Homo = same.
Zygote = of the zygote (fertilised egg).
It means that, for a given DNA sequence, you have the same information on both copies of it. As each copy came from a different parent, it means your parents had the same information as each other.
Zygote = of the zygote (fertilised egg).
It means that, for a given DNA sequence, you have the same information on both copies of it. As each copy came from a different parent, it means your parents had the same information as each other.
https://twitter.com/BradfemlyWalsh/status/1383906038634532864
A common cause is related parents.
If you analyse someone’s entire DNA set, you can get a feel for exactly *how closely related* the parents were. The more events where the sequence is the same in both copies = higher degree of relatedness.
If you analyse someone’s entire DNA set, you can get a feel for exactly *how closely related* the parents were. The more events where the sequence is the same in both copies = higher degree of relatedness.
For some genetic diseases, you need two ‘bad’ copies of DNA to have the disease. The chances of you having the disease are therefore higher if your parents are related.
This explains high rates of genetic disease in families that practice ‘consanguinity’ (cousin marriage, uncle/niece or aunt/nephew marriage etc).
I’ve attended clinical genetics meetings where the level of homozygosity within a child’s DNA indicates very closely-related parents (dad/daughter). It’s very distressing to see.
For clarity: rates are ‘higher’, not necessarily what one would consider absolutely ‘high’.
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