For months I have been advocating for CDC and FDA to issue guidance on second doses for the millions of people who got the single dose J&J vaccine.
Now we have more data. I urge them to act. The delta variant doesn't respect one dose. nytimes.com/2021/07/20/hea…
Now we have more data. I urge them to act. The delta variant doesn't respect one dose. nytimes.com/2021/07/20/hea…
One dose of Pfizer and Astra Zeneca didn't cut it. There was nothing special about J&J that would have allowed it to be uniquely effective. We knew this months ago.
One dose is not enough. One dose is not = fully vaccinated.
One dose is not enough. One dose is not = fully vaccinated.
Short term protection which is what was studied in the randomized trials was good. So was it after one dose of Astra Zeneca.
But immunology 101 is that a second exposure to same antigen allows more class switching and more effective and durable response.
But immunology 101 is that a second exposure to same antigen allows more class switching and more effective and durable response.
In any case, now that delta is in full swing with 83% of COVID in USA, it would be very risky to do nothing.
Given what we know, I really urge the CDC or FDA to act with a recommendation for a second dose.
Given what we know, I really urge the CDC or FDA to act with a recommendation for a second dose.
Based on available data 1 dose of Pfizer would be a great choice for 2nd dose. We know it works & is safe from Astra Zeneca/ Pfizer mix match experience.
We need to protect those who did what we recommended at the time which was to get whichever vaccine they were offered first.
We need to protect those who did what we recommended at the time which was to get whichever vaccine they were offered first.
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