After a sneak peek at their results last week, Pfizer and BioNTech are now finished testing of their vaccine. Results say it's 95 per cent effective with no serious safety concerns. A few other notable things 👇thestar.com/news/canada/20…
The size of the trial: People have asked about the speed which which these vaccines are being made. It is fast! But mostly because there's tons of money/support, not because testing isn't happening. Pfizer so far has trialed 43,661 volunteers at 151 sites in 6 countries.
Seniors: your immune system ages as you do, and seniors often need specially made vaccines. Experts have worried these first doses might not work for those who need them most. But Pfizer says their data shows 94% efficacy in those over 65. thestar.com/news/canada/20…
The cold chain problem: the new technology both Pfizer and Moderna are using has raised questions about refrigeration. Pfizer's has to be stored at -70 but they said today they've created special shipping containers that use dry ice to keep the vaccine stable.
What's next: Okay, Canadian pals, you're going to start hearing about emergency use authorizations. That is, so far, an American thing. Here, Health Canada will decide if it will be approved. That process has already begun, so stay tuned. thestar.com/news/canada/20…
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So that promising Moderna COVID-19 vaccine news from yesterday? There's actually a cool Canadian connection. Toronto-born stem cell biologist Derrick Rossi co-founded the company, and their work is based on his research. It involved... a glowing mouse. thestar.com/news/canada/20…
What's cool about what Moderna and Pfizer/BioNTech are doing is they're pioneering a new way of making vaccines. (And drugs in general!) They use mRNA, which takes instructions from DNA to make protein. Basically they're tricking your cells into making the proteins they want.
Back in 2010, Rossi had figured out how to do this in a petri dish. But he hadn't done it in a living thing yet. So he took the mRNA that had the instructions for making the protein that fireflies make. He injected it into a mouse. What happened? It glowed!