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Vincent Rajkumar Profile picture
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27 Oct, 4 tweets, 5 min read
EQUATE: Our next @eaonc randomized trial for newly diagnosed myeloma is now open.
PI: @myelomaMD
#EAA181 #EQUATE
@SagarLonialMD @mtmdphd @NorthTxMSG @nsc_natalie @JanssenUS @NCICTEP_ClinRes Image
This investigator-initiated, @NIH @theNCI funded trial addresses the role of quadruplets in myeloma. It tests the hypothesis that adding a 4th drug will mainly benefit patients who are MRD+ after triplet induction, and may not be needed in those who are MRD-
Colleagues from @SWOG @ALLIANCE_org @BMTCTN helped design this trial and will work collaboratively.

@sgiraltbmtdoc @Myeloma_Doc
Pharma is doing many trials of 3 vs 4 drugs for all newly diagnosed patients. But our trial starts with a triplet and addresses who most benefits from addition of a 4th drug.

Accrual goal: 1450
Primary Endpoint: Overall survival

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More from @VincentRK

Vincent Rajkumar Profile picture
30 Oct
How COVID spreads indoors. Nice graphics and description from @elpaisinenglish

6 people are in a room for 4 hours. One has COVID but no one knows. @el_pais
@jeremyphoward @zeynep @trishgreenhalgh
1/

english.elpais.com/society/2020-1… Image
Even with safe distances, if no one is masked, after 4 hours talking in a closed room, almost everyone can get infected.

2/ Image
If everyone wears a mask but spends 4 hours talking indoors with no ventilation, many are still at risk of infection.
3/ Image
Read 4 tweets
Vincent Rajkumar Profile picture
25 Oct
Why does the US have the highest number of COVID cases and deaths in the world?

According to national leadership it’s the fault of:
China
Lockdown
Blue states
New York
The media
Fauci
Scientists
Doctors
Hospitals

My opinion:
Colossal failure of national leadership
1/
2/
Read 6 tweets
Vincent Rajkumar Profile picture
15 Oct
Slowly some CDC scientists and others are now coming out on the failures of the agency. It’s a little too late. We have lost >217,000 lives. Many of us called this out months ago. That’s when we needed scientists to speak up. @PSampathkumarMD @chadinabhan @CarolineYLChen
Here is @DrSidMukherjee offering to help the CDC make a website. 👇
Here is me lamenting about the failures of CDC in March.
Read 4 tweets
Vincent Rajkumar Profile picture
15 Oct
There is a group of people with excellent health insurance who hardly see a doctor or use healthcare resources: Doctors.

I don’t agree with the notion that people will abuse the healthcare system if they have good affordable healthcare coverage.
People go see a doctor if they have a health problem. They take medicines if they have a health problem. They get admitted to a hospital if they have a health problem.

There are better ways of having fun than going to a hospital.
There are always exceptions. For any system you create there will be a few people who abuse the system. But we can’t build systems around exceptions.

We need affordable universal healthcare. COVID shows us how your health affects others, and the health of others affects you.
Read 4 tweets
Vincent Rajkumar Profile picture
14 Oct
1.5 million US households have a net worth >10 million. They could pay for their own healthcare.

For the remaining 100 million, healthcare is so expensive one serious illness can wipe out your entire fortune. Not something you can save enough for. We need universal healthcare.
For example, for the disease I treat, multiple myeloma the annual cost of medicines alone is $200,000 to 300,000 or more. This can go on for >10 years. Each new treatment costs $20,000 to $30,000 a month.

Add to it cost of doctors fees, hospitalizations, lab tests, and imaging.
We depend on being able to be insured, having affordable premiums, and having adequate coverage.

Any one piece that’s affected will be a huge problem.

All 3 are threatened.
Read 5 tweets
Vincent Rajkumar Profile picture
14 Oct
Dusting of an old tweet. Trying to get to herd immunity as a planned strategy is sheer madness and will lead to a huge loss of life. @DrEricDing
1/ Wear a mask and try not to get COVID. By doing so:

You have a chance at avoiding COVID till we have a vaccine.

You delay COVID, & over time we will have better treatments that reduce chance of dying.

You will reduce viral dose if you do get exposed, and make COVID milder
2/ Young people have a much lower chance of dying of COVID. But it’s not zero. Some can become critically ill. You also run the risk of transmitting to older more vulnerable people.

I’m not arguing for lockdowns. Just try to social distance as much as possible. Wear a mask.
Read 5 tweets

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