Lazarus Long Profile picture
Sep 20, 2021 12 tweets 6 min read Read on X
Here's a true CoVid story from the Chicoutimi Hospital in Quebec, Canada. From catastrophe to redemption.

Huge outbreak of 400 employees over 2.5 months, directly linked to nosocomial infections. 70 HAI patients.
To be frank, at first the employees were blamed.

Because of overtime due to CoVid - but the employees were blamed.

lequotidien.com/actualites/dur…

Was that the end of the story?
No. The workers did not want to catch CoVid. They were careful.

See the quote below from Anne who caught CoVid below.

And the outbreak continued, until someone decided to test the ventilation.
Right now, you just raised an eyebrow.

"Why test the ventilation? It's not airborne!"

But, as you can see above, Anne was wearing her droplet protection.

So, here were the ventilation results as measured in CO2 (a decent aerosol stand-in).

Up to 1611 ppm. In a hospital!
So, what did they do?

Spent $200,000 to improve the ventilation (bring in exterior air) and bring in negative pressure rooms.
The ventilation improved, as expected. But it wasn't quite enough.

Why? Ventilation/ filtration solve far-field aerosols, but cannot act quick enough to remediate aerosols that are up close (near-field aerosols).

Those can only be remediated by airborne PPE.
In February, N95's were mandated.

ici.radio-canada.ca/premiere/emiss…
N95's are great - but they can be expensive if replacing them all the time, right?

N100 Elastomeric respirators, though - a little more expensive up front - but within a few days much, much cheaper.

Have these been deployed anywhere? Yes- at the Alleghany Health Network.
13 hospitals, 250 locations, 21,000+ employees.

Here is Dr. Chalikondra, CMO of AHN (ahn.org/about/leadersh…), talking about that roll-out:


Or here is a study that was done on that roll-out:
journalacs.org/article/S1072-…
Here's a cost-save calculator from MSA for elastomeric respirators over N95's:
webapps.msasafety.com/apr-calculator/

But besides the cost-save that will make you the hero of your administration?

You will be the hero to the HCW's under your charge. Why?
After the AHN roll-out, guess how many wanted to go back to N95's? 0.

facs.org/media/press-re…

N100's medical grade silicone is much more comfortable than scratchy N95 material.

And safer since they protect against 99.97% of particles vs. 95%.

cdc.gov/niosh/npptl/to…
What about the patients? Like anything new - it's just a matter of education.



My DM's are open for any questions that you might have - not just HCW's! Regular people wear N100 elastomeric respirators, too:

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More from @LazarusLong13

Dec 21
Oh, we are cooked. Just cooked.

"Brain Mitochondrial dysfunction, known for ~20 years is finally recognized as a central upstream driver of Alzheimer’s disease (AD), not just a downstream effect."

And SARS2's targeting of mitochondria is well-known.

Even in the brain.
/1 We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease. Our work, combining multiple experimental and analytical methods, demonstrates the brain-wide impact of severe acute/subacute COVID-19, involving both cortical and subcortical regions, shedding light on potential therapeutic targets within pat...
@LauraMiers, in case you don't have it.

nature.com/articles/s4358…
@LauraMiers This is yet another reason why I N95.

Read 6 tweets
Dec 17
@neiljshaw - — a few tips on your excellent article from a clean air advocate

"Consider Wearing a Mask" ?

No, "It is incredibly important to wear a well-fitting mask such as a N95, KN95, or KF94, for the best protection."

You two are doing Image
public health with this article.

Public health is best done with simple clear instructions.

No:
"These masks act as a barrier, reducing the spread of respiratory droplets when people talk, sneeze or cough."

Yes:
"These masks act as a HEPA air cleaner for the face,
cleaning the air of respiratory aerosols when people breathe, talk, sneeze or cough."

The barrier carries the idea of an immovable wall. Unable to be penetrated by things like oxygen and CO2 - which feeds antimaskers.

As an who debunks antimaskers, it is
Read 9 tweets
Dec 11
As an anonymous clean air advocate, I've put a bit of thought into how to present, well, my expertise.

If someone were to say, "How do I know you know what you are talking about? Are you a doctor, or a virologist?"

