Realistic article by @DLeonhardt walking us through risks to the vaccinated of the delta variant. "In Britain, many people have become comfortable with current Covid risks. Vaccines make serious illness rare in adults, and risks to young children are low"
nytimes.com/2021/09/07/bri…
"There's a feeling we can finally breathe, get back to what we have lost" in UK "Many Americans feel differently. Our level of Covid anxiety is higher, especially in communities that lean to the left politically. ..But at least one part of the American anxiety does seem to have
"become disconnected from the facts in recent weeks: the effectiveness of the vaccines...". Despite recent poll showing many vax'd Americans still think they can get very sick, "In reality, the risks of getting any version of the virus remain small for the vaccinated"
"and the risks of getting badly sick remain minuscule...In Seattle on an average recent day, about one out of every one million vaccinated residents have been admitted to a hospital with Covid symptoms. That risk is so close to zero that the human mind can’t easily process it".
I know it is difficult as being bombarded with fear at every turn (& perhaps the good news about the vaccines seems too good to be true) but I hope @NYT with its excellent reporting can convince you that no need to be scared if vax'd or doubt effectiveness of vax if unvax'd
UK had similarly difficult time as we with COVID but has high rates of vax, messages the (valid) optimism about the vax, kept schools open, & now fear subsiding with incorporation of low level endemic COVID as fact of life with other public health concerns; hope we can too
I am sure left-leaning areas will take 3rd booster more readily if offered to immunocompetent (instead of to high-risk groups like elderly, multiple medical conditions); have mask mandates longer; & close more schools but vax confidence will win out in US too as it did in EU
@DLeonhardt in this brilliant reporting goes a long way to hopefully reverse this trend that the "messaging over the last month in the US has basically served to terrify the vaccinated and make unvaccinated eligible adults doubt the effectiveness of the vaccines?"
History of infectious diseases tells us immunity is only way to get through pandemic. Vax cause immunity (and so does spread of delta in unvax'd adults). Good messaging on our part like this @DLeonhardt piece could help vaccine uptake even more
leaps.org/how-long-do-co…

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Monica Gandhi MD, MPH

Monica Gandhi MD, MPH Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @MonicaGandhi9

15 Sep
This is likely study (just got released) pushing booster conversation in US for >60 (of note, booster discussion most relevant to places with high circulating virus due to low vax rates, not urgent in EU now). Data from Israel -not an RCT-
nejm.org/doi/full/10.10…
but decision made in Israel to boost those >60 whose 2nd shot >5 months ago on June 30. This is data from July 30-August 31, 2021, from Israeli Ministry of Health database comparing those who had 3rd shot >=12 days before to those who had not. No matching on co-morbidities etc. Image
>= 12 days after booster, rate of confirmed infection lower (factor 11.3) in booster group than in nonbooster group as was rate of severe illness (factor of 19.5) . Better protection later on. Likely to push US to boost >60 while cases will circulating with our low vax rate
Read 4 tweets
15 Sep
Don't have time to analyze this now but publicly-available documents that the FDA will review for their decision on boosters on Friday are now available here if you want to take a look
fda.gov/media/152176/d…
FDA seems unconvinced so far but we need to go through it bit-by-bit and make a clean decision by Friday so will analyze the studies for you later today
endpts.com/as-booster-sho…
However, this India study showing declining antibodies after vaccination is not really showing anything but how the immune system works. Antibodies wane to avoid your blood becoming the consistency of a milkshake but memory cells make more
reuters.com/world/india/in…
Read 5 tweets
14 Sep
Discussing balance, nuance, risk factors for COVID (before vax or even after vax, including heart disease, obesity, etc.) is important. Episode with @DrTomRifai & @DrDavidKatz about balance, collateral damage of pandemic (ok to say that word) and 1918 pandemic
For instance, even fetal stress in 1918 due to health, lower attainment of adulthood income, and occupational fulfillment led to shorter lifespans. Similar to discussions of long-acting impacts of our prolonged school closures in US last year (balance)
read.dukeupress.edu/demography/art…
Cohorts born during 1918 pandemic and in its aftermath exposed to stress, which leads to inflammation which has long-term health effects (on cancer, cardiovascular disease, etc.)
ajph.aphapublications.org/doi/10.2105/AJ…
Read 6 tweets
13 Sep
A lot on boosters & immunity (the higher the better; obviously in a surge, immunity goes higher but vaccination rates up too) this week with a summary on @MdMashup
mashupmd.com/weekly-expert-…
Nice paper this morning from Lancet on "Considerations on boosting COVID-19 vaccine immune responses". "The vaccines that are currently available are safe, effective, and save lives. The limited supply of these vaccines will save the most lives if made ..
thelancet.com/pb-assets/Lanc…
available to those who are at appreciable risk of serious disease and have not yet received any vaccine. Even if some gain can ultimately be obtained from boosting, it will not outweigh the benefits of providing initial protection to the unvaccinated" [ and tamping down variants]
Read 4 tweets
11 Sep
NOVAVAX vaccine: Want to do a thread on this more traditional vaccine as it involves a protein (spike protein) + an adjuvant instead of genetic material for you to code for spike protein. Remember, we have >9 vaccine candidates worldwide
6 of the vaccines involve the spike protein (5 have you produce the spike protein from genetic code; 1 - Novavax- is the spike protein + adjuvant) and 3 are inactivated whole virions. Spike protein attaches virus to cell
Here are the 6 that involve the spike protein including Novavax so let's explain the latter next and data to date
Read 10 tweets
7 Sep
As you know, multiple models showing cases declining in two months with worst of this behind us then but we can get there in 2 ways: 1) delta spreading to unvaccinated eligible adults leading to natural immunity (happening anyway); 2) increasing vaccination which will accomplish
same without same hospitalization/death rate. Delta leaves immunity in its wake…One analysis that assumes that the delta variant is so contagious that it will infect adults in the US (over 17) in the US predicted the current decline in the South and now predicts that the states
most vulnerable to increasing cases and hospitalizations are Michigan, Wisconsin, Minnesota and Iowa due to their relatively lower vaccination rates and the fact that it appears that delta is just taking hold in these states. Places like Northeast with high rates of vaccination
Read 5 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!

:(