COPTIGATE - 3D CHESS EDITION

How the worst design flaw in human history (that is impacting your health) is even WORSE THAN YOU THINK.

(thread)

#COptiGate Image
Before we continue, if you didn't had the chance PLEASE head to the original thread, and don't forget to press the "Show replies" button at "the end" of the thread because, I added extensively to the original thread (press it multiple times!).

#COptiGate
Hi again,
First, deep gratitude to @Kevin_McKernan (Check his BIO!) for his comments on the original thread. If only I have known 1% about genetics of what he already forgotten!

After summarizing his comments we can proceed to the 3D chess.

#COptiGate
As I said in the original thread, Pfizer, Moderna, and Janssen implemented a genetic code change (2P) in order to stabilized the spike protein their product creates, We know that Pfizer & Moderna also implemented letter substitution, so let's recap that topic.

#COptiGate
Remember, a genetic code is made of letters (nucleotides), grouped together in groups of 3 we call codons.

In order to bypass protection mechanisms in the human cells that prevent viral replications, some manufacturers decided to trick to use letter substitution.

#COptiGate
Pfizer and Moderna replaced all the U genetic letters with N1-methylpseudouridines (Ψ), or in short PSI, to allow "protect it from the immune system".

The problem is it causes it causes translation errors when the ribosomes process the code.

pnas.org/content/116/46…
#COptiGate
Or, in other words, because the manufacturers have decided to use letter substitutions they have caused translation errors, mutations, variants, or whatever you like to call them.

#COptiGate
When scientists tried to train the immune system using optimized codon segment of the SARS_CoV_2 virus, a nonstructural protein, it didn't work. Optimization "broke" it.

biorxiv.org/content/10.110…

#COptiGate ImageImageImage
Again the warning:
"protein function can be compromised even by a single synonymous codon substitution...and protein expression...may hinder proper folding".

Or in our case - your body might face a protein that we don't know what it do.

#COptiGate Image
You can learn more about concerns surrounding the mRNA products and the the dangers that can rise through them by this interview with geneticist Dr. Alexandra Henrion-Caude.

#COptiGate
bitchute.com/video/4C3NLaKZ…
Finally, Kevin reminded us that the SARS_CoV_2 has a fusion of multiple wild viral components (such as furin cleavage site), plus a human optimized spike, via greater synonymous codon vs. this virus "relatives" in the wild.

academic.oup.com/ve/article/6/1…

#COptiGate
THIS BRINGS US TO THE 3D-CHESS!!!

In an article called "Genetic Code Complexity Just Tripled" published in "Evolution News" on April 21, 2017, describes the findings of two scientists from the University of Utah which breaks a genetics dogma.

evolutionnews.org/2017/04/geneti…
#COptiGate
Authors again confirmed what I've already covered in the 1st thread.

#COptiGate Image
THEIR BIG DISCOVERY was that if they changed a codon on one side of a faulty codon it resulted in a 10-fold increase in protein activity, Changing the codon on the other side resulted in a 20-fold decrease, and changing both produced a 35-fold increase.

#COptiGate Image
So a codon, which are 3 letters, seems to be a part of a superstructure of 3 codons, one before it and one after it, and they all influence each other.

#COptiGate
Implications:
1) You can't just do a do a change in a lab environment on a codon and assume your change will work on humans. It can explain why lab experiments working on one gene fail when moved to humans.

#COptiGate Image
2) From an evolutionary perspectives, "the difficulty for natural selection would be in finding codon optimization for a given gene" selection pressure on a single codon requires 844,596,301 codon combinations.

#COptiGate Image
This means that the chances of the SAR_CoV_2 being a result of an evolutionary pressure seems inconceivable. The added features, the optimized for humans spike protein... all in a virus that was supposed to origin from bats and via evolutionary pressure?

#COptiGate
BACK TO THE 3D CHESS.

AS FAR AS I KNOW the codon optimization which is used by manufacturers (Pfizer, AZ, Moderna, Jannsen etc.) do not take into account the the triplet-of-triplets relationship, meaning THEIR CODON OPTIMIZATION CAN INTRODUCE UNPREDICTABLE FEATURES!

#COptiGate
SUMMARY:
On top of all the possible problems that can introduced due to the optimization, there is an inability to foresee the real impact of this optimization due to the inter-dependency of codons.

