The J&J clotting side effect appears similar to the AstraZeneca one. The same basic issues arise:
1) Can be serious 2) Very rare 3) Seems to impact mostly women under 50 for some reason 4) Still no reported cases of it in Canada (for AstraZeneca)
It’s not just a typical clot. It’s a type of clot with low platelets.
Platelets are like the mini-goombas from Super Mario. That may be too niche of a reference. But when you get enough of them banding together on Mario, they slow Mario down so he can’t move.
So platelets usually help in CAUSING clots. That’s useful. They help make sure you don’t bleed out if you get a cut.
On the surface, it’s a bit weird you get clots with LOW platelets. Usually low platelets mean less clotting.
It’s not unheard of though. We see this with heparin
Heparin is used as a “blood thinner”. It usually prevents clots. But a rare side effect can cause your immune system to go a bit weird. You get low platelets and, sometimes, clots.
Notably, the risk of getting this from heparin appears higher than getting it from the vaccine.
Why are we getting this side effect with the J&J and AZ vaccine.
We don’t really know yet. I’ve seen a bunch of theories. Is it hormone related or an interaction with birth control? Is it not even related to the vaccine and these events would’ve happened anyways?
One of the reasons we don’t know the exact cause: these events are so flipping rare.
We all take things literally over the counter (like ibuprofen) that cause far more death every year, even taken appropriately.
From Ontario’s COVID-19 Science Advisory Table:
(This is related to the clotting issue with AstraZeneca specifically)
This is a common thought but in this case not accurate. These events are so rare, literally no amount or length of clinical trials would’ve been able to pick them up. This is something that can only show itself once you vaccinate millions.
I’m not in charge of pausing or going forward with vaccines. However, the juxtaposition of these two stories on my feed is quite striking as it relates to our current situation.
Our ICUs are full of younger and younger patients. Vaccine side effects are thankfully rare.
Update: One case in Canada
(Unclear on the details or age.)
I have been avoiding writing a thread about this even though it’s actually my area because I have so many thoughts around it that I’m not sure I can get it all together coherently.
But here goes.
If you thought my previous threads were meandering, strap in!
1) Suicide is not a great barometer for mental health. Suicide is sometimes a rare outcome of mental illness. The vast majority of people with mental illness do not die via suicide, and it’s not even true that the most severely ill die that way. It is notoriously unpredictable.
So whether suicide rates are up or down may or may not have any correlation with overall rates of mental illness or population mental health.
We can add beds and ventilators but there’s only so many people who know how to care for the people in them. You can’t just pull them off the ICU tree. Lord knows you don’t want me in there.
It’s not just the ICU healthcare workers. The non-ICU hospitalists are exhausted. The hospital is busting at the seams at baseline. Now add COVID. Add the people who haven’t been seeing their family doctor regularly for the last year and so aren’t getting preventative care.
I empathize with my colleagues in these other areas.
Because I’m also tired. I think everyone in society is. But it’s definitely true in healthcare.
And in child psychiatry where I am? I’m so exhausted. It’s non-stop. And we were busy BEFORE all this.
Why can't we just vaccinate ourselves out of this quickly enough?
SK has been the BEST vaccinating province so far.
Still, at the current 7-day vaccination rate, we will have vaccinated 75% of adults by June 21st.
We'll get there, but not fast enough to save us in April.
In fairness, I expect that June 21st date to move earlier. The last 7 days has included Easter Long Weekend & many drive-throughs / walk-ins just opened this week.
So we'll get there, but we have to get through April.
Friends, all my ICU colleagues are freaking out right now.
I mean like literally 100% of the ones I know are freaking out.
Not about what ‘might’ happen but what ‘is’ happening.
We’ve been at this long enough to have some Alarm Fatigue, but this is one I wouldn’t ignore.
Once the ICUs are getting hit, we’ve already screwed up. That’s a lagging indicator. One of the problems of using hospitalizations as a measure is you’re always reacting to where you were 3-4 weeks ago.
So these next few weeks are going to be tough.
These variants (UK and Brazil particularly) have taken off. The measures that we thought were enough for COVID-Classic don’t seem to be cutting it. This is spreading fast.
We’re at this really strange split in Saskatchewan right now, where the Ministry of Health and Health Authority are giving wildly different messages about the pandemic.
We got these two letters in the same email from our oldest’s school today:
The first one is from the Ministry of Health. I want you to compare the tone of this one to the one in the next tweet.
This is on the health authority website, linked to on the same email, and is signed by all the medical officers of health in the province.
They are VERY different messaging about the situation we’re in.