To which, I would say...."No, but that's a good thing.
/1
I have focused on aerosol and masking science. Because it is those fields that give us the most information on how airborne particles, aerosols, get from Person A to Person B.

My expertise is derived from the great studies of Dr. Lindsay Marr, MacArthur recipient. Dr. Prather,
double National Academy member, Dr Milton, inventor of the Gesundheit, aerosol scientist and medical doctor; Dr Coleman whose group found that duckbill N95s captured 98% of emitted respiratory aerosols, and more excellent individual aerosol scientists.
Read 17 tweets
Nov 22
I am not a fan of nasal sprays to stop The 'Vid, but I respect you having it as a layer in the Swiss cheese package.

But, some people have said they got bloody noses.

While at the ER yesterday, I picked up a pretty good at home technique. Let our $1,000 lay-out
Image
save you money.

Use tongue depressors to make a nose pinch clamp.

Leave it on for 30 minutes. Still a problem? Two sprays of Afrin, and re-apply nose pinch clamp. Wait 30 minutes.

Still a problem? Cotton balls sprayed with Afrin, clamp, 30 minutes

aliem.com/trick-of-trade…Image
Image
Image
Afrin- in generic form is $3.32 at Walmart.

Also, put a ice compress at the back of the neck, while doing the above.

"Cooling the nape of the neck is said to induce reflex constriction of the mucosal vessels of the nose"

✅ I agree with the authors.

pubmed.ncbi.nlm.nih.gov/1568881/Image
Image
Read 6 tweets
Nov 13
A study demonstrated 100% PERFECT protection against SARS2 w/ readily available KF94s

✅ 181 HCWs
✅ 1 got SARS2 antibodies, but an epi investigation -> the infection happened elsewhere.
😡 The final checkpoint was March 2021. N95s only became freely available 1 month later
/1 FDA: N95 masks, now plentiful, should no longer be reused  By MARTHA MENDOZA and JULIET LINDERMAN  (Associated Press)  April 23, 2021 12:44 p.m.  Medical providers may soon return to using one medical N95 mask per patient, a practice that was suspended during the pandemic due to deadly supply shortages
What is described in the tweets
in the USA.

Korean study:
jkms.org/DOIx.php?id=10…

This is in comparison to a Swiss study during the same rough time-frame. A study which did NOT show the same excellent results, but dismal results. Why?

The Swiss had the same sort of fit testing,

pubmed.ncbi.nlm.nih.gov/35123572/ Results: We enrolled 3259 participants from nine healthcare institutions, whereof 716 (22%) preferentially used FFP2. Among these, 81/716 (11%) reported a SARS-CoV-2-positive swab, compared to 352/2543 (14%) surgical mask users; seroconversion was documented in 85/656 (13%) FFP2 and 426/2255 (19%) surgical mask users. Adjusted for baseline characteristics, COVID-19 exposure, and risk behaviour, FFP2 use was non-significantly associated with decreased risk for SARS-CoV-2-positive swab (adjusted hazard ratio [aHR] 0.8, 95% CI 0.6-1.0) and seroconversion (adjusted odds ratio [aOR] 0.7, 95% CI ...
PPE monitoring.

What was the big difference?

Are N95s/FFP2s inferior to KF94s?

No, it was supply - and other reasons.
Read 10 tweets
Nov 5
@tomhanks has just been savaged by people screaming masks don't work.

All hospitals have fiduciary responsibilities to not waste money.

Here is a light sampling of hospitals mandating masks because they work.

Proving that not only do masks work, but mask mandates work.

Thread
Health PEI
Start/End: October 14, 2025 , How many hospitals: 7, employee count: 4,967,

Public hospital,

City: Various (e.g., Charlottetown, Summerside), Province: Prince Edward Island, Country: Canada, full url: princeedwardisland.ca/en/news/health…
Horizon Health Network
Start/End: September 3, 2025 How many hospitals: 12, employee count: 15,000, public or private:

Public hospital.

City: Various (e.g., Saint John, Fredericton),
Province: New Brunswick,
Country: Canada horizonnb.ca/coronavirus-co…
Read 32 tweets

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