Prof. Jose-Luis Jimenez Profile picture
Sep 9, 2021 23 tweets 10 min read Read on X
1/ AIRBORNE TRANSMISSION OF RESPIRATORY VIRUSES: THE COMIC VERSION

Supplementary multimedia prepared by lead author @ChiaWang8 to our recent @ScienceMagazine peer-reviewed paper

science.org/doi/10.1126/sc…

@kprather88 @linseymarr @zeynep @Lakdawala_Lab @zeynep
2/ The cast of characters: aerosols & droplets
3/ So what are aerosols?
4/ How can aerosols infect through airborne transmission? (by inhalation)
5/ What is the main difference between aerosols and droplets?
6/ How long can virus-containing aerosols linger in the air?
7/ Virus-containing aerosols are impacted by airflow and ventilation
8/ Racing with time: how long do infectious viruses survive in aerosols?
9/ Filters work well to remove infectious aerosols from the air (commercial HEPA or cheaper fan + filter like Corsi-Rosenthal box):
10/ Solar radiation and artificial UV light disable aerosols by damaging their genetic material. (But ventilation and/or filters are preferable to artificial UV whenever possible)
11/ Virus-laden aerosols can enter and deposit in the bronchiolar and alveolar regions of the lungs (also in the nose and upper respiratory tract):
12/ ACE2 is the cell entry receptor that binds and guides SARS-CoV-2 to invade cells
13/ Crowding indoors is a key element for superspreading events
14/ Why did so many people get infected despite mask wearing? (not wearing it tight to the face, or low quality filter)
15/ Surface disinfection CANNOT block airborne transmission (and is a waste of time and money):
16/ Plexiglas barriers may trap higher concentrations of aerosols! (and INCREASE, rather than decrease, transmission of the virus)
17/ How to stop airborne transmission?
- Keep distance (helps but not enough by itself)
- Ventilation, filtration (+UV in some cases)
- Masks w/ attention to fit to the face
- Avoid indoor crowding
18/ More information:

- Our scientists'FAQs: bit.ly/FAQ-A
- @ScienceMagazine review: science.org/doi/10.1126/sc…
- @TheLancet paper: thelancet.com/article/S0140-…
- @ScienceMagazine paradigm shift paper: science.org/doi/full/10.11…
- Transmission estimator: bit.ly/c-est
19/ There are many requests to translate to other languages. So far they are only in English, but I am inquiring if we can make the editable files available, will post here if so.
20/ If you want to download all the comic images at once, they are available in this folder:

drive.google.com/drive/u/0/fold…
21/ And for people more inclined to learn about the details, check out the literature references etc., this thread explains the @ScienceMagazine paper in more detail:

22/ A powerpoint version can be downloaded from this folder from @chiawang (it is the file that ends in "pptx"):

drive.google.com/drive/folders/…
23/ TRANSLATIONS: if interested in translating the comics, pls complete agreement in folder below, & send it to @ChiaWang8 at chiawang@mail.nsysu.edu.tw:

Translation to Indonesian, Thai, Dutch, and Sinhala is already underway. Help for others needed

drive.google.com/drive/folders/…

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More from @jljcolorado

May 19
1/ Las enfermedades pueden propagarse entre viviendas a través de los sistemas de ventilación compartidos EN ESPANA, según un estudio estadounidense

La nvestigacion analizó un brote de COVID-19 ocurrido en un edificio residencial de Santander al empezar la pandemia
2/ El articulo de la vanguardia q lo cuenta:



Investigacion de @ShellyMBoulder @D_Higuera_Ing et allavanguardia.com/magazine/biene…
@ShellyMBoulder @D_Higuera_Ing 3/ @ShellyMBoulder lidero la publicacion de nuestro estudio sobre la superpropagacion de COVID-19 en el coro de EEUU, que demostraba la transmision por el aire

doi.org/10.1111/ina.12…
Read 9 tweets
May 13
1) Something very clear from this Hantavirus outbreak is that @WHO is still quite confused about airborne transmission

Still confuse "close contact" (a setting) with a mechanism of transmission

Do not understand that ease of transmission in close proximity ==> likely airborne
2) Several colleagues have published this note in @bmj_latest summarizing this problem with @WHO:

bmj.com/content/393/bm…
@bmj_latest @WHO 3) I spent a couple of years of my life trying to make progress on this issue. This is how me and many colleagues felt during the pandemic.

Frustrating that @WHO is still very confused

Read 5 tweets
May 8
(1) Veo el lio que se ha montado con el hantavirus en el crucero y queria decir algunas cosas. La mas importante:

**Esto NO va a ser una pandemia**

Estoy de acuerdo con @mvankerkhove e incluso con Fernando Simon. Y nadie me puede acusar de estar siempre de acuerdo con ellos
(2) ¿Por que no vamos a tener una pandemia de hantavirus?

Porque es un virus q se conoce. La variante de los andes se puede transmitir de persona a persona. Casi seguro q se transmite por el aire, por aerosoles.

Pero con dificultad. NO es un virus muy contagioso.
(3) El hantavirus es menos contagioso que la tuberculosis pulmonar, que la causa una bacteria por transmision por el aire exclusivamente. Y que anda suelta por ahi, pero no causa una pandemia rapida como el SARS-CoV-2.
Read 19 tweets
May 26, 2024
1/ Survey of CO2 indoors during trip

CO2 (above ~400 ppm outdoors) indicates the amount of exhaled air (& virus) trapped in a space

Also per recent scientific results by @ukhadds, CO2 helps SARS-CoV stay infectious in air much longer

@united flight boarding, pretty terrible! Image
2/ This is the trip so far:

-Low outdoors
-Pretty high ~2000 in @RideRTD bus to airport
- ok ~800 at @DENAirport, except restroom ~1500. Not sure why restrooms at this airport are so often poorly ventilated
- Then boarding on @united, ventilation OFF, so huge increase till ON Image
3/ For details of the recent results on how and why CO2 makes SARS-CoV-2 stay infectious much longer in the air, see this recent thread by @ukhadds

Read 9 tweets
May 8, 2024
1/ "After four years of fighting about it, @WHO has finally proclaimed that viruses, including the SARS-CoV-2 virus that causes COVID, can be spread through the air"



By @maggiemfoxscientificamerican.com/article/a-figh…
2/ "It took four years to get here because some leaders in public health, medicine and science clung too tightly to precision and semantics"

"One particular moment of shame came on March 28, 2020, when WHO tweeted: “FACT: #COVID19 is NOT airborne.”

3/ "Words matter. When people heard that COVID might spread on surfaces, they wasted time wiping down groceries. People who misunderstood airborne spread needlessly wore masks on outdoor walks and veered off sidewalks to avoid their neighbors."
Read 7 tweets
Apr 18, 2024
1/ @WHO has published a report on updated terminology for disease transmission

I've seen some debate about it. My take:

- Terminology itself is ok. Big progress
- But no recommendations of how to protect!

Report:

Press release: who.int/publications/m…
who.int/news/item/18-0…
2/ The report was likely the result of intense pressure on @WHO during the pandemic:

- They denied that #COVIDIsAirborne on March 2020
- They finally accepted it 2 years later

nature.com/articles/d4158…
@WHO 3/ To their credit, @WHO did invite some of their critics to be part of the committee.

What was the terminology before. In medical circles:

- droplet transmission: if it happened in close proximity, or if particles were > 5 microns

- airborne transmission: if it happened far
Read 34 tweets

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