THREAD 1/5: I know this is not very nice just a couple of days before Christmas but I have to say I'm concerned about the CDC press release today, and the status our virus genomics surveillance program SPHERE
THREAD 2/5: Here's the statement: "Given the small fraction of US infections that have been sequenced, the variant could already be in the United States without having been detected"
THREAD 3/5: And this one: "The VOC 202012/01 variant has not been identified through sequencing efforts in the United States, although viruses have only been sequenced from about 51,000 of the 17 million US cases"
THREAD 4/5: By comparison the UK program for a much smaller country says it has sequenced 157,000 genomes, roughly that means we're performing at about 1/10th the capacity of the UK program?
THREAD 5/5: So not only are we missing the UK variant, but there may be other US homegrown variants that we're totally missing? How can this be, 10 months into the pandemic, still such terrible inefficiencies?
THREAD 6/5: Here are the links highlighted above from US and UK
1/n I’m seeing on social media and popular podcasts, awful nonsense and false claims about Covid immunizations in pregnancy causing autism in newborns. This is dangerous health disinformation at multiple levels. Here is the real story.
2/n First the adverse health impact of Covid on both pregnant mother and new baby is undisputed, it’s devastating for both, especially high maternal morbidity and mortality journals.plos.org/plosone/articl…
3/n moreover the health benefits of Covid vaccinations for both mother and newborn are also indisputable and life saving. This from @LancetDigitalH thelancet.com/journals/landi…
1/n Latest from @IHME_UW and their new Global Burden of Disease 2021 data for COVID19 excess mortality in 2021. A few things: First, it helps dispel the myth that LMIC nations on the African Continent were spared the ravages of Covid. A reason…
2/n a reason is low vaccination rates. My view: the overemphasis on speed or new technologies and innovations, there were insufficient mRNA and particle vaccine doses made in 2020-21, and these were bought up quickly by high income countries.
3/n I believe if our @TexasChildrens vaccine group received more international assistance we could have moved faster to help LMICs in Africa. As it is even without that help (or very modest help), at least 100 million doses of our low-cost, patent-free Covid vaccine administered
1/n Nuremberg 2.0 is a QAnon far-right fantasy that the Covid vaccine scientists & virologists will be tried at some sort of military tribunal similar to those following WWII. It’s an excuse to invoke Nazi imagery, designed to intimidate scientists, portray us as public enemies
@JHUPress 3/n the use of Nazi imagery to intimidate scientists has a historical basis, which I wrote about in a paper last year @ProjectMUSE muse.jhu.edu/article/902035…
1/n Our @TexasChildrens laboratory is rapidly accelerating a new human hookworm anemia vaccine for LMICs.
Fyi hookworm, malaria, yellow fever, dengue once common in East Texas (and in some cases returning). Here’s a hookworm map from early 1900s. Even Harris County,
1/n There have been several papers out in the last few months examining or reviewing the PEDIATRIC disease burden of Covid + the benefits of vaccination, will summarize some of the key interesting ones from 2023-24 here in this thread, in some cases also a popular article on it