My new essay: In topics ranging from covid-19 to HIV research to the long history of wrongly assuming women’s illnesses are psychosomatic, we have seen again and again that medicine, like all science, is political.
We are not prepared for the surge in disability due to #LongCovid. The physiological damage covid causes can include cognitive dysfunction, GI immune system damage, immune dysfunction, increased risk of kidney outcomes, dysfunction in T cell memory generation, pancreas damage, 2/
We are seeing concerted efforts to downplay the long-term health effects of covid using strategies straight out of the climate change denial playbook... Many have a significant financial interest in distorting the science around long term effects of covid. 3/
In thinking of science as perfectly objective, many scientists miss their own blindspots and are vulnerable to bad-faith attacks...“We spent a long time thinking we were engaged in an argument about data & reason, but now we realize it’s a fight over money & power" 4/
There is not a clean break from the history of racism & sexism in medicine where bias was eliminated and all unknowns were solved. 5/
Medical data are filtered through the opinions of doctors, decisions of what tests to order, what types of scans to take, what guidelines recommend, what tech currently exists. And the tech that exists depends on research & funding decisions stretching back decades. 6/
Research shows that receiving a psychological misdiagnosis lengthens the time it takes to get the correct diagnosis, since many doctors will stop looking for physiological explanations. This dynamic holds true at the disease level as well. 7/
Globally, we are at a pivotal time in determining how societies & governments will deal with the influx of newly disabled people due to long covid. Narratives that take hold early often have disproportionate staying power. 8/
Please read the full article here (includes more context about the GBD, history of ACT UP, treatment of ME/CFS, and other relevant context) 9/
The human immune system is impressive, but so are the mechanisms pathogens use to evade it. In my new post, I cover 5 surprising and ingenious ways that viruses & bacteria can subvert our defenses. 1/
Our cells contain microscopic motor proteins that transport cargo along microtubules. The virus (HSV-1) that is increasingly being linked to Alzheimer's Disease uses our motor proteins to transport its viral DNA to the nucleus, so that it can start replicating faster. 2/
T cells are a crucial part of the immune system. A single-celled organism (T. cruzi, cause of Chagas disease) blocks the signal which coordinates T cell response. With no T cell response to it, T. cruzi can survive 10-30 years in a person, before wreaking havoc or death. 3/
My daughter is constantly creating– her passions include making art, writing fiction, coding interactive games, and composing music. Some might say my husband & I are terrible parents… because she does all these things on screens 1/
I am concerned by how these false interlocking points are being repeated by politicians & pundits: that screentime is very harmful for children, that it is essential for kids to attend in-person school every day (even when sick), and that workers must return to the office. 2/
Overemphasizing in-person school attendance overlooks the many kids whose needs aren’t met by in-person school. It also overlooks the many online & screen-based options opportunities to build skills, express creativity, and form friendships. 3/
There is much confusion about the "hygiene hypothesis" (what kind of microbes are beneficial vs. harmful?)-- a clearer refinement of it is the framing of "old friends" vs. "crowd infections"
Our immune systems evolved in a different world, without 100,000 flights per day 1/
Some people compare the immune system to a muscle that gets stronger with use. Yet some infections leave lasting harm. Viruses are increasingly linked with multiple sclerosis, Alzheimer's, type 1 diabetes, cancer, & more...
Allergies are a misfiring of immune system– when it attacks harmless environmental substances, e.g. pollen or dust. Autoimmunity is a different type of immune misfiring– when it attacks our own cells. Both are on the rise.
All the diseases in below chart are autoimmune. 3/
Friends with no previous interest in AI ethics have been asking me about it recently, so I want to share several underlying concepts about AI & power that are important to understand. 🧵 1/
AI and Power: The Ethical Challenges of Automation, Centralization, & Scale
In Australia, automation was used to scale putting poor people into debt (often illegally). The govt went from creating 20,000 new debts PER YEAR to creating 20,000 new debts PER WEEK, many of them bogus, but hard for people to appeal. 3/
Rheumatoid arthritis, Crohn's disease, Multiple sclerosis, Type 1 Diabetes, Lupus, Hashimoto's, & Psoriasis impact a range of body systems, but all are autoimmune diseases.
Developing a lifelong autoimmune disease is often first triggered by an infection. 2/
Medicine is very siloed, and autoimmune diseases have often been treated in separate silos, based on which body system they impact, limiting our broader understanding of common threads. 3/
Even common viruses can have long-reaching, surprising, & devastating consequences. Fortunately, there are simple steps we can take to reduce transmission. 1/
The idea that a common childhood virus can quietly hang out in your nervous system, reactivate decades later to cause shingles, and then months AFTER shingles blisters clear up cause blood clots & strokes is mind-boggling to me 2/
VZV (chickenpox virus) is not just linked to strokes, but also linked to multiple sclerosis or vascular dementia (my note: possibly through reactivating other viruses).