#tbt This is the graduating class of 1915, chemistry division, Tohoku Imperial University. There, at the end of the 2nd row, is the first woman to achieve a bachelor of science in Japan. Her name was 黒田チカ, Chika Kuroda (1884-1968) & she was the daughter of a samurai...1/5
...Kuroda was an organic chemist & studied natural pigments. As an undergraduate, she studied a purple one, Lithospermum erythrorhizon. When she presented her work on it to the Chemical Society of Japan, she was the first woman to ever do that, too ...2/5 en.wikipedia.org/wiki/Chika_Kur…
..Kuroda studied at Oxford Uni 1921-23, & later joined the RIKEN in Japan, where she determined the molecular structure of shikonin, that purple pigment & then of carthamin. It gives safflower its color: she earned her doctorate with that in 1929..3/5 riken.jp/en/about/histo…
...She studied several other pigments & was awarded the Majima Prize in 1936 by the Chemical Society of Japan. Here she is in 1948. Soon after, she began studying onion skin, extracting crystals that were used to create an antihypertensive drug...4/5
FDA report on the Novavax vaccine questions whether there's a causal relationship for myocarditis/pericarditis after the vax. This 🧵digs into their report, the Novavax response & submission, & rollout data... (1/8)
...FDA report on Friday lists 6 cases in vaxed arms of 2 trials, 4 of which don't have a specific possible alternative cause identified. This was versus 1 in placebo (not injection-related). The 2 trials had ca 27,000 vaxed participants... fda.gov/media/158912/d…
...FDA report expressed concern because a pre-marketing database of ~40,000 had more potential cases, & this hadn't been a pre-marketing safety signal for mRNA vaccines: so to them it raised Q if it could be higher for this vax than for mRNA vaxes...
#tbt This is Toshiko Yuasa, the first woman physicist from Japan. It's 1940 & with her science prospects at home blocked by gender prejudice, she'd managed to get into wartime Paris to do physics research... en.wikipedia.org/wiki/Toshiko_Y…
...The drawcard in Paris was Marie Curie's daughter, Irène Joliot-Curie & her husband Frédéric. Yuasa was inspired by their papers on artificial radioactivity.
Here's Toshiko & Irène at the Joliot-Curie home in 1941... en.wikipedia.org/wiki/Ir%C3%A8n…
...Yuasa was born in downtown Tokyo in 1909, the next-to-youngest of 7 children. Her mother came from a long line of poets, in the family of a renowned 19th century scholar, Tachibana Moribe. Her father was an engineer & inventor who worked at the patent office...
When it hit me that I knew nothing about early women scientists in Ukraine, I went down a mind-blowing rabbit hole...
So hard to pick, but I whittled down to 15 amazing stories of women born before WWII.
Today, part 1, with the first 5 women 🧵 @PLOSabsolutelymaybe.plos.org/2022/04/27/ear…
...This is Maria V. Pavlova (1854-1938), at her desk in the 1920s with fossils. She corrected an error in assumptions about the ancestry of horses...
...Sofia Okunevska-Morachevska (1865-1926) was an activist doctor - the 1st medically qualified woman in the Austro-Hungarian empire, not just Ukraine....
Such terribly sad news: the loss of Chris Del Mar, a giant of the Australian – and global – evidence community.
💔 for Tammy & family.
You'll hear a lot about this wonderful, lovable person & his amazing life ....
...Here's a quick overview from late last year, when Chris was awarded the Order of Australia - one of my faves because of the lovely family photo.... www1.racgp.org.au/newsgp/profess…
...I want to add to the remembrances & accolades for Chris, memories of a specific stream of his life - patient empowerment. From back in the early 2000s when we used to use this photo. He was the Chair of the Board of the consumer health information NGO I headed back then...
1st Covid human challenge trial results shows it is feasible: 34 people were inoculated with a very low dose. It was enough to infect 18 people (53%) & 89% of them developed symptoms ...🧵 researchsquare.com/article/rs-112… HT @HelenBranswell
..Viral shedding quantifiable within 40 hours. They concluded up to 44% of infections would happen before virus can be detected. Results support 10-day isolation periods & professionally-administered LFA/RAT was "highly reliable in predicting the disappearance of viable virus"...
...The people were 18-29 years old, & stayed in individual negative pressure quarantine rooms. No safety signals in these first 28 days of follow-up. (They'll follow them for a year)...
Great relief: it's a critical vax for the COVAX supply. Protein subunit vax, with a Dynavax adjuvant & alum. Records on it: zotero.org/groups/2528572… ...1/n HT @lutl88
...The trial has 30,128 participants in Philippines, Brazil, Colombia, South Africa, Belgium. All infections sequenced were variants. Because of vax programs in these countries, not many older people...2/n
...For people without previous SARS-CoV-2 infection, 207 tested positive & 146 of these sequenced so far. 73% were Delta (most of them), Mu, & Gamma...3/n