Figuring out what causes what is SO HARD

And especially if you have a psych background, you might think we *need* an experiment to understand causes

While I love experiments, here's a thread of resources on why they're neither necessary nor sufficient to determine causes 🧵
This paper led by @MP_Grosz is a great start! It persuaded me that merely adjusting our language (eg saying "age is positively associated with happiness" instead of "happiness increases with age") isn't enough

journals.sagepub.com/doi/full/10.11…
If our underlying research question is causal, we still need causal methods! But if they're not just experiments, what are the options?

Luckily for us @dingding_peng has a must-read primer on using causal methods with non-experimental data

journals.sagepub.com/doi/10.1177/25…
Reading this paper helped me understand experiments are incredibly useful, and they aren't a "get out of jail free card" for determining causes

She also covers the basics of using directed ayclic graphs (DAGs) for understanding causes, and I found her explanations super useful!
Taking causal inference seriously can also help us more effectively answer research questions we care about!
A big question in intervention science is how intervention effects might differ if they were administered in new populations

This framework led by @dominik_deffner helps us understand how we could do just that (plus lots of other stuff too!)
psyarxiv.com/fqukp
This paper also does a great (and unsettling!) job of discussing how even if your research questions seem more descriptive you still have to think about causal models

Have I mentioned science is hard??
There are other cool frameworks for understanding intervention effects in new contexts like this from @economeager (though I'll admit a lot of it is over my head as of right now!)

lse.ac.uk/economics/Asse…
Want a textbook length treatment?

I've learned a bunch about how to think about science along doing causal inference in complex circumstances from Statistical Rethinking by @rlmcelreath

Book ($): xcelab.net/rm/statistical…
Lectures (Free): youtube.com/playlist?list=…
If a textbook is too intimidating he has a series of blog posts that get at some of the book's core concepts:

elevanth.org/blog/2021/06/1…
If wading into this lit causes you to have a bit of an existential crisis about how we do research, you're not alone!

I really vibe with this thread by @ShirleyBWang that breaks down the need for more time and space for people to learn difficult methods
I'm super lucky/privileged to be in a position where I get to learn as much as I do, and most people don't get that chance

I hope this list of resources is at least a bit of help to people who are interested but didn't know where to start!
PS Diving into the causal inference lit has helped me realize a lot of the questions I care most about are prediction-focused

If you're interested in a primer on prediction-focused approaches, check out this paper from @talyarkoni
ncbi.nlm.nih.gov/pmc/articles/P…

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More from @mcmullarkey

1 Oct
If you ever want to sound like an expert without paying attention, you only need two words in response to any question

"It depends"

A thread on why we should retire that two word answer 🧵
When people say "it depends" they often mean the effect of one variable depends on the level of at least one other variable

For example:
You: Does this program improve depression?
Me, Fancy Expert: Well, it depends, probably on how depressed people were before the program
Understandably you'll want some evidence for my "it depends"

Luckily my underpaid RA has already fired up an ANOVA or regression, and *I* found that how depressed folks were before the program moderated the effect of the program

"It depends" wins again?

Nope, so many problems
Read 23 tweets
29 Sep
If we prioritized improving patients' and trainees' lives clinical psych's structures would look entirely different

A part touched on but (understandably!) not emphasized in this piece: There's vanishingly little evidence our training improves clinical outcomes for patients
🧵
Multiple studies with thousands of patients (though only 23-39 supervisors each!) show that supervisors share less than 1% of the variance in patient outcome

And that's just correlation, the causal estimate could be much smaller

tandfonline.com/doi/full/10.10…

journals.sagepub.com/doi/full/10.11…
There's evidence supervisors and trainees care more about a supervisors' "relational characteristics" than their "transmission of clinical know how"

It's ok to want to spend time with people we like, and there's no guarantee that will help patients

ncbi.nlm.nih.gov/pmc/articles/P…
Read 14 tweets
27 Sep
Where should folks turn if they want mental health support for depression *right now* and aren't in crisis?

Traditional talk therapy often has long waitlists

The therapy apps you've heard about promising quick access to treatment have lots of problems

What I recommend 🧵
Adults Part I

Program: Deprexis
Content: 10 self-guided, internet-based modules (most grounded in evidence-based approaches)
Cost: ~1-2 sessions of therapy ($280)
Evidence: Solid meta-analytic evidence across >10 RCTs journals.plos.org/plosone/articl…
Link: orexo-store-2.mybigcommerce.com
Adults Part II

Program: MoodGYM
Content: 5 self-guided, internet-based modules (all grounded in CBT-based approaches)
Cost: <1 session of therapy ($27)
Evidence: Somewhat shaky meta-analytic evidence across >10 RCTs researchgate.net/profile/Conal-…
Link: moodgym.com.au
Read 8 tweets
19 May
Still responding to folks re: my transition to data science post! I'll get to everyone, promise!

Given the interest I thought people might want to know the (almost all free/low cost!) resources I used to train myself for a data science role

A (hopefully helpful) 🧵
R, Part I

My first real #rstats learning experience was using swirl. I loved that I could use it inside of R (rather than having to go back and forth between the resource and the RStudio console)

swirlstats.com/students.html
R, Part II

A cliche rec, but it's cliche for a reason. R for Data Science by @hadleywickham & @StatGarrett transitioned me from "kind of messing around" to "wow, I did that cool thing" in R. It's absolutely a steal that it's available for free

r4ds.had.co.nz
Read 14 tweets
28 Feb
I just found out a paper we first submitted ~3 years ago was accepted! We used an N > 1,000 sample, open data/code, and robust methods

I'm proud of this paper, and it also helped radicalize me against a lot of the stories we tell ourselves about peer review

A 🧵
The many reviews we received were almost uniformly hostile, confused, non-constructive, or some combination
The paper definitely got better throughout the process, and that had ~0 to do with the reviews

Real reason #1: A wonderful, ongoing collaboration with a stellar biostatistician/many other great collaborators

Real reason #2: I got better at coding/new tools became available
Read 22 tweets
5 Sep 19
Trying to balance:
- Having genuine empathy for people who are staring down the barrel of their life's work not replicating
- Not reinforcing power structures and practices that led to a world where those barrels are all too common
Hearing @minzlicht talk about this on the "Replication Crisis Gets Personal" @fourbeerspod episode brought home to me how lucky I am to be early in my career now as opposed to 20 or even 10 years ago
But his example* reminds me people in power have a choice when confronted with a much messier literature than initially described

They can double down, or they can engage meaningfully with a more complicated world

*And many others, my mentions aren't ever comprehensive!
Read 12 tweets

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