1/"Aim 3. In vitro and in vivo characterization of SARSr-CoV spillover risk, coupled with spatial and phylogenetic analyses to identify the regions and viruses of public health concern. We will use S protein sequence data, infectious clone technology, in vitro and in vivo...
2/infection experiments and analysis of receptor binding to test the hypothesis that % divergence thresholds in S protein sequences predict spillover potential. We will combine these data with bat host distribution, viral diversity and phylogeny, human survey of risk behaviors...
3/and illness, and serology to identify SARSr-CoV spillover risk hotspots across southern China. Together these data and analyses will be critical for the future development of public health interventions and enhanced surveillance to prevent the re-emergence of SARS or...
Thanks to @jimgeraghty who has endured my tags on every point which I find salient to his virus interest in the Twittersphere - I owe you a hot chocolate for your patience.
'NBC News states, “scientists say that scenario is unlikely on its face, because animal-to-human transmission of viruses are common, while lab accidents are relatively rare.”'
Geraghty: 'the word “relatively” is doing a lot of work in that sentence'
"In 1979, the city of Sverdlovsk in the Soviet Union suffered a sudden and mysterious outbreak of anthrax, sickening 94 people and killing at least 64 of them. The Soviets blamed tainted meat." @ydeigin