Eric Feigl-Ding Profile picture
May 7, 2021 15 tweets 5 min read Read on X
SCHOOL #COVID FACTORS—

Pandemic theatre: Desk plexiglass shields (even increases risk—possibly disrupting ventilation).

No effect: Same teacher, reduced class size.

Good: Masking (teachers & kids), daily symptom screening, no extracurriculars, cohort.🧵
science.sciencemag.org/content/early/…
2) “School-based mitigation measures are associated with significant reductions in risk, particularly daily symptoms screens, teacher masking, and closure of extra-curricular activities.”
3) “A positive association between in-person schooling and COVID-19 outcomes persists at low levels of mitigation, but when seven or more mitigation measures are reported, a significant relationship is no longer observed.”
4) “Among teachers, working outside the home was associated with an increase in COVID-19-related outcomes, but this association is similar to other occupations (e.g., healthcare, office work).”
5) (A) Number of survey respondents reporting a school age student in the household by county. (B) Percentage of households with school age children reporting any in-person schooling by county, excluding counties with fewer than 10 responses (excluded counties in dark grey).
6) (C) Percentage of households reporting a child in in-person schooling who report full-time in-person schooling, excluding counties with fewer than 10 reporting in-person schooling.
7) (D) Average number of school-based mitigation measures reported for children with in-person schooling, excluding counties with fewer than 10 reporting in-person schooling
8) Odds ratio of COVID-19-related outcomes associated with full- and part-time in-person schooling by outcome and grade level, compared to individuals with children in their household not attending in-person schooling
9) “After adjusting for county-level incidence & other individual- & county-level factors, living in a household with a child engaged in full-time in-person schooling is associated with a substantial increase in the odds [1.38, 95% CI 1.30-1.47] of reporting COVID-19 like illness
10) “…CLI, fever of at least 100°F, along with cough, shortness of breath, or difficulty breathing), loss of taste or smell (aOR 1.21, 95% CI 1.16-1.27), or a positive SARS-CoV-2 test result within the previous 14 days (aOR 1.30, 95% CI 1.24-1.35) “
11) “When stratifying by grade level (restricted to households reporting children in a single grade strata), we find that the strength of the associations with full-time schooling increases with grade”
12) For students engaged in any form of in-person learning, the most common mitigation measure reported was student mask mandates (88%, unweighted), followed by teacher mask mandates (80%)…”
13) “…restricted entry (e.g., no parents or caregivers allowed into school) (66%) and extra space between desks (63%) (see table S5 for survey weighted rates).”
14) “There is substantial geographic heterogeneity in the number of mitigation measures reported (Fig. 1D, fig. S7, and tables S5 and S7), with households in South Dakota reporting the least (@KristiNoem?), and households in Vermont reporting the most”
15) Here are the best practice guidelines for safe indoor air for schools, in addition to the above measures.

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More from @DrEricDing

May 30
⚠️Huge—HUMAN RESPIRATORY INFECTION BY BIRD FLU—A third human case of H5 bird flu just diagnosed in a Michigan farm worker. The individual worked on a dairy farm & didn’t wear PPE. ➡️However—“With this case, respiratory symptoms occurred after direct exposure to an infected cow”—including cough and other respiratory symptoms! Thus is the first bird flu case in which an infected individual reported respiratory symptoms. The 2 human cases reported earlier this year experienced only conjunctivitis (pink eye).

💡Why is respiratory illness significant? It means the bird flu virus has somehow evolved to go respiratory. “The significance of respiratory symptoms relates to the possibility of onward spread. In people, influenza transmits via the respiratory route. A person with flu virus in their airways could be more likely to spread the virus — if the virus has the capacity to transmit between humans — than a person with an infection in their eye.”

statnews.com/2024/05/30/bir…Image
2) CDC declares: “this is the FIRST HUMAN CASE of the H5 virus in the U.S. to report more typical symptoms of acute respiratory illness associated with influenza virus infection”.

cdc.gov/media/releases…
Image
3) This is why CDC has adamantly recommended strict PPE for all dairy and poultry farmworkers and veterinarians. But the word is that farms are resisting PPE use. Hence this mess.
Read 7 tweets
May 24
⚠️My god—RAW MILK WITH BIRD FLU CAN SICKEN—Latest raw milk bird flu study found insanely worrying results. Plus pasteurization heating doesn’t neutralize all bird flu virus!

