected in 2012. To quote an expert, "if three people died and it was controlled, would we know it? No. This is happening all the time, it's just in remote villages where people die. You bury them and end of the story, right?" nationalgeographic.com/science/2020/0…
2015, WIV collected serum from 218 people in Yunnan, finding 6 had IgG antibodies against SARS-like viruses (based on what they published, it looks like the assay works for both SARS1 and 2). They checked oral and fecal swabs from people for SARS viruses. ncbi.nlm.nih.gov/pmc/articles/P…
I don't want to keep repeating the same points, so please see these older threads:
Are you waiting for a person who has decades of infectious diseases research experience, an established career in investigative journalism, and the copious funding+international connections/intelligence to crack open this case?
I know people don't have time for this because it's an election year in the US and crazy shit is happening every week. But maybe after the election, when things calm down, someone should take a look at this.
I don't think such a person exists in the US or many countries' governments. We already know that an underwhelming number of people in politics are scientists (or individuals who value truth above all). Even CEOs of top biotech companies don't need to have science degrees.

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More from @Ayjchan

21 Oct
I need the scientists+editors who are directly or indirectly covering up severe research integrity issues surrounding some of the key SARS2-like viruses to stop and think for a bit.

If your actions obscure SARS2 origins, you're playing a hand in the deaths of millions of people.
I know it feels like your decision only impacts 1 publication or 1 genome. It's not.

Your decision helps bad actors to escape accountability and corrupt the public's knowledge on this issue.

Your decision makes this highly important research less transparent & less scientific.
If we don't fight to reduce pathogen spillovers into humans - whether natural or lab - it's a guarantee that more pathogens are coming from where SARS2 came from. People will find out some day and remember what top scientists and journals were doing to hinder investigations.
Read 20 tweets
18 Oct
The RaTG13 genome was just quietly updated on Oct 13, 2020.

Why is this happening!?
ncbi.nlm.nih.gov/nuccore/MN9965…
I thought the sample disintegrated in 2018 after full sample sequencing was done (even though the Nature paper said it was sequenced post-COVID). What is there to update?!
Do scientists need to be assigned to just sit and watch these data depositions for RaTG13, pangolin CoVs, RmYN02 to see what new data accessibility or updates occur over the years?
Read 8 tweets
14 Oct
"The Guangdong (pangolin CoV) strains, which were isolated or sequenced by different research groups from smuggled pangolins, have 99.8% sequence identity with each other."

I wonder how that could happen!

nature.com/articles/s4157…
Let me clear this up. The same senior authors have repeatedly published this -singular- batch of pangolin samples. Did they actually isolate the virus in culture? If so, why not share this with other researchers worldwide? See details here: biorxiv.org/content/10.110…
Read 25 tweets
13 Oct
COVID mink outbreaks: Netherlands (41+ farms), Denmark (63 farms), Spain, US (Utah, 9 farms; Wisconsin; Michigan)... we're going to have to add a host species feature to covidcg.org once sequences from mink SARS2 isolates are added to @GISAID. independent.co.uk/news/world/eur…
The only troubling part: "The (Danish) government says breeders with non-infected mink will be given 100 per cent compensation, while those with infected animals will receive less as an incentive for farmers to keep the infection out of their stock."
Wouldn't this incentivize farmers to hide mink outbreaks in their farms so that they can receive full compensation? Please reconsider this policy, Denmark!
Read 4 tweets
11 Oct
Read the 2nd Yan et al. report. It was frustrating... each statement requires fact-checking to the point where, instead of pointing out the errors, it may be better for someone to write an independent article discussing the circumstantial evidence pointing to lab origins.
The overarching message of Yan's 2nd report is that there has been unscientific behavior surrounding the reporting of SARS2-like CoVs. Based on this, they speculate that these genomes are coordinated fakes to make SARS2 look natural.
Again the report is littered with errors, but I do wonder why there hasn't been international impetus to investigate the source of these SARS2-like viruses. Why not go to the Yunnan mine to look for more RaTG13s? Why not investigate the miners - what actually happened in 2012?
Read 21 tweets
5 Oct
Beseeching employers in Canada to make work as remote as possible. If your employee is not, e.g., a healthcare worker, requiring in-person interaction, there is no reason why they should be out there at risk + increasing the risk for essential workers.
cbc.ca/news/canada/wo…
I wonder, often, at employers who think IT/admin people must be at the office. You can basically look South to see what happens when people treat this virus like it's not serious. Not everyone has access to (1) regular testing and (2) new therapeutics + a top class medical team.
The question at this point is how many deaths and disabilities your employer needs before they decide to make work remote. You already know cases are rising, that means many undetected cases. And you know people with pre-existing conditions have a fair chance of death/disability.
Read 8 tweets

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