Identical twins aren't 100% genetically identical. They differ by an average of 5.2 early developmental mutations. nature.com/articles/s4158…
Interesting paper! A few thoughts... [1/3]
Interesting paper! A few thoughts... [1/3]
1. It was always a safe bet that identical twins would be slightly different genetically. Indeed, there was already evidence for it (e.g., nature.com/articles/ejhg2…; HT @Scientific_Bird). The main contribution of the paper is carefully quantifying the differences. [2/3]
2. The fact that identical twins aren't genetically identical doesn't undermine twin studies. It may mean they slightly underestimate heritability. But the differences are so minor (M = 5.2 mutations in 3 billion base pairs) that, most of the time, it may have ~0 effect. [3/3]
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