Published today in @TheLancet after peer review – our randomised controlled trial of a policy of daily lateral flow device testing vs quarantine for Covid-19 contacts in secondary schools and colleges. (1/8)…
18 months in, this is the first clinical trial anywhere examining interventions to manage Covid-19 in an educational setting. Young people have borne an enormous impact of pandemic controls. We need high quality evidence to safely reduce this impact. (2/8)
We found a daily contact testing did not significantly increase transmission (ie non inferior to unsupervised quarantine) via case rates throughout participating schools and colleges (intention-to-treat adjusted incidence rate ratio 0·96 [95% CI 0·75–1·22]; p=0·72)(3/8)
Not everyone took up an offer of daily testing, but taking into account results with high participation (CACE analysis), daily testing did not result in significantly more transmission (aIRR 0·86 [0·55–1·34]) (4/8)
Attendance in school was higher when daily contact testing was offered, but attendance was very variable, so we have uncertainty about that result and it was not statistically significant (aIRR 0·80 [95% CI 0·54–1·19]) (5/8)
Most notably, when we test asymptomatic contacts by PCR, 2 and 7 days after contact, only 1 of 67 contacts tests positive (1.5% and 1.6% in each group). School contacts rarely resulted in transmission. (6/8)
This study was conducted during a period where Delta was the dominant variant, but low-moderate incidence (19/4/21-27/6/21). Other mitigations (bubbles, distancing) were policy throughout, though masks were not mandatory after 17/5/21. (7/8)
We are so grateful to the schools and colleges who took part in this study. I hope many more follow to offer high quality, real world evidence to shape Covid-19 control policy. (8/8)

• • •

Missing some Tweet in this thread? You can try to force a refresh

Keep Current with Bernadette Young

Bernadette Young Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!


Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!