Lazarus Long Profile picture
Clean Air Advocate. I know how you can avoid those infections - and what they do to you, if you do get infected. #PZC. 19-2.
20 subscribers
Dec 21 6 tweets 3 min read
Oh, we are cooked. Just cooked.

"Brain Mitochondrial dysfunction, known for ~20 years is finally recognized as a central upstream driver of Alzheimer’s disease (AD), not just a downstream effect."

And SARS2's targeting of mitochondria is well-known.

Even in the brain.
/1 We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease. Our work, combining multiple experimental and analytical methods, demonstrates the brain-wide impact of severe acute/subacute COVID-19, involving both cortical and subcortical regions, shedding light on potential therapeutic targets within pat... @LauraMiers, in case you don't have it.

nature.com/articles/s4358…
Dec 17 9 tweets 3 min read
@neiljshaw - — a few tips on your excellent article from a clean air advocate

"Consider Wearing a Mask" ?

No, "It is incredibly important to wear a well-fitting mask such as a N95, KN95, or KF94, for the best protection."

You two are doing Image public health with this article.

Public health is best done with simple clear instructions.

No:
"These masks act as a barrier, reducing the spread of respiratory droplets when people talk, sneeze or cough."

Yes:
"These masks act as a HEPA air cleaner for the face,
Dec 11 17 tweets 3 min read
As an anonymous clean air advocate, I've put a bit of thought into how to present, well, my expertise.

If someone were to say, "How do I know you know what you are talking about? Are you a doctor, or a virologist?"

To which, I would say...."No, but that's a good thing.
/1
I have focused on aerosol and masking science. Because it is those fields that give us the most information on how airborne particles, aerosols, get from Person A to Person B.

My expertise is derived from the great studies of Dr. Lindsay Marr, MacArthur recipient. Dr. Prather,
Nov 22 6 tweets 4 min read
I am not a fan of nasal sprays to stop The 'Vid, but I respect you having it as a layer in the Swiss cheese package.

But, some people have said they got bloody noses.

While at the ER yesterday, I picked up a pretty good at home technique. Let our $1,000 lay-out
Image
save you money.

Use tongue depressors to make a nose pinch clamp.

Leave it on for 30 minutes. Still a problem? Two sprays of Afrin, and re-apply nose pinch clamp. Wait 30 minutes.

Still a problem? Cotton balls sprayed with Afrin, clamp, 30 minutes

aliem.com/trick-of-trade…Image
Image
Image
Nov 13 10 tweets 5 min read
A study demonstrated 100% PERFECT protection against SARS2 w/ readily available KF94s

✅ 181 HCWs
✅ 1 got SARS2 antibodies, but an epi investigation -> the infection happened elsewhere.
😡 The final checkpoint was March 2021. N95s only became freely available 1 month later
/1 FDA: N95 masks, now plentiful, should no longer be reused  By MARTHA MENDOZA and JULIET LINDERMAN  (Associated Press)  April 23, 2021 12:44 p.m.  Medical providers may soon return to using one medical N95 mask per patient, a practice that was suspended during the pandemic due to deadly supply shortages
What is described in the tweets
in the USA.

Korean study:
jkms.org/DOIx.php?id=10…

This is in comparison to a Swiss study during the same rough time-frame. A study which did NOT show the same excellent results, but dismal results. Why?

The Swiss had the same sort of fit testing,

pubmed.ncbi.nlm.nih.gov/35123572/ Results: We enrolled 3259 participants from nine healthcare institutions, whereof 716 (22%) preferentially used FFP2. Among these, 81/716 (11%) reported a SARS-CoV-2-positive swab, compared to 352/2543 (14%) surgical mask users; seroconversion was documented in 85/656 (13%) FFP2 and 426/2255 (19%) surgical mask users. Adjusted for baseline characteristics, COVID-19 exposure, and risk behaviour, FFP2 use was non-significantly associated with decreased risk for SARS-CoV-2-positive swab (adjusted hazard ratio [aHR] 0.8, 95% CI 0.6-1.0) and seroconversion (adjusted odds ratio [aOR] 0.7, 95% CI ...
Nov 5 32 tweets 11 min read
@tomhanks has just been savaged by people screaming masks don't work.

All hospitals have fiduciary responsibilities to not waste money.

Here is a light sampling of hospitals mandating masks because they work.

Proving that not only do masks work, but mask mandates work.

Thread Health PEI
Start/End: October 14, 2025 , How many hospitals: 7, employee count: 4,967,

Public hospital,

City: Various (e.g., Charlottetown, Summerside), Province: Prince Edward Island, Country: Canada, full url: princeedwardisland.ca/en/news/health…
Nov 2 39 tweets 13 min read
Thread of debunking the myth that "babies should not be masked."

