2/ There is good evidence to back additional doses of COVID vaccine for:
- HIGHLY immunocompromised
- Elderly
AND
- Nursing home residents
- Single-dose J&J recipients
BUT NOT for the general public at this time.
3/ We need to be thinking about the endgame, otherwise, we could find ourselves in a situation like Israel, chasing our tail with booster after booster:
4/ Yes, the Pfizer and Moderna vaccine regimens will likely end up being 3-dose vaccines, but there's no urgency to give 3rd doses to the general public now: nytimes.com/2021/08/09/opi…
with Drs. @CarlosdelRio7 & John Moore
5/ Because of how our immune system works and how injectable vaccines work, we won't be able to eliminate all SARS-CoV-2 breakthrough infections indefinitely with our current vaccines: theatlantic.com/ideas/archive/…
6/ We need to figure out the endgame & strategy that doesn't involve boosters every 6 months: theatlantic.com/ideas/archive/…
We need to use ALL the tools in our toolbox, not just vaccines.
7/ What are some of those other tools?
- Masks (at least for now)
- Upgrading building ventilation & air filtration (will protect us against other infectious diseases, too)
- Cheap, rapid testing
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1/ The decision to not get vaccinated, from the perspective of the unvaccinated
by @davidlazer & colleagues osf.io/fazup/
Life constraints
Perception of benefit
Perception of risk
Uncertainty regarding the risks of vaxx
Lack of trust in institutions
Fear of needles
2/ About 2/3 of respondents had already gotten at least 1 dose of vaccine.
15% willing to get vaccinated.
But 18% won't get vaccinated.
3/ Among those not yet vaccinated, here are their reasons for not getting vaccinated:
#1, #2 They are worried about the risks of vaccination.
#3 Lack of trust in institutions (eg gov't, healthcare)
#4 Don't see much of an upside (ie don't think they're at risk for COVID)
1/ @FDA’s are skeptical about the need for additional doses of COVID vaccine for the general public.
"data indicate that currently US-licensed or authorized COVID vaccines still afford protection against severe COVID disease & death in the United States"
There is good evidence to back additional doses of COVID vaccine for:
- HIGHLY immunocompromised
- Elderly
AND
- Nursing home residents
- Single-dose J&J recipients
BUT NOT for the general public at this time.
3/ We need to be thinking about the endgame, otherwise, we could find ourselves in a situation like Israel, chasing our tail with booster after booster:
1/ Agree with @EricTopol. There is good evidence to back additional doses of COVID vaccine for:
- HIGHLY immunocompromised
- Elderly
AND
- Nursing home residents
- Single-dose J&J recipients
2/ We need to be thinking about the endgame, otherwise, we could find ourselves in a situation like Israel, chasing our tail with booster after booster:
3/ Yes, the Pfizer and Moderna vaccine regimens will likely end up being 3-dose vaccines, but there's no urgency to give 3rd doses to the general public now: nytimes.com/2021/08/09/opi…
with Drs. @CarlosdelRio7 & John Moore