Prof. Christina Pagel Profile picture
Dec 26, 2020 13 tweets 4 min read Read on X
THREAD: Where are we with Covid-19 in England now that the new tiers have started?

TLDR: nowhere good and things are quite scary. 1/13
Firstly, overall cases are rising sharply. Over 40,000 people tested on 21st Dec, tested positive - just in *England*. (this is "specimen date", not "reporting date"). 2/13 Image
Looking at it regionally, the SE is still the epicentre of new cases. London cases per 100K people now *much* higher than anywhere in the North in Oct/Nov.

BUT everywhere is going up. This is *not* just a Southern problem. 3/13 Image
Hospital admissions reflect case patterns - except that the NE & Yorks never dropped very low before plateauing. London, SE and East shooting up past the NW and Midlands. This is only to 21st Dec - probably much worse already :-( . 2nd plot shows how fast London is rising. 4/13 ImageImage
Overall hospital occupancy as of 24th December was only a few hundred people below the April peak. It's probably already above, or will be within a day or two. And, unlike April, we are not controlling the rise yet. 5/13 Image
Spare a thought for NHS frontline workers - already exhausted & traumatised - facing a rapidly worsening situation. We don't have unlimited docs, nurses or other frontline staff. They need our support. Why is this not in the media? 6/13
Will the new tiers be enough? In a word - no. Especially not after Christmas. The Tier 4 areas (inc the new tier 4) are shooting up still, but tiers 2 and 3 rising substantially too. This is not under control. 7/13 Image
Let's look at the new Tier 3 and 4 areas (mostly South and midlands) - and how they compare to the old Tier 3 areas (mostly North and midlands). Look how fast new Tier 3 places are going up. With old Tier 3 going up *and* new variant spreading - we need national tier 4. 8/13 Image
Christmas *will* have made everything worse - how can it not have? Test turnaround times have been getting much longer again, fewer people will get tests at Xmas, reporting will be slower... for the next week at least we cannot rely on the case data. Flying pretty blind. 9/13
Hospital data when it gets updated again (last updated on 24th) might help *but* reflects infections from 10 days or so earlier. But we desperately need an answer as to whether tier 4 is enough to bring R below 1. I don't know when we'll know. 10/13
And this is especially concerning as schools & unis due to start back in a few weeks. New paper from @LSHTM & @imperialcollege warned that Tier 4 with open schools & unis very unlikely to be enough. cmmid.github.io/topics/covid19… 11/13
We need a radical rethink of how we control the virus. The new variant is seriously bad news and, especially with Christmas, we are unlikely to have stopped it spreading across the country. Unfortunately I think the next 4-6 weeks are going to be pretty awful. 12/13
There really is no point in sugar coating it. If it weren't for the vaccine(s) I'd be seriously scared out of my wits. I still am pretty scared. The govt urgently needs a new plan - with national tier 4 being only the start. 13/13

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More from @chrischirp

Jul 3
THREAD: Given tomorrow's election, I've been thinking about our nation's (poor) health, the wider determinants of health and how these have worsened and what it means for policy....

TLDR: worrying only about NHS & social care is missing the point

let's dive in... 1/25
The UK has a health problem. After steady gains in life expectancy for decades, it flatlined during the austerity years and fell for the first time this century with the Covid pandemic.

The number of people out of work for long term sickness is near record levels. 2/25
There are huge inequalities between rich & poor. Boys born in the most deprived areas can expect to die almost 10 years earlier than their peers in the least deprived areas.

Even worse, they can expect to spend 18 fewer years of their life in good health (52 vs 70 years) 3/25 Image
Read 38 tweets
Jun 4
As ever, I am getting lots of pushback.
Here is a compilation of the European countries I've found with recent wastewater data. Some are going up a bit, some down a bit, some are flat, none are anywhere near previous peaks.
I can't see anything here to be panic anyone. 1/3
Image
I can't find the dashboard for Spain, but others saying it is in a wave. Perhaps it is. England has just had one - the last data we had (a couple of weeks ago from Bob Hawkins) looked as if our wave had peaked.
So, I'm not seeing reason to think things are terrible here! 2/3 Image
Yes there are new variants growing right now. They are not growing faster than JN.1 grew in December and that wave did not end up as bad as feared.
Clearly it remains true that Covid is NOT a seasonal disease (unlike Flu and RSV)
3/3
Read 5 tweets
May 8
Quick thread on the Astra Zeneca (AZ) covid vaccine since it's been in the news today.

TLDR there isn't a new "smoking gun", the AZ vax was one of first and cheapest, it saved millions of lives globally, there are better vax out there now, adapted to new variants 1/9
the AZ vaccine was one of the first approved at the end of 2020, cheaper than Pfizer, and - importantly - easier to administer in lower resource settings as it didn't require super low temperatures for storage 2/9
In most countries it was first rolled out in older adults. As it was rolled out in younger adults, a *very rare*, serious, side effect was noticed - it could cause deadly blood clots

This was spotted quickly and studied. Vax monitoring did its job. 3/9 Image
Read 11 tweets
Apr 2
A short thread on why this is not a scary chart and why all the evidence suggests that there is not much Covid around right now. 1/6 Image
the above chart is recorded covid hospital admissions / reported covid cases. It is close to 100% now *because basically only hospitals can report cases since Feb 2024*

It is to do with changes in case reporting and NOT hospital testing
2/6
In fact hospital testing has been steady since the change in testing a year ago (only symptomatic patients get tested now).

The % of people PCR tested who have Covid is 4% - there is no evidence that there are loads of symptomatic people in hospital being missed. 3/6
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Read 6 tweets
Dec 21, 2023
Beyond a shadow of a doubt that England is in its biggest Covid wave for well over a year now, with latest ONS infection survey results published.

I've written about it here
1/7 tinyurl.com/ru7h3m28
Image
The UKHSA have now published their modelled estimates of what percentage of English population has Covid. And as of a week ago it's high (4.3%) and rising.

Read all about it here!
2/7
It's highest in London, South East and East & in young and middle aged adults.
The main thing is it's going up and fast, so prevalence will already by significantly higher now than it was last week. 3/7
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Read 8 tweets
Nov 30, 2023
Short thread on what I said on Channel 4 news tonight.

1. Did I find Hancock a sympathetic witness?

A: I find it hard to have sympathy for someone who repeatedly claimed to have thrown protective ring around care homes, while discharging covid+ patients into them.

1/5
There were *28,000* excess deaths in care homes Apr-May 2020.

Harries thought it was "clinically reasonable" not to treat covid +ve residents in hospital. Even it was, it was NOT reasonable to return them somewhere they could infect so many other very vulnerable people. 2/5
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2. Did I think scientists bear blame for not emphasising asymptomatic transmission?

A: No, because they very clearly did advise there could be asymptomic transmission before March 2020 - sources in next tweet. 3/5
Read 5 tweets

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