An oversimplification of the science
1. In first few days of illness viral loads (VL) r similar bet vaxxed & unvaxxed
2. NHS study only captured the early few days of symptomatic persons.
3. 90-97% mRNA and 70% AZ vaxxed are asymptomatic!
3. Though similar VL are they viable in vaxxed vs unvaxxed?
4. VL in vaxxed maybe rendered non-viable and/or less infectious. by neutralising antibodies
5. VL in unvaxxed are replication competent virus
6.    PCR cannot differentiate between them threadreaderapp.com/thread/1424780…
7. We need a replication assay
8. After few days the VL drops faster in vaxxed below the contagious level.
9. Vaxxed persons overcome infxn faster-period of infectiousness shorter
10. Play safe scenario-vaxxed & PCR positive should isolate during 1st wk of infxn
11. Get vaxxed!

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More from @drmusanordin

7 Aug
Transcript of the conversation in question.

facebook.com/ResetMalaysia.…

Minutes 57:00-57:50
Dr. Abu Hafiz:
Moderna telah pun diluluskan di USA dan banyak negara yang lain, tetapi seperti mana yang Dato' sebutkan, NPRA masih belum lagi meluluskan. (1)
Apa sebenarnya masalah kepada kita dalam menerima vaksin-vaksin yang telah diluluskan di dalam negara-negara maju? (2)
Dato' Dr. Musa Mohd Nordin:
Moderna telah diluluskan pada bulan 12 last year (US), 8 months ago. Kita luluskan dulu Pfizer, lepas tu Sinovac, lepas tu AZ. fda.gov/emergency-prep…
Read 4 tweets
6 Aug
DG MOH 1991-2001:
“many questions had been raised by the suspension of Parliament, adding that the rationale behind it was not clear to him”
“must ensure that all his decisions were made with professionalism rather than political considerations.
freemalaysiatoday.com/category/natio…
God gave him a golden opportunity to save 32 million people.
To save a whole nation in crisis and engulfed in a deadly pandemic.
Instead he chose to save one person.
An unprecedented dereliction of trust & responsibility.
Dishonouring a doctor’s oath Primum Non Nocere
Parlimen:
1. 90% vaccinated ie Herd Immunity

2. Positive rate 0.8% Very much less than WHO 5% threshold

Parlimen one of the safest place on earth after NZ!

Science: Parlimen boleh bersidang
Read 7 tweets
29 Jul
This is more fun than cows in condominium.
The parliament is convulsing in pandemonium.
The speaker is behaving like foetid meconium.
His spine needs fixing with rods of titanium.
Sidang Parlimen sudah dicuri
PM dan Speaker dah cabut lari
DiJepun kalau Raja diingkari
Kabinet semua wajib harakiri
This is truly a historical moment
Actually it’s such an embarrassment
Kesian! DSAI  & PH are locked in parliament
PM takut he take over government :)
Read 8 tweets
23 Jul
Our 3rd visit to CAC Stadium Melawati 23/6/202 @DrDzul
We were expecting to see a smaller crowd since KKM on 14/6 declared Cat 1&2 DO NOT need to go to CAC
They will be digitally monitored from home
We were disappointed!
By 6am the crowd was piling up!
The CAC expect about 5K!
Lorong diluar khemah hadir diCAC untuk potong gelang pink.
Mereka kini beratur sampai hujung jalan 550m!
Yang dibawah khemah -6 saluran kes baru covid.
Saya agak 90% covid kategori 1-2
Mereka tak sepatut ada disini.
Boleh dipantau dari rumah
Tengok baby tu-KKM tak kesian ke?
9 hari telah berlalu tetapi KKM masih lagi tidak operasikan pemantaun digital dirumah!
Greater Klang Valley Task Force (GKVTF) gagal untuk operasikan kaedah baru ini!
Pimpinan KKM mungkin sibuk siapkan protokol cantik diPutrajaya selama 9 hari … atau mungkin sibuk selfie?
Read 9 tweets
21 Jul
PM, NSC, KKM, MOSTI putting all their eggs in the Vaccine Basket!
No one is doubting importance of ramping up V-rollout.
BUT it must NOT be done at the expense of FTTIS.
Protection for individual is at least 5 weeks after 1st dose.
Protection for nation earliest 4th quarter (1) ImageImage
Meanwhile we must ramp-up Testing!
We must detect the infected, isolate them and stop them from becoming outbreaks or clusters
Ramp-up Testing to drop Positive Rate <5%
Conservative estimate of daily test is 1% of the unvaccinated population Image
We’ve vaccinated 5 Million
Test required = 1/100 X 27 Million = 270,000
Tests from 19/7-21/7 =107,495 (11.06%)
Positive rate since May 2021 >5%
We can do 350-400K vaccinations daily but not Testing. Why?
Testing tak glamor berbanding dgn Vaksin ke?
bfm.my/podcast/evenin…
Read 11 tweets
18 Jul
In influenza, hemagglutination inhibition (HAI) titer of 1:40 is thought to provide 50% protection from infection
This assay is used to predict Vaccine Efficacy (VE) and to assist in the annual reformulation of seasonal influenza vaccines.
 ema.europa.eu/en/documents/s…
Neutralizing antibody levels is highly predictive of protection in COVID
This apart from T cell responses or B cell memory responses as additional potential correlates of protection.

nature.com/articles/s4159…
Analysis of the relationship bet in-vitro neutralization levels & clinical protection suggested:
Neutralization level for 50% CLINICAL protection = 20.2% of mean convalescent level (14.4–28.4%)
For 50% protection from SEVERE infection = 3% of mean convalescent level (0.7–13%)
Read 8 tweets

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