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Kevin McKernan Profile picture
@Kevin_McKernan
Feb 10, 2021 • 10 tweets • 4 min read • Read on X
Scrolly
Evidence of rigged Peer Review @Eurosurveillanc
@PlanetWaves
@Bobby_Network
@RetractionWatch
@goddeketal
Admits to being the reviewer of the Corman-Drosten Retraction request.

This is 60+ pages discussing Primer Dimers and other primer design problems.

But he just said he didn't look at the primers for this assay??

That is why Anon Peer Review is a Fraud.

@RetractionWatch
Bustin vs Andrew Wakefield.
Bustin testified under oath about the problems with Andrew Wakefields RT-qPCR. This is a big case.

It shares many of the same problems as Drosten?

OK for Drosten.

Not for Wakefield?

There is a difference.

Bustin was paid 220,000 pounds for it.
What is it called when you contradict yourself multiple times under oath?

What is it called when you do it for 220,000 Pounds?

What is it called when you flip flop like this and it shuts down the world?

Still think Anon Peer Review is a good idea?
Bustin vs Wakefield


Bustin Vs Borger


Planet Waves Podcast
@PlanetWavesmega.nz/file/ocZAXBzS#…
cormandrostenreview.com
So was Wakefield rightfully scrutinized and Drosten given a hall pass?

Many of the concerns raised about Wakefields qPCR are significant. But the one most cited (contamination) by Dr. Bustin was not.

He claimed Wakefield omitted an RT-Step.

Bustin is emulating this in 2020.
Wakefield is also nailed for Lack of an SOP.
Same story in the Drosten review.

The proper way to address DNA or RNA contamination is with DNases and RNases.
RT enzymes are active at RTemp and as the cycler ramps its temperature up to 95C.
#BustinBusted
nature.com/articles/s4159…
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Bustin continues to push for limited to No RT step in qPCR.
Precisely what he persecuted Wakefield for…and was paid handsomely for the testimony he has since contradicted.
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More from @Kevin_McKernan

Kevin McKernan Profile picture
Feb 16
Pay attention to IVM/FenBen for cancer.

IVM prevents SV40 promoters from entering the nucleus but blocking importin A/B
Yes, ivermectin is known to inhibit importin α/β-mediated nuclear transport, which is relevant in the context of SV40 promoters.

Mechanism:

•Importin α/β Pathway: This transport system is responsible for shuttling proteins with nuclear localization signals (NLS) into the nucleus. Many viruses, including SV40, hijack this pathway to deliver their regulatory proteins (e.g., Large T antigen) into the nucleus for replication and transcriptional activation.
•Ivermectin as an Inhibitor: Ivermectin binds to importin α/β and disrupts its function, thereby preventing nuclear entry of proteins that depend on this transport mechanism.

Implications for SV40 Promoters:

•SV40 Promoters: The SV40 early promoter is often used in molecular biology due to its strong transcriptional activity in mammalian cells. However, its transactivation requires the nuclear localization of SV40 Large T antigen, which depends on importin α/β.
•Blocking Nuclear Entry: If ivermectin blocks importin α/β, it could prevent SV40 Large T antigen from entering the nucleus, thereby reducing SV40-driven gene expression and viral replication.

Experimental Evidence:

•Studies have demonstrated ivermectin’s ability to inhibit nuclear import of viral proteins from various RNA and DNA viruses (e.g., HIV-1, Dengue, and even SARS-CoV-2).
•SV40 Large T antigen is known to require importin α/β for nuclear entry. If ivermectin blocks this pathway, it could theoretically interfere with any SV40-driven transcription or replication in systems using this promoter.

Would you like references or more experimental details on this?
Certainly, here are some key studies that provide evidence on this topic:

1.Ivermectin as an Importin α/β Inhibitor:
•A study by Wagstaff et al. (2012) demonstrated that ivermectin specifically inhibits importin α/β-mediated nuclear import. The researchers found that ivermectin effectively blocked the nuclear import of proteins dependent on the importin α/β pathway, without affecting other nuclear import pathways. This inhibition also correlated with a reduction in the replication of viruses such as HIV-1 and dengue virus, which rely on this pathway for nuclear entry of their proteins. (pmc.ncbi.nlm.nih.gov)
2.SV40 Large T Antigen and Importin α/β:
•The SV40 Large T antigen contains a nuclear localization signal (NLS) that is recognized by importin α, facilitating its transport into the nucleus via the importin β pathway. This nuclear import is essential for the Large T antigen’s role in viral replication and cell transformation. (en.wikipedia.org)

These studies collectively suggest that ivermectin’s inhibition of the importin α/β pathway could impede the nuclear import of SV40 Large T antigen, potentially affecting SV40 promoter activity and viral replication.
Read 14 tweets
Kevin McKernan Profile picture
Feb 4
I watched this last night as people had questions about the gene therapy described in it.
A thread on my take
Background.
Im against the drug war. People should be free to Biohack. Even if the government mandates water, I have a problem with it. Not the water but the force and threat to freedom.
I'm glad Bryan is on this journey and sharing what he finds.
I don't care if he sells stuff on the way. Voluntary economic interactions are legit. People who like to control the narrative will complain.

I couldnt do 100 supplements/day but maybe he'll figure out the key 4-5 that do 90% of the work for others.
Read 17 tweets
Kevin McKernan Profile picture
Jan 22
Profiling circulating DNA is a thing. I’m just skeptical of the tox seen with LNP delivery of mRNA.
We took the cover of Science Translational Medicine in 2010 with profiling circulating tumor DNA.

pubmed.ncbi.nlm.nih.gov/20371490/Image
I’ve used these profiles to characterize my father’s prostate cancer.
BRAF-K601E Mutation called for AKT1 inhibitors.
Some Cannabinoids are AKT1 inhibitors.
David Meiri does some of the best work on profiling cannabinoids for cancer

AKT1 and Cannabinoids

pmc.ncbi.nlm.nih.gov/articles/PMC47…
Read 9 tweets
Kevin McKernan Profile picture
Jan 14
Holy Sh$t
@P_J_Buckhaults just sent me this.

File under: DOES NOT STAY IN THE DELTOID!

nature.com/articles/s4158…Image
Image
@P_J_Buckhaults The reason this is a Holy Sh$t is that the resolution and sensitivity is a game changer.
They dont need to load up 100X the dose to track this. Image
@P_J_Buckhaults Would be nice if they looked at Ovaries/Testes Image
Read 5 tweets
Kevin McKernan Profile picture
Jan 10
Ivermectin and SV40. Image
pmc.ncbi.nlm.nih.gov/articles/PMC74…Image
Read 5 tweets
Kevin McKernan Profile picture
Jan 3
🔥My Review of the Recent FDA-Student DNA contamination Paper.🔥 Image
6-470X the limit but this higher limit is from UV spec which is likely inflating the signal Image
The Qubit data did not run DNaseI standards.
This leads to under reporting the DNA 70%.
Georgiou et al. Image
Read 6 tweets

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