If you’ve ever spent $1000-$10,000 in one place (either your own money or your company’s money), how much time do you usually spend researching the decision?
If you’ve ever spent $10,000-$100,000 in one place (either your own money or your company’s money), how much time do you usually spend researching the decision?
If you’ve ever spent $100,000-$1,000,000 in one place (either your own money or your company’s money), how much time do you usually spend researching the decision?
If you’ve ever spent more than $1M in one place (either your own money or your company’s money), how much time do you usually spend researching the decision?
For all above polls, include all kinds of institutions (gov’t agencies, nonprofits, etc). I said “company” instead of “organization” or “employer” by mistake

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More from @s_r_constantin

24 Feb
Starting to research this, and OMG the quality of research is bad.

“Do CEOs who do X get better company outcomes?” papers are always tiny studies, with all measures *including company performance* self-reported.
I think I still believe one of these papers more than I’d believe a “take” in the news or on Twitter, but less than I’d believe the opinion of a 60-year-old who has a lot of management experience.
We’ll see if the data on investors or investment analysts is better.

I did find one bizarre paper that said the rank of an investment analysis firm was *negatively* correlated with how frequently they reported using the company’s library. (Back before the Internet.)
Read 5 tweets
22 Feb
@oscredwin makes the point that this poll conflates testing the two questions “do most people spend more time deliberating over larger amounts of money than smaller amounts?” and “do people who ever allocate >$1M spend less time deliberating over $100k than those who don’t?”
It’s arguably rational to spend more time deliberating over more money, all else equal, and it’s also arguably rational for your research-time per dollar to decline as your hourly wage increases or as the amount of money you have to allocate increases.
What I’d really like to know is if my subjective impression is correct that as people gain in wealth/authority/seniority, they have a higher “activation energy” to go check object-level facts themselves. More than you’d expect just from their time being valuable.
Read 13 tweets
11 Feb
With an endorsement from Derek Lowe, my opinion is superfluous, but yes, this study looks legit. Semaglutide causes weight loss in a large, rigorous controlled trial. 🧵follows.
1961 participants, randomized 2:1 to semaglutide or placebo, plus a 500-calorie deficit and exercise program. Mostly white and Asian, mean BMI 38.
Over 68 weeks, the treatment group lost a mean of 16% of their body weight, or 37 pounds. The control group only lost a mean of 3% or 7 pounds.
Read 12 tweets
5 Feb
I looked into this, because yay citizen science.

I could not find one research study using any of the peptides in the RADVAC white paper that found they inhibited SARS-CoV-2 infection in cells, let alone animals or humans.
All those peptides come from in silico studies: “the computer said they ought to bind to various viral proteins.” Plus a lot of theory/mechanism argument.
You have the legal, and IMO, the moral, right to experiment on yourself. But I don’t think this is very likely to work.
Read 8 tweets
10 Aug 20
The most irritating thing about smartphones, to me, is that it’s more difficult to switch from one webpage to another on mobile than in a desktop browser. It makes it hard to do something like “take notes including links from a variety of websites.”
The second most annoying thing is that I can’t log into sites on my phone if their passwords are the long forgettable strings of letters and numbers that my laptop password manager remembers for me.
The third most annoying thing is that i’m slightly slower at typing on a phone than a keyboard.
Read 5 tweets
31 Jul 20
The trend in deep learning for a lot of applications, for most of the past decade, seems to have been “you get out what you put in” — performance gains are proportional to increases in computing power.
I haven’t found anything I’m confident is a exception to that trend, in the direction of “performance grows faster than compute”. I’d be willing to bet that there aren’t any.
As long as that continues, it seems to me that the main question is how fast the cost of flops drops and how long it will continue to be profitable to keep buying more & better hardware.
Read 14 tweets

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