1/ What's the BIGGEST DOWNSIDE to giving ALMOST EVERYONE boosters?

REINFORCING MISPERCEPTIONS that:
- Vaccines are silver bullets
- Breakthrough infections mean vaccines are failing

Vaccines are necessary but not sufficient.
2/ Vaccines provide a relative risk reduction.

Your risk of a SARS-CoV-2 infection after vaccination remains proportional to the level of transmission in your community.

The best way to minimize your risk isn't boosters. It's to address transmission in your community.
3/ How do you reduce transmission in your community and thereby reduce your risk?
- Vaccinated the UNvaccinated
- Mask (at least for now)
- Indoor ventilation & air filtration (we don't do NEARLY enough of this)
- Test 2-3 times/week & isolate infectious persons
4/ Boosters are unlikely to provide more than a few month-long boost in antibody levels.

It's unclear they'll do anything for your long-term memory immune response.

We'll likely find ourselves right back to where we were pre-boost a few months later.

theatlantic.com/ideas/archive/…

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Keep Current with Céline Gounder, MD, ScM, FIDSA

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More from @celinegounder

24 Sep
1/ Overnight, @CDCDirector overrode the @CDCgov's ACIP recommendations on vaccinating workers in high-risk occupations.

politico.com/news/2021/09/2…

It's important that we be clear WHY.
2/ Are we giving boosters to people in high-risk occupations:
- To protect them because they're at high risk for severe disease?
OR
- For the safety of the workplace & to keep them on the job?
3/ There isn't good data to support giving boosters to people in high-risk occupations to protect THEM from severe disease.
Read 8 tweets
24 Sep
1/ @CDCgov guidance on who SHOULD get a booster 6+ months after *PFIZER*:
- 65+ & nursing home residents
- 50-64 with underlying medical conditions

Who MAY get a booster 6+ months after *PFIZER*:
- 18-49 with underlying medical conditions
- people in high-risk occupations
2/ What counts as an underlying medical condition?
Cancer
Cerebrovascular disease (stroke)
Cardiovascular disease (heart attack) & heart conditions
COPD (emphysema, chronic bronchitis)
Diabetes
Obesity (BMI 30+)
Current/recent pregnancy
Current/former smoker
Read 9 tweets
23 Sep
1/ Q&A with @NewYorker's Helen Rosner @hels
about what COVID booster shots can and can't do
newyorker.com/news/q-and-a/w…
- who might benefit from a 3rd shot
- how to prevent breakthrough infections
3/ How do vaccines work?
newyorker.com/news/q-and-a/w…
Read 12 tweets
23 Sep
1/ New research by the Institute for Research and Education on Human Rights @IREHR finds that Facebook has become an epicenter of COVID denial activism:

irehr.org/reports/facebo…
2/ Facebook COVID denial group membership:
- 1,732 groups
- 2,445,602 members
Read 4 tweets
23 Sep
1/ This year, please get your flu shot.

Even if you're one of those people who say you don't "do that," whatever that means.
Or one of those people who say you "never get the flu."

This year promises to be an especially bad flu season.

theatlantic.com/science/archiv…
Read 4 tweets
22 Sep
1/ How did Denmark get 95% of people 50+ fully vaccinated?

"citizens’ high and stable trust in their health authorities has been a crucial factor"
"lack of trust in authorities... is one of the primary reasons people refuse to get vaccinated"

washingtonpost.com/politics/2021/…
2/
"transparent communication about all features of vaccines—including the negative ones—is key to sustain trust, even if in the short run it reduces vaccine acceptance"
washingtonpost.com/politics/2021/…
3/
"trust between citizens and the authorities ideally runs both ways, as authorities need to trust that citizens can weather bad news and still make responsible decisions"
washingtonpost.com/politics/2021/…
Read 9 tweets

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