Any info out on the 'new strain' in phylogenetic / AA mutation terms?
Wonder if there's any chance increased circulation could be driven by false-negatives in testing. (happens in malaria with hrp2 deletion) 
So if I understand correctly it's this clade on microreact beta.microreact.org/project/4ebHf8…
N501Y also appeared during adaptation to mice science.sciencemag.org/content/369/65…
Filtering to only show samples after 15 Nov: Lime green strain making up majority of Kent cases and substantial proportion in London (and rare outside SE)
Microreact data over recent months, with rise of N501Y in Kent
re: this, Chris Whitty said at press conf that false negatives wouldn't be an issue
(clearer pies - but the relevant pie is Kent rather than the accidentally circled one)
A sense of the spread of this mutation. (This is a rough map of the UK: points represent genomes, with locations jittered and approximate) gist.github.com/theosanderson/…
More data should go up on microreact tomorrow. The last mostly-complete week at present is 8 Nov - 14 Nov. Here's how London and Kent look there (lime green substantially up on prev. week). Let's see how 15 Nov - 21 Nov looks tomorrow. If these slices expand again that seems bad.
(microreact didn't get pushed out today - I guessed it was on Wed because 9 Dec is in the current location name, but maybe it varies/appears a day later than the build)
Still no microreact but if you filter to samples in the metadata with "LOND" in the name you get
This is what that looks like if you expand the y axis to 100%
These annotations are about where the sequencing happened rather than where the sample was from, but there is correlation in broad geographical terms. LOND- London, CAMC = Cambridge Lighthouse, NORW - Norwich., MLK - Milton Keynes lighthouse. PHEC - PHE
• • •
Missing some Tweet in this thread? You can try to
force a refresh
