Prof. Jose-Luis Jimenez Profile picture
Sep 9, 2021 23 tweets 10 min read Read on X
1/ AIRBORNE TRANSMISSION OF RESPIRATORY VIRUSES: THE COMIC VERSION

Supplementary multimedia prepared by lead author @ChiaWang8 to our recent @ScienceMagazine peer-reviewed paper

science.org/doi/10.1126/sc…

@kprather88 @linseymarr @zeynep @Lakdawala_Lab @zeynep
2/ The cast of characters: aerosols & droplets
3/ So what are aerosols?
4/ How can aerosols infect through airborne transmission? (by inhalation)
5/ What is the main difference between aerosols and droplets?
6/ How long can virus-containing aerosols linger in the air?
7/ Virus-containing aerosols are impacted by airflow and ventilation
8/ Racing with time: how long do infectious viruses survive in aerosols?
9/ Filters work well to remove infectious aerosols from the air (commercial HEPA or cheaper fan + filter like Corsi-Rosenthal box):
10/ Solar radiation and artificial UV light disable aerosols by damaging their genetic material. (But ventilation and/or filters are preferable to artificial UV whenever possible)
11/ Virus-laden aerosols can enter and deposit in the bronchiolar and alveolar regions of the lungs (also in the nose and upper respiratory tract):
12/ ACE2 is the cell entry receptor that binds and guides SARS-CoV-2 to invade cells
13/ Crowding indoors is a key element for superspreading events
14/ Why did so many people get infected despite mask wearing? (not wearing it tight to the face, or low quality filter)
15/ Surface disinfection CANNOT block airborne transmission (and is a waste of time and money):
16/ Plexiglas barriers may trap higher concentrations of aerosols! (and INCREASE, rather than decrease, transmission of the virus)
17/ How to stop airborne transmission?
- Keep distance (helps but not enough by itself)
- Ventilation, filtration (+UV in some cases)
- Masks w/ attention to fit to the face
- Avoid indoor crowding
18/ More information:

- Our scientists'FAQs: bit.ly/FAQ-A
- @ScienceMagazine review: science.org/doi/10.1126/sc…
- @TheLancet paper: thelancet.com/article/S0140-…
- @ScienceMagazine paradigm shift paper: science.org/doi/full/10.11…
- Transmission estimator: bit.ly/c-est
19/ There are many requests to translate to other languages. So far they are only in English, but I am inquiring if we can make the editable files available, will post here if so.
20/ If you want to download all the comic images at once, they are available in this folder:

drive.google.com/drive/u/0/fold…
21/ And for people more inclined to learn about the details, check out the literature references etc., this thread explains the @ScienceMagazine paper in more detail:

22/ A powerpoint version can be downloaded from this folder from @chiawang (it is the file that ends in "pptx"):

drive.google.com/drive/folders/…
23/ TRANSLATIONS: if interested in translating the comics, pls complete agreement in folder below, & send it to @ChiaWang8 at chiawang@mail.nsysu.edu.tw:

Translation to Indonesian, Thai, Dutch, and Sinhala is already underway. Help for others needed

drive.google.com/drive/folders/…

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More from @jljcolorado

May 8
1/ "After four years of fighting about it, @WHO has finally proclaimed that viruses, including the SARS-CoV-2 virus that causes COVID, can be spread through the air"



By @maggiemfoxscientificamerican.com/article/a-figh…
2/ "It took four years to get here because some leaders in public health, medicine and science clung too tightly to precision and semantics"

"One particular moment of shame came on March 28, 2020, when WHO tweeted: “FACT: #COVID19 is NOT airborne.”

3/ "Words matter. When people heard that COVID might spread on surfaces, they wasted time wiping down groceries. People who misunderstood airborne spread needlessly wore masks on outdoor walks and veered off sidewalks to avoid their neighbors."
Read 7 tweets
Apr 18
1/ @WHO has published a report on updated terminology for disease transmission

I've seen some debate about it. My take:

- Terminology itself is ok. Big progress
- But no recommendations of how to protect!

Report:

Press release: who.int/publications/m…
who.int/news/item/18-0…
2/ The report was likely the result of intense pressure on @WHO during the pandemic:

- They denied that #COVIDIsAirborne on March 2020
- They finally accepted it 2 years later

nature.com/articles/d4158…
@WHO 3/ To their credit, @WHO did invite some of their critics to be part of the committee.

What was the terminology before. In medical circles:

- droplet transmission: if it happened in close proximity, or if particles were > 5 microns

- airborne transmission: if it happened far
Read 34 tweets
Mar 28
1/ New paper in @ScienceMagazine: "Mandating Indoor Air Quality for Public Buildings"

Explaining current status of indoor air quality standards (in short: bad or non-existent), the huge health benefits that would arise from them & proposing a path forward
science.org/doi/10.1126/sc…
Image
2/ "People living in urban & industrialized societies, which are expanding globally, spend more than 90% of time indoors, breathing indoor air (IA)."

"Most countries do NOT have legislated indoor air quality (IAQ) performance standards for public spaces"

science.org/doi/10.1126/sc…
3/ "Few building codes address operation, maintenance, and retrofitting, and most do NOT focus on airborne disease transmission."

"We propose that Indoor Air Quality (IAQ) standards be mandatory for public spaces"

science.org/doi/10.1126/sc…
Read 14 tweets
Oct 4, 2023
1/ Checking the ventilation by measuring CO2 as I travel to the #AAAR2023 conference

@RideRTD bus to Denver airport. Bus route had started 3 min before I got in, already 1500 ppm

Typical of these @RideRTD buses, poor ventilation Image
2/ Not getting any better as time passes in the @rideRTD bus to the airport...

7% of the air is being re-breathed, it has already been in someone else lungs when each of us breathe it. Image
@RideRTD 3/ Given the often poor-to-mediocre ventilation in US transportation systems, I wear N95 masks (not KN95, less good)

In this case @3M VFlex, which I tested at 99.99% filtration for myself

It also stays sealed when I talk, doesn't distort my speech (& add to my Spanish accent) Image
Read 14 tweets
Oct 2, 2023
1/ Video de mi presentación sobre "Transmisión de enfermedades por el aire: cómo funciona, por qué se malentendió, y cómo reducirla"

como parte de la presentación del libro de ventilación de @aireamos

2/ Las diapositivas se pueden bajar de este enlace.

(Son de una charla más larga así que tienen más detalles, pero están todas las de la presentación de @Aireamos)

drive.google.com/file/d/1Bs0RRG…
@aireamos 3/ Miguel Ángel Campano @MA_Campano y @Aireamos han sido los motores del libro de ventilación:

Read 4 tweets
Sep 1, 2023
1/ Measuring CO2 indoors in a 10 day trip from US to Europe & back

Bus @RideRTD to Denver airport, poorly ventilated as usual.

We have not left town yet! In previous trips it kept increasing, we'll see this time. Image
2/ For background on what CO2 indoors indicates and more details, see

TLDR:
- We exhale 40000 ppm CO2
- Outdoors: 420
- Each 400 extra ppm indoors = 1% extra rebreathed air
- CO2 makes us dumber, indicator of virus & pollutants. Does not capture filteringdocs.google.com/document/d/e/2…
3/ Or by reducing recirculation. Some recirculation is ok if well-filtered, saves energy.

Energy-recovery ventilators allow ventilating well with limited energy use.

Read 18 tweets

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