"We need the countries and companies that control the global supply to share financially, to share their doses with Covax...and to share their know-how to urgently and massively scale up the production and equitable distribution of vaccines."
"One way to do this is through voluntary licensing with technology transfer, in which a company that owns..patents on a vaccine licenses another manufacturer to produce its shots..Some companies have done this on a bilateral basis. But such agreements tend to be..nontransparent"
"A more transparent method is for companies to share licenses through the Covid-19 Technology Access Pool, a globally coordinated mechanism proposed by Costa Rica and started by the W.H.O. last year."
"Another option..is to waive intellectual property rights on Covid-19 products through a World Trade Organization agreement that would level the playing field and give countries more leverage in their discussions with companies."
"If this is not a time to take those actions, it’s hard to fathom when that would be."
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"US government can use its ownership of..vaccine patent to push companies to share..expertise..and boost global access to coronavirus jabs, according to..Barney Graham..NIH scientist..who invented..key..technology used in..Moderna and..Pfizer jabs"
"US government patent in question—US patent..10,960,070..— relates to how the spike protein is stabilised in the vaccine, a technique that was developed by..NIH’s Vaccine Research Center. It is..key component of..mRNA vaccine jointly developed by Moderna and the NIH last year."
"'Moderna infringes..NIH’s patent with every dose.. of vaccine it makes or sells in..US,” said Christopher Morten..of NYU..Technology Law and Policy Clinic..'If..US government decides to sue Moderna, Moderna could conceivably owe over $1bn just for..sales through..end of..year.'"
Taiwan: 0.5 per million (11 deaths)
China: 3 per million (4,636 deaths)
Singapore: 5 per million (30 deaths)
Hong Kong: 28 per million (209 deaths)
South Korea: 35 per million (1,802 deaths)
Japan: 77 per million (9,671 deaths)
US: 1,800 per million (582,401 deaths; +800 daily)
New Zealand: 5 per million (26 deaths)
Australia: 35 per million (910 deaths)
UK: 1,900 per million (127,307 deaths)
Nations that successfully suppressed outbreak include both small and large, both island and non-island, and both autocratic and democratic.
Sole relevant parameter for success or failure is whether government took prompt resolute action (success) or whether it did not (failure).
"The world is..failing to develop desperately needed antibacterial treatments, despite..urgent threat of antibiotic resistance..[N]o..antibiotics..currently in clinical development sufficiently address..drug resistance in the..most dangerous bacteria."
"The persistent failure to develop, manufacture, and distribute effective new antibiotics is further fueling the impact of antimicrobial resistance..and threatens our ability to successfully treat bacterial infections"
"Almost all the new antibiotics that have been brought to market in recent decades are variations of antibiotic drugs classes that had been discovered by the 1980s."
Coronavirus origins: how unseen Wuhan research notes could hold the answers
Secrecy has only served to foster distrust among the international scientific community – and fuel speculation that Sars-Cov-2 escaped from a lab scmp.com/week-asia/heal…
"Koblentz said the search should include an independent audit of all labs in Wuhan working on bat coronaviruses and researching Sars, given the deaths and global disruption caused by the pandemic, and most importantly the threat of a repeat."
"Koblentz, the biosecurity specialist, said it was unusual for (WIV) database to be taken offline and never restored, as cybersecurity breaches were usually fixed after companies or government agencies detected a hacking attack."
"[Under Trump swamp creature and former Emergent consultant Robert Kadlec,] Emergent..became the main U.S. location for manufacturing Covid-19 vaccines developed by Johnson & Johnson and AstraZeneca"
["I]nternal documents and interviews..depict a factory operation that was ill-equipped to take on such a mammoth manufacturing task, despite Emergent’s having received a $163 million federal contract to improve the facility"
"Audits and investigations—including ones conducted..by Johnson & Johnson, AstraZeneca,..federal agencies and Emergent’s own quality evaluators—found..Emergent had not followed..basic industry standards..and identified repeated shortcomings in efforts to..prevent contamination."
"An oversight board created to scrutinize research that would enhance highly dangerous pathogens did not review..NIH grant that funded..lab in Wuhan, China, to genetically modify bat-based coronaviruses."
"NIH subagency that awarded the grant to the nonprofit group EcoHealth Alliance to study Chinese bat coronaviruses opted against forwarding it to the P3CO committee"
"Had EcoHealth’s grant been subjected to P3CO review, an HHS panel would have independently evaluated the grant and, if necessary, recommended additional biocontainment measures to prevent potential lab leaks — or even recommended that the grant be denied entirely."