1/ Black pastors are preaching God's word & public health.
They're working to save the souls & lives of their flock.

nytimes.com/2021/10/09/nyr… Image
2/ Only 55% of Black New Yorkers have received at least one vaccine dose.

Black & Brown people have good reason to doubt the government & health system:
justhumanproductions.org/podcasts/s1e68…
3/ Vaccination rates are even lower among young Black New Yorkers:
Only 48% between 18 and 44 have gotten at least one dose of COVID vaccine

And only 30% of Black Americans under 40 attend a Black church.
4/ This means that older Black New Yorkers need to reach out to younger Black New Yorkers...

in addition to NYC Dept of Health @nycHealthy outreach: Image

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Keep Current with Céline Gounder, MD, ScM, FIDSA

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More from @celinegounder

11 Oct
1/ Study of ~9M people in NYS
medrxiv.org/content/10.110…

May: NYS adopted CDC guidance for fully-vaxxed
June: end of NYS’ state of emergency (⬇️mask-wearing, distancing etc)
July: CDC recommended mask usage for fully-vaxxed based on transmission levels
July: Delta became dominant
2/ COVID vaccine effectiveness vs HOSPITALIZATION:

Among 18-49 year-olds:

Pfizer/Moderna: >90%
* except June with 87% for Moderna

J&J: >90%
* except June with 54%

* related to behavior? (see #1) Image
3/ COVID vaccine effectiveness vs HOSPITALIZATION:

Among 50-64 year-olds:
Pfizer/Moderna: >90%
J&J: 87-93%

STABLE OVER TIME. Image
Read 8 tweets
11 Oct
2/ WE NEED THE SERENITY TO ACCEPT THE THINGS WE CANNOT CHANGE:

COVID is here to stay.
SARS-CoV-2 cannot be eliminated.
The virus will become endemic (i.e. ongoing community transmission).
3/ ...THE COURAGE TO CHANGE THE THINGS WE CAN:

Maximize use of testing, ventilation, & air filtration.
Tailor based on individual risk.
Masks in some settings.
Support caregivers.
Paid sick leave.
Better treatment/care for long COVID patients as well as disability benefits.
Read 5 tweets
9 Oct
1/ Facebook whistleblower @FrancesHaugen joined @WSJPodcasts in Part 6 of the Facebook Files:
wsj.com/podcasts/the-j…
2/ Some highlights:

at 8:30

Vaccine disinformation is being targeted at these groups, too:

justhumanproductions.org/podcasts/s1e72…

justhumanproductions.org/podcasts/s1e74… Image
3/ at 10:50

Top 10 Facebook threats to democracy AND public health:

hate speech
misinformation
harassment
impersonation
voter suppression Image
Read 7 tweets
8 Oct
1/ New @NEJM paper from Qatar on Pfizer vaccine effectiveness vs SARS-CoV-2 infection, severe COVID, or death from COVID.

nejm.org/doi/full/10.10…
2/ The study population included Qatar *residents*.

Note that 90% of people in Qatar are economic migrants from South Asia and other countries.

🤔
3/ Vaccine effectiveness vs INFECTION:
- Peaks at 78% ~1 month after 2nd dose of Pfizer vaccine
- Declines over time
Read 10 tweets
7 Oct
1/ New @NEJM study from Israel on immunity from Pfizer vaccine out to 6+ months.
nejm.org/doi/full/10.10…

Study participants were healthcare workers at a big hospital.

They provided blood samples before getting vaccinated & then monthly x 6 months.

None had COVID prior to vaxx.
2/ Antibody responses were measured for 6 months after 2nd dose of the Pfizer vaccine.

Antibody titers were highest days 4-30 after 2nd dose.

Antibody titers dropped over time.

THIS IS TO BE EXPECTED.
3/ Not surprisingly, antibody titers started lower and dropped down lower among older persons (65+) than younger persons (<45).
Read 15 tweets
7 Oct
1/ New Israeli PRE-PRINT on the impact of Pfizer vaccine boosters:
medrxiv.org/content/10.110…

On 7/30, Israel started giving Pfizer booster doses to those 60+.

They then expanded Pfizer boosters to younger age groups:
50-59 on 8/13
40-49 on 8/20
30-39 on 8/24
16+ on 8/29
2/ It's interesting to note who got boosters and who didn't.

People who got boosters were more likely to be:
- Male
- general Jewish (vs Arab or ultra-Orthodox Jewish)
- Age 70+
3/ It takes time for the immune system to respond to vaccination.

People also behave differently immediately after vaccination than they do a couple weeks later.

So let's focus on the impact of a booster 12+ days after a booster dose.
Read 21 tweets

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