1/ Ozone has been regulated in the US for 43 years due to its adverse impacts on respiratory health. The image on the right shows a healthy lung tissue (top) and lung tissue exposed to ozone at only 20 ppb during four hours of moderate exercise. ..... 
2/ On the top image, the cilia on epithelial cells stand upright and orderly. This is important for clearing mucous that may convey deposited particles, including those that may contain pathogens. Bottom image ...
3/ In the bottom image the cilia look less ordered, less upright, and the epithelial cells appeal distorted. The arrows point to neutrophils, indicative of inflammation due to inhalation of ozone.
4/ The image to left is based on ion generators tested by @IAQinGWN in 2000s that emitted approximately 1 to 5 mg/hr of ozone. Newer bipolar units often emit less (by design), but may also be even LESS effective than their (fairly ineffective) predecessors at removing particles.
5/ We put this in the context of how much higher the 24-hour average outdoor ozone concentrations would have to be for a median-sized US home at different air exchange rates to yield the same indoor concentrations stemming from (older) ion generator emissions.
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