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Lazarus Long Profile picture
@LazarusLong13
Sep 24, 2021 • 11 tweets • 5 min read • Read on X
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I'd like to invite you to go scilunking with me.

What is scilunking? It's spelunking within studies.

First cave we enter, Dr. Gurdasani's headlamp shows us that kids infect each other...and their parents.

This is a great thread! Read it, then come back for .... gold!
Her second tweet had this study. A genomic tracing study and confirmation of transmission within schools.

wwwnc.cdc.gov/eid/article/27…

But something in this cave caught the corner of my eye.

A furtive movement.

"most school-associated cases are acquired outside of school"
Hoeg.

A cold wind blows from the depths of the cave.

Dare we?

"Hey, I was promised GOLD, not HOEG!"

You are right, let's go deeper.
ncbi.nlm.nih.gov/pmc/articles/P…

Our headlamps have found gold! 37% less transmission in school!

Where will you spend yours?

Wait a second though. There's something off about this gold.

It's fool's gold.
✅ Kids are often asymptomatic.
⚠️Absence of child to staff transmission does not mean transmission in school is uncommon. We'll come back to this.
⚠️ Reference #5 says asymptomatic attack rate is only .7% within household, so we are to believe kids don't transmit.
So, we move sideways into that cave, and we see what that study says.

jamanetwork.com/journals/jaman…

It says asymptomatic index cases are .7%.

Which means the first person found to be infected was asymptomatic.

Does not state if child or adult.
Were children actually addressed?

Yes. Data was limited, but a study was found indicating relatively high transmission from kids!

The exact opposite of what Hoeg tried to fool us into believing!

And thus, we have our fool's gold.
Remember I promised to come back to child to adult transmission?

About that. Hoeg's study was in Wood County, Wisconsin, September-November 2020.

Guess what they had in school?

Teachers and students wearing masks.

In rural Wood County, did they have a mask mandate? Yes.
Technically.

The state was under a mask mandate.

But the sheriff said there would be no enforcement.

waow.com/2020/07/31/lis…

So, in all likelihood, there was much less mask wearing in the community than the 92-97% mask wearing in the school.
And for sure there was no cohorting, etc. in the community.

But all of those NPI's were in the school.
And this is the real gold from this scilunking expedition:

NPI's work.

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More from @LazarusLong13

Lazarus Long Profile picture
Nov 18
Fascinating educational article about vaccines and the immune system.

And this was an interesting bit -
Bacterial and viral infections predispose to other infections.

Get the flu? You are at greater risk for pneumococcal pneumonia.
/1 Bacterial and viral infections, on the other hand, often predispose children and adults to severe, invasive infections with other pathogens. For example, patients with pneumococcal pneumonia are more likely to have had a recent influenza infection than matched controls.62 Similarly, varicella infection increases susceptibility to group A-hemolytic streptococcal infections such as necrotizing fasciitis, toxic shock syndrome, and bacteremia.63
Those 👇 post influenza infection effects look familiar.

Where have I seen those types of symptoms before?

COV_D. Which we are getting every year, unlike the flu which is every 5-6 years.

Anywho.....

wellesu.com/10.1086/313772The theoretical bases for susceptibility to bacterial pneumonia following influenza infection are plentiful and include decreases in the function of polymorphonuclear leukocytes, macrophages, lymphocytes, and monocytes; increases in the adherence of bacteria to the respiratory epithelium; and decreased mucociliary clearance [14–19]. In studies of pneumococcal pneumonia in mice and squirrel monkeys, greater severity of disease and mortality resulted from infections due to pneumococcus and influenza virus together than from infections of either organism alone [20–21]. These animal studies sup...
Varicella (chickenpox)? Leads to Group A-hemolytic Streptococcal infection. Known affectionately as GAS, and exhibiting as
necrotizing fascitis.

researchgate.net/publication/12…VZV infection itself may cause a predisposing immune aberration or may allow invasion via another less apparent portal, such as lesions on the oral mucosa or the respiratory tract. In favor of an immune aberration is the fact that NF, the most severe manifestation of soft tissue infection, tended to occur more commonly in association with chickenpox than in nonchickenpox cases. Furthermore, Fujimara et al33 have presented evidence of a switch of the CD41 T cell profile in patients with varicella and underlying atopic dermatitis from a TH2 toaTH1 dominant type with a relative immunosuppressi...
Read 14 tweets
Lazarus Long Profile picture
Nov 16
I have my head so far up the governmental cow's butt on this one, I think I am uniquely qualified to answer on the difference between Biden and Trump on H5N1.

Ready for a🧵?
Biden's USDA is still denying airborne, and is still not telling the Spanish-speaking dairy workers that it is airborne. Or to wear an N95.

