In an effort to increase my trivia knowledge and call it "studying", I'll start doing 🧵s about how art intersects w/ medicine in a place called neurology!❤️🧠

First one up: Should the Babinski sign be the Botticelli sign?

Short answer: No
Long answer: No, but this is cool 👇🏽
Babinski wrote about the most famous eponym in neurology, the Babinski reflex, on Feb 22 1896.

With only 28 lines he described the abnormal cutaneous plantar reflex and explained how it associates to the pyramidal tract.
bit.ly/3y7vMAA
Although a myriad of pathologies affecting the pyramidal tract can cause the "upgoing toe" with stimulation to the sole of the feet... this finding can be normal in babies while they continue to myelinate their corticospinal tracts.

embryology.med.unsw.edu.au/embryology/ind…
Luckily, 400 years before Babinski described it, artists of the Renaissance period had an obsession with painting cute and accurate babies everywhere

Medieval artists had same obsession but with uglier, older looking babies.
In this painting by Botticelli, Madonna and Child, or better yet Madonna exploring Child Neurology; the Madonna seems to be eliciting the reflex while stroking the bottom of the child's foot with her thumb.

pubmed.ncbi.nlm.nih.gov/2642699/
And although we have all tried to elicit the reflex by using the dull part of our reflex hammer....

It is only through art we can see a Babinski response being induced by the kiss of one of the 3 Magi at the Nativity in the painting "Adoration of the Magi" by da Fabriano.
Here's another one by van der Weyden.

So next time you go to a museum with Medieval - Renaissance - Baroque art challenge yourself to spot a Babinski...

And please someone take me back to Uffizi. 🙏🏽

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More from @MariaMjaleman

Jun 19, 2022
I was recently talking with my students about epilepsy and the atypical presentations auras and seizures can have...

From hallucinations to deja vus, and even ... happiness?? Dostoevsky explains 👇🏽👇🏽

#NeuroTwitter #ArtTwitter Image
Dostoevsky, one of my favourite authors (to whom I owe some of my own most "profound" thoughts) is also one of the most famous literary figures on epilepsy.

Here's a description of Dostoevsky's seizures by a close friend, Strakhov: ImageImage
Although a lot of that description is fascinating, what really catches everyone's eyes is the term✨ecstasy✨.

What could he even mean by that? Thankfully, Doestoevsky himself tells us more about his experiences through the (beautiful) narration of a seizure in "The Idiot": Image
Read 11 tweets
Aug 2, 2021
Do you think creativity can be pathological? 🤔
Neuro says: maybe🧠❤️

What differential diagnosis can you come up for the CC: "new or improved bursts of creativity"? ⚡🔥

(Sorry for the made up schema, don't quote me on this)
#art #neurotwitter
@AaronLBerkowitz first introduced me to the story about obsession, creativity and neurological disease of both Maurice Ravel and Anne Adams.

Let's start at the beginning with Ravel (🇫🇷 1875 - 1937). He was a pianist and composer associated with impressionism.
His most famous work "Bolero" has been described as: "an exercise in compulsivity, structure and—some have suggested—perseveration".

He composed it at the age of 53 while developing prominent apraxia, right-sided motor deficits and aphasia.
Read 15 tweets

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