Welcome to Jurassic Park, the Codon Optimization edition.

#COptiGate
FINISHED
#COptiGate

Don't forget to press the "Show replies" button below!
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More from @eh_den

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To understand what member states got dragged into these horrible agreements, let's go back to the agreement between the commission & member states on producing vaccines, annexed to EC decision C(2020) 4192 from the 18th of June 2020.

ec.europa.eu/info/sites/def…

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(remember - always use "show replies" at the end)

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On Friday @arad_nir, Israeli journalist, has exposed that according to Philip Dormitzer, Pfizer's Vice President and Chief Scientific Officer (Viral Vaccines), Israel acts as "a sort of a laboratory", and that its MoH is exclusively using the Pfizer product.

#PfizerLeak
@arad_nir pointed out that this was in direct conflict with the statement of Dr. Sharon Alroy-Preis (Israel's director of Public Health Services in the MoH) given only 3 weeks ago, when he asked her why does the Israeli citizens are trapped by the Pfizer contract.

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Welcome to 21st century totalitarianism, EC style.

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#PfizerLeak
On the 17th of June 2020 the EC declared the "EU Strategy for COVID-19 vaccines".

It was based on two pillars:

1) "Securing sufficient production of vaccines in the EU through Advance Purchase Agreements (APAs)" with manufacturers.

#PfizerLeak
eur-lex.europa.eu/legal-content/…
2) Adapt the "regulatory framework ...making use of existing regulatory flexibility to accelerate the development, authorisation and availability of vaccines while maintaining the standards for vaccine quality, safety and efficacy."
#PfizerLeak Image
Read 84 tweets
2 Sep
COPTIGATE - THE SUMMARY EDITION!
(thread)

Highlights from my writing on the topic of codon optimization, for those who have never heard about it before (or for those who wish to share it with others).

#COptiGate
Before you bombard experts (e.g. @RWMaloneMD) with endless requests to comment on the validity of what I write, please read this thread, then go to the previous threads (links below), and see the references I use.
There is MUCH MORE INFORMATION in my previous threads!

#COptiGate
1) Inconsequential (“silent”) mutations are known as synonymous mutation.
2) Synonymous mutations contribute to cellular processes which are determining protein structure and function.
3) Synonymous mutations influence protein folding.

#COptiGate
Read 32 tweets
30 Aug
@plecbe @wimremes Hi!
Stats:
Brussels/Belgium, 26/8/2021:
20/57 admissions
25/75 releases
191/602 in hospital
68/182 in ICU
37/98 on ventilator
# beds in Brussels: 7070. St. Jin: 548, ~8%, w/statistically ~3 PATIENTS ON VENT.

NEVER TRUST THE MEDIA!

en.wikipedia.org/wiki/List_of_h…
datastudio.google.com/embed/u/0/repo…
@plecbe @wimremes More:
According to the article, only 64% of the adult population in Brussels are FULLY vaccinated. Since there is almost same # of vaccinated and non-vaccinated on ventilators in Israel, this statistic just doesn't add up.

+: how many on vent has 1 shot?

gov.il/en/departments…
@plecbe @wimremes UNVACCINATED POPULATIONS

Most people fail to realize that in many times SICK PEOPLE under Immunosuppressive Therapies ARE NOT ALLOWED TO TAKE THE COVID19 VACCINE due to their condition.

Here is BC's Centre for Disease Control document on the topic:

bccdc.ca/resource-galle…
Read 4 tweets
28 Aug
REVERSE ENGINEERING: WHAT DO WE KNOW ABOUT THE GENETIC CODE WITHIN THE PFIZER VACCINE?

(thread)
What does the mRNA code in the Pfizer vaccine tell us about the genetic design decisions, its safety, possible impact on our health, and the "quality" of FDA BLA approval?

#COptiGate Image
This is going to be A LONG thread; I will review the code after the introduction. As usual (with my posts), please use the "show replies" option multiple times to unveil the whole thread.

OK, let's start!

#COptiGate
The FDA's approval to Pfizer's Biological License Application (BLA) stated "...our review of information submitted in your BLA application...did not raise concerns or controversial issues that would have benefited from an advisory committee discussion."

REALLY ???

#COptiGate ImageImage
Read 60 tweets

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