Thread by @waittwoweeks

CAS SPECIAL PROJECT

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The CAS' strategic leading technology category B special "Pathogen Host Adaptation and Immune Intervention" (hereinafter referred to as the "special project") has been approved and will enter the implementation phase (2018-2022).

@BillyBostickson

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@Daoyu15 @gdemaneuf @BillyBostickson @WhereIsYanLing @uacjess

archive.is/VsPaD

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"Clarify the source and transmission mechanism of the pathogens of emerging and sudden infectious diseases such as flu and SARS, provide a theoretical basis for the early warning and forecast of emerging and sudden infectious diseases...

the special project has five projects

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Project 1: Research on virus traceability, cross-species transmission and pathogenic mechanism

person in charge:

Shi Yi
Shi Zhengli

2. Molecular mechanism of virus cross-species infection and pathogenicity:

3. The interaction mechanism between virus and host:

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Project 3: Immune recognition and activation of pathogens and immune memory

Project 3 person in charge:

Tian Zhigang
Tang Hong

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1. Immune recognition and regulation of pathogens:

2. Immune escape and exhaustion of pathogens:
Establish an internationally leading animal model of chronic viral infection

3. Immune damage and malignant transformation mechanism of pathogens:

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Project 4: Research on new strategies and new theories of immune intervention

Project 4 person in charge

Yan Xiyun
Yan Jinghua

1. The functional transformation...

2. Neutralizing antibody...

3. New strategies for the design of new vaccines and adjuvants

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@BillyBostickson @uacjess @WhereIsYanLing @gdemaneuf @Daoyu15

Project 5: New methods and technologies for infection and immune research

person in charge

Zhang Xianen
Cui Zongqiang (WIV)

2. Human-derived tissue and organ chips and humanized small animal models:

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It is required to ensure that more than 4/5 of the time is used for the research work of this pilot project. Those who apply for this special task shall not simultaneously undertake other research pilot projects task.

it is expected to achieve significant Original results

1. The traceability, evolution and transmission mechanism of new pathogens:

"For patients with unexplained disease, as well as diseased and healthy animals (including samples from my country's surrounding areas and the Belt and Road region)"

@BillyBostickson @Ayjchan

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