📌Mice who drank raw milk infected with H5N1 got very sick! And starting from day 1.

📌Finally, 72 degree Celsius pasteurization heated milk did not neutralize the bird flu virus in milk—they used the heated milk with the virus to infect cells successfully.

This is EXACTLY the nightmare that me and @RickABright predicted & worried about!
nejm.org/doi/full/10.10…Image
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2) Furthermore, raw milk with the bird flu virus can survive refrigeration for several weeks! Image
3) “Heat treatment at 72°C was performed, with the default settings of the PCR thermocycler (i.e., preheated lid at 105°C) or with a metal lid (heated to 72°C) covering the PCR block (see the Supplementary Appendixfor details). After heat treatment, samples were inoculated into embryonated chicken eggs or Madin–Darby canine kidney (MDCK) cells for virus detection. Under these conditions, heat treatment for 15 or 20 seconds reduced virus titers by more than 4.5 log units but did not completely inactivate the virus”Image
Read 8 tweets
May 21
HIP FRACTURE DEADLIER THAN CANCER for elderly. A new 🇨🇦 study finds only 1/3 of men & 1/2 of women age>=65 still alive 5 years after a hip fracture. In contrast, 5 year cancer survival higher. But we don’t focus on fracture prevention & nutrition enough.
theglobeandmail.com/opinion/articl…
2) By comparison, the five-year survival rate for older adults is 85 per cent for men diagnosed with prostate cancer, 80 per cent for women with breast cancer, and 56 per cent for colon cancer.
3) Broken hips are both the most common and the deadliest (of fractures). Researchers noted that while women have much better survival rates than men after hip fractures, women are also far more likely to break bones in the first place.
Read 8 tweets
May 20
“As unnerving as H5N1’s current spread in cows might be, “I would be a whole lot more concerned if this was an event in pigs’… Swine airways are evolutionary playgrounds where viruses can convert—and have converted—into ones that prefer to infect us.” 🧵
theatlantic.com/science/archiv…
2) “A flu virus that jumped from swine to humans, for instance, catalyzed the 2009 H1N1 pandemic. If there’s a list of riskiest animals for an avian flu to infiltrate, “pigs are clearly at the top,” Webby said”
3) “To successfully spread in a new species, a flu virus must infiltrate that creature’s cells, reproduce inside of them, and then make it to the next host. This H5N1 has managed that feat in several animals, but so far, “we’re actually still dealing with a very avian virus,”
Read 7 tweets
May 16
⚠️NO RARE BEEF!—@USDA suddenly admits (after Q&A pestering) that 120F cooked beef🥩patties experimentally inoculated with H5N1 virus still had surviving virus.

➡️“Cooking to… 120° F did show that there was virus still in the cooked hamburger patty, although at reduced levels." Image
2) Initially the @USDA only stated that no virus survived cooking to 160 F and 145 F. But they didn’t volunteer the 120 F rare cooking temperature results! Only after more questioning did they reveal 120 F virus survival. But so many folks eat rare meat! 🥩 DISCLOSURE CRITICAL!
3) here was the initial USDA press conference announcement. Made no mention of the results for virus levels in beef at lower temperatures.
Read 12 tweets
May 15
Dear Raw Milk drinkers— behold your future:

“West Virginia politician falls ill due to drinking unpasteurized milk after helping pass a law that legalized raw milk.”

eater.com/2016/3/9/11186…
Image
The FDA has completely dropped the ball on stopping raw milk trade.
3) Folks— famous Typhoid Fever outbreak in UK 🇬🇧 — caused by RAW MILK 🥛… legendary case from 1937.

We don’t learn from history do we? We just have to learn the hard way all over?
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Read 8 tweets

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