India starts COVID vaccination. Watch how quickly they ramp up and overtake the US. @emilyschmall @Karan_Singhs nytimes.com/live/2021/01/1…
We have a public health infrastructure problem compounding missteps that will take a long time to reverse even after new competent leadership takes over. They are inheriting big problems. I hope I am wrong & that we do get a third of the population vaccinated in the next 3 months
India on the other hand despite huge disparity in wealth compared to the US, has good public health infrastructure. They also the foresight early on and manufactured lots of vaccine even before the trials were completed. @SerumInstIndia
I’m concerned about the report that only 11 million doses of Covishield have been purchased. But since lots more were manufactured Im hoping that this will be sorted out soon.

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More from @VincentRK

16 Jan
I’m looking forward to this month’s premiere of what I’m sure is one of the best movies: The White Tiger.

Congrats Mukul! @netflix #Oscars2021
Reviews are awesome! Can’t wait. @bimalarya
Read 4 tweets
8 Jan
CDC says asymptomatic transmission may be responsible for more than half the COVID cases. Kinda little late to come to this conclusion. Don’t you think?

We came to this conclusion almost from the outset of the pandemic.
cc: @ASlavitt
google.com/amp/s/www.wash…
There is simply no way for COVID to become the pandemic it did unless there was a lot of asymptomatic spread. Yet we had leaders from WHO on wanting “proof” before they would commit to anything. That’s like saying that cars without headlights are dangerous but we need proof first
In our anxiety to seem scientific, we forgot logic and common sense. I say it because I saw it happen over and over again.
Read 4 tweets
7 Jan
2020 was rough from an academic standpoint. We couldn’t get clinical or lab research done as planned. I did get some work done. Here are some I feel good about.

1. RCT in Newly diagnosed myeloma of VRd vs KRd. ENDURANCE @myelomaMD @eaonc @TheLancetOncol thelancet.com/journals/lanon…
2. RCT of Len vs Observation in Smoldering myeloma. @SagarLonialMD @eaonc @ASCO_pubs ascopubs.org/doi/full/10.12…
3. RCT of Ixa-Rd vs Rd in Newly diagnosed myeloma. TOURMALINE MM-2 @MayoMyeloma @ASH_hematology #ASH20 ash.confex.com/ash/2020/webpr…
Read 10 tweets
6 Jan
I agree. This is not good. We are only as strong as the weakest link. Politicians will not realize this.

I heard from a friend overseas last week. On New Year’s Day. That everyone in his country, rich or poor, citizen or immigrant, legal or illegal, will all get free vaccine
We are in dangerous times. Physicians need to speak up.
The reason we need to make sure everyone has the vaccine is for public health. If we don’t achieve high rates of vaccination there will be no herd immunity, the virus will continue to find susceptible hosts to attack and continue to mutate.
Read 4 tweets
4 Jan
2020: 20 million Americans got COVID.

How well could we have done?

If we had done as well as
Germany: 14 million fewer;
South Korea, Australia, New Zealand: >19.5 million fewer.

@ASlavitt had a thread on this 6 months ago. It’s still holds true.
We had 350,000 deaths due to COVID.

How well could we have done?
If we had done as well as Germany: 200,000 fewer deaths;
South Korea, Australia, New Zealand: >300,000 fewer deaths.
What went wrong? What could we have done better. The overriding problem was failure of leadership, lack of strategy, and mixed messaging.

We lost our standing as a country to look up for expertise in solving a public health problem. That’s going to be hard to get back.
Read 6 tweets
20 Dec 20
“Worrying is like rocking a chair. It give you something to do. It doesn’t get you anywhere”. Famous saying.

Worried about mutant COVID? Just follow what’s in our control: Masks, social distance, and get as many people in the world vaccinated as soon as possible.
Some of us discuss the mutant strains just to increase awareness and to keep people informed. The goal is also to make sure leaders are appropriately concerned and act. And to not make the same mistakes of months past. Not to make the public anxious.
My feeling remains the same. Once people are vaccinated even if the virus mutates the probability that it will have the ability to evade immunity from infection or vaccination adequate enough to cause severe illness and consequently this type of pandemic will be very rare.
Read 5 tweets

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