This could be a seminal paper explaining many of the thrombotic and myocarditis adverse reactions to the Covid vaccine. academic.oup.com/cid/advance-ar…
When the vaccine is injected intramuscularly, assume it behaves as expected and drains via the lymphatic system. However, a careless injection could result in vaccine taken up by small veins or venules. Now some is intravascular and travels to the heart, lungs, vessels and brain
The spike protein could be expressed by the endothelial cells causing microthrombi, pulmonary thrombus, stroke or VITT. The spike protein could also cause myocardial damage.
Also possible, the spike protein could be expressed on the myocardial cells if the 2nd dose is intravascular, resulting in IgG mediated damage to the cells. The IgG response would have been primed by the 1st dose. A viable hypothesis? @gerdosi@JeanmarcBenoit
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The data coming in on Covid breakthrough cases bears watching. Overall Covid IFR is 0.15 to 0.3% per Ioannidis. Vaccines are supposed to prevent severe illness and death. However at least 2 states have provided details on breakthrough cases.