Biden's CDC is running Spanish ads on the radio and Facebook. Offering testing. Workers still not trusting the CDC.
Trump will get the CDC to continue to offer free testing clinics - and arrest the workers when they come in.

Nobody will want to milk or take care of the cows. They will continue to get sick, but really die without the intensive care they actually need with H5N1.
Read 15 tweets
Lazarus Long Profile picture
Nov 15
You go to the doctor to get better, not sicker.

There is a group called the HICPAC that tells the CDC what they should do regarding whether or not the guy with bright pink eyes in the bed next to you is wearing an N95 or not.

Whether your doctor comes back from Bermuda with
Covid - and either wears an N95 when he sees you or not.

Whether the hospital gives you attitude about your N95 - or joins you in wearing an N95.

They are going to vote today to say that Surgical Masks are Respiratory Protective Equipment - which is a lie. Per NIOSH/ OSHA.
What can you do?

Read this thread and then call the Inspector General’s office is very receptive. The direct phone number is 202-619-3148. Tell them the HICPAC did what is in that thread, and about them ignoring all airborne evidence.

Read 11 tweets
Lazarus Long Profile picture
Nov 14
The Canada BC teenager is in a hospital that barely uses surgical masks, under Bonnie Henry who screwed up SARS1, then C0V1D.

She thinks aerosols only come in cans.

⚠️ Trigger ⚠️

I am going to lay out the worst case for you. Going to get dark.
First, the subclade, or variant, that this poor kid has is D1.1.

It is not the dairy cow subclade - that is B3.13.

Good breakdown of what a clade is here:
cdc.gov/flu/about/viru…

D1 is lighting up the Pacific flyway.

33 outbreaks in 2.5 weeks.

x.com/0bFuSc8/status… Pacific flyway is basicallywedt of the western tip of Texas, Wyoming etc.
"Genotype D1.1 has:
• Eurasian HA, PB1, MP, NS – all ea3
• North American PB2 (am24), PA (am4), NP (am13), NA [am4(N1)]"

PB2 is not good.

Read 16 tweets
Lazarus Long Profile picture
Nov 13
Numerous people are pointing out that C0V1D brings with it "pink eye" - conjunctivitis.

It also brings with it some interesting comparisons to H5N1.

Some thoughts on both. If you are trying to minimize your exposure to airborne diseases, you will want to read this.

🧵 Mystery thread star. Next tweet for their name.
It was Dr Li Wenliang, an opthalmologist, who first publicly warned us all, may he rest in peace.

He was seeing ophthalmological problems, and that led him to alert us all.

bbc.com/news/world-asi…Picture of Dr Li in a hospital with Covid.
But no one thinks about the eyes getting infected with aerosols.

There is a reason for that - we are far more likely to breathe it in as we inhale 2,900 gallons or 11,000 liters of air.

C0V1D is very airborne (Ashish Jha called it purely airborne).

Read 11 tweets
Lazarus Long Profile picture
Nov 12
So, while I was reading up for the below thread, I came up across an interesting bit about H5N1 and eyes.

How ARE those 👇 eyes getting infected? Rubbing their eyes with dirty, dirty hands?

Thread. Dairy worker with bird flu never developed respiratory symptoms, only pinkeye The authors of a new report detailing the man's case suspect that he was infected by rubbing his eyes with a contaminated hand.
The CDC just did a serologically study that calls into question those dirty, dirty hands - if you even only half-carefully read it.

3 of the 8 showing antibodies had used eye protection. A little difficult to stick your fingers in your eyes with eye protection on. Among 115 persons, eight (7%; 95% CI = 3.6%–13.1%) had serologic evidence of recent infection with A(H5) virus; all reported milking cows or cleaning the milking parlor. Among persons with serologic evidence of infection, four recalled being ill around the time cows were ill; symptoms began before or within a few days of A(H5) virus detections among cows.
Cleaning the milking parlor was the only task significantly associated with a positive test result (p<0.001). None of the workers with serologic evidence of infection used respiratory protection; three used recommended eye protection. Among the eight workers with evidence of infection, only one reported close contact with cows known to be infected,§§§§ compared with 68 (64%) workers with negative test results. However, all worked on farms with herds that were reported to public health officials as being HPAI A(H5)–infected.
Only 1 of the 8 had close contact. So, that means either fomites or more than 6 feet away infection.

It also means no droplets.

But none of the 8 were wearing respiratory protections - so no protection from aerosols. Cleaning the milking parlor was the only task significantly associated with a positive test result (p<0.001). None of the workers with serologic evidence of infection used respiratory protection; three used recommended eye protection. Among the eight workers with evidence of infection, only one reported close contact with cows known to be infected,§§§§ compared with 68 (64%) workers with negative test results. However, all worked on farms with herds that were reported to public health officials as being HPAI A(H5)–infected.
Read 31 tweets

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