A baby uninfected is better than a baby infected.

If you oppose masking babies, you are immediately for infecting babies.

Let's get to it. A most excellent instruction page on how to mask babies.  Suck it antimaskers. This solves an equity problem.

Not everyone has the money or technical skill to build a baby buggy PAPR.

Just like not everyone has the money to buy an adult PAPR.

Are you for people on SNAP being able to protect their babies? Or not?

Oct 22 19 tweets 8 min read
If you are Covid Aware you have probably been avoiding the dentist. Well, the dental studies have come to you.

This edition? #CovidAwareSoReducingDentalVisits - Water flossing (WF) edition.

Or, as I like to think of it, the Gum Salon.

Thread. Flossing is necessary for those super tight contact points as you see in the above thread, and is great to remove plaque down 1 mm deep in the gum line (gently).

InterDental Brushes are fantastic and go down 2-3 mm into the gum line to remove plaque.

Oct 9 27 tweets 9 min read
I remember why I got going on this run of dental care threads.

I got a root canal, and then a cleaning. The hygienist told me that masks cause dental problems. I didn't say anything, but that's complete horse...puckies.

#CovidAwareSoReducing - Plaque/ Toothbrush edition. It upset me, to be frank, and when I get fired up, I act. Since she is very nice, albeit uneducated on masking, I let it go - with her.

But I decided to figure out what I was doing wrong.
And it was everything.

I was brushing and flossing losing 1-2 microns of enamel
Oct 8 25 tweets 10 min read
#CovidAwareSoReducingDentalVisits - less mouth open = less 'vid risk.

I am a GREAT flosser. My family thought we had genetic gum disease.

Below we can see rubber stick on the left, floss on the right, and a InterDental Brush (IDB) in the middle.

See the problem?
/1 Image A couple more example pics on why I am sick to my stomach thinking of all that money wasted.

We THOUGHT we had great dentists. Not a single one mentioned IDBs, and how the bristles allow all interdental spaces to be reached.

And it gets better!

/2 Image
Image
Oct 7 24 tweets 9 min read
Covid Aware Teeth

The Calcium Lactate Rinse. Cheap, super easy to do - and it really enhances your fluoride uptake to re-enamel your enamel.

It's just not very well known, despite being very well supported within studies - and very cheap.

Mix 1/8 tsp with 1 oz water. Shake thoroughly, till the granules disappear. Takes a few or 20 shakes, then just wait. Rinse for 1 minute. Spit out.

Immediately brush with fluoride or fluoride rinse.

There might be a better powder
amazon.com/dp/B0DHXX9LYC?…

1/8 tsp
amazon.com/dp/B0D5LH3K1H?…

pmc.ncbi.nlm.nih.gov/articles/PMC38… Image
Sep 18 10 tweets 4 min read
.On the one hand, we have study after study showing 36% or so rate of LongCovid.

On the other, we have the WHO saying the rate of LongCovid is only 6%.

I got curious. What drugs are the WHO smoking - and can I get some?

🧵. Image My 36% comes from the latest massive meta:
eatg.org/hiv-news/more-…

But what about that 6%?

Turns out it's this old chestnut from 2022.

And there are such major players on it...so many I can't even screenshot them all.

But I fear no title - and neither

jamanetwork.com/journals/jama/… Image
Sep 7 8 tweets 4 min read
COVID is as transmissible as measles?!

"BUT, BUT, measles can infect up to 90% of people they are in contact with!"

So can COVID.

Time to wake up. The lecturer tried to promote sales of a flax oil product, and many elderly people were lured to attend by the promise of free eggs, Xinhua News Agency reported.  He gave three lectures on Jan 10 and 11 in a Tonghua classroom while not wearing a mask, with each lecture lasting about 2.5 hours. A total of 97 people, most of them retirees, attended the lectures in a classroom whose doors and windows were closed, the China CDC report said. The lecturer went to a pharmacy at noon on Jan 10 due to muscle pain and other symptoms, indicating he was likely at an early stage of the disease then, it ... weekly.chinacdc.cn/en/article/doi…

govt.chinadaily.com.cn/s/202102/20/WS… Image
Sep 6 8 tweets 4 min read
Remember THAT scene from Outbreak with Dustin Hoffman - "It's Airborne." ?

SARS-COV-2 is airborne via HVAC. Just like TB is - but it is way more contagious.

Still no panic, right? We know how to be safe.

Motel 6, or AirBNB - no shared HVAC, is best.

But HOW do we know?

🧵 A recent study in South Africa used Syrian Hamsters to duplicate the study that finally convinced everyone that TB was airborne.

The TB study is interesting because the military vets in VA hospitals were getting infected disproportionately.

So, they used HVAC ducting to In 1956, tuberculosis was a major global killer, and it disproportionately affected military veterans hospitalized in the Veterans Administration hospital system. Then, as now with COVID-19, epidemiologists held that tuberculosis and other respiratory diseases were spread by large infected droplets through person-to-person contact or contaminated surfaces. But Richard L. Riley, an expert on lung physiology at the then Johns Hopkins School of Hygiene and Public Health, and his mentor, William F. Wells, had identified another possible mode of transmission.
Sep 1 35 tweets 10 min read
Plaque, Stephan's Curve (Imperative) mixed with breakfasts that you can brush immediately after.

It's actually best if you brush immediately up on waking up. This gets the overnight plaque.

It starts forming 4-6 hours after you sleep - your saliva is 20 millititers/hr Dental Plaque on the bristles of a used toothbrush.  Yep, that came out of your mouth. - during the day. At night? Just 3-6 ml.

Saliva washes away the bacteria, it contains bicarbonate, phosphate, and protein buffers that neutralize the acids being pooped out by the bacteria.

It also has the below ingredients. Who knew saliva was so cool?!

Or plaque? Antimicrobial Components  Lysozyme: breaks down bacterial cell walls.  Lactoferrin: binds iron, starving bacteria.  Peroxidases: inhibit bacterial metabolism.  Immunoglobulin A (IgA): prevents bacterial adhesion to teeth.
Plauque forming bacteria.
Aug 29 15 tweets 6 min read
Kind of funny...I just realized that I can use my research skills and figure out how to have a better oral biome.

Ever heard of the Stephan Curve? Described in 1943, it describes the point at which the pH in your mouth goes down to the Danger Zone (hey Tom Cruise), and your ph 5.5 is the point at which Tom pHruise gets Dangerous.  Y'all be in the Danger Zone, yo! teeth start being demineralised.

Turns out that your saliva will start getting you back to the Safe Zone after about 30-40 minutes.

Unless you are like me.... Notice no teeth brushing there, brah?  Well, ya better be brushing 3 times per day.
Aug 27 24 tweets 9 min read
Ah, it's that time of year again. The pitter patter of children's feet. The laughter of high school students as they flirt with each other.

The coughs of their parents.

Is a Portable Air Cleaner (PAC) on a desk aimed at the wee ones' faces going to protect them? Spicoli from Fast Times at Ridgemont High with a Levoit Air Cleaner pointing at his face braced up with a weight.  In the middle of his pizza.  Not cool, man, not cool. TLDR? No. They need to be in a N95 or KF94 purchased from legit distributors, not from Amazon, and eat their food outdoors, spaced far enough away from their friends so as not get infected. Or use @sipmask and protein shakes at lunch in the cafetaria.

You need to teach them
Aug 23 7 tweets 2 min read
People often underestimate the power of having someone with the reputation of Wolfgang Leitner, weighing in.

This is truly a significant development.

Personally, I prefer to let the studies do their own talking, but Voice Of Authority bears considerable weight in the real world Just a few awards Image
Aug 22 18 tweets 7 min read
FACT: #COVID19 is NOT airborne.

Despite Tedros saying it was airborne on February 11th, 2020

thread. We know that #COVID19 is not airborne because the WHO told us so, again on March 28th, 2020.

who.int/docs/default-s…

x.com/WHO/status/124… FACT: #COVID19 is NOT airborne.   The #coronavirus is mainly transmitted through droplets generated when an infected person coughs, sneezes or speaks.  To protect yourself: -keep 1m distance from others -disinfect surfaces frequently -wash/rub your 👐 -avoid touching your 👀👃👄
Aug 21 15 tweets 5 min read
Calley is lying from the very first sentence. The media is not cheering for MAHA to fail. They are cheering for antivaxxers to fail.

We all want to see better food, less chemicals.

But we are not idiots.

The single largest gain in American life expectancy was between 1900 and 1940, primarily because of improved water & sewer sanitation. Adding 16 years of life expectancy.

And vaccines are a close second - adding 5-10 years a bit later - in the last half of the century.

If we get rid of vaccines? We lose 5 to 26 years, depending
Aug 19 18 tweets 7 min read
Microplastics.

In your testicles. Or your ovaries. Your brain and other organs.

But where do they come from? Are you eating, drinking, or breathing them in?

3 biggest fixes you can do? Get a water filter that handles PFAs - it will also do Image also handle microplastics easily. Next, rinse off your vegetable and fruit with that filtered water.

When driving around in your car? Have a little HEPA running. @cleanairstars is a great resource. @ThisHouseFresh has a handy RV HEPA review article.