Yale Update (short thread)
0.15% pos.rate for students (0.17% undergrads⬆️; 0.1% grad students⬇️)
0.25% for faculty staff⬇️

Vaccination rates creep higher.

We are at VERY similar case levels to last year: why should be celebrate? Because we are MUCH closer to normal.
Last year, there were few classes held in-person and those that were held, were near empty. This year, full census in classrooms.
Last year, staff (including most/many faculty) & researchers were primarily WFH. This year, they are back to working on-site, albeit with some accommodations/modifications.
Last year, students were being tested twice weekly. This year, once weekly.
Last year, masking was required in and out of doors. This year, masking is required in MANY indoor situations, but certainly not all. ehs.yale.edu/mask-guidance
Last year, no sanctioned indoor entertainment or group meetings. This year, some limits on size, but many many events.
Last year without vaccines, Yale protected the surrounding community and our own community, but did so at great compromise to normal activities.

Vaccines have saved lives everywhere; but they are also giving us our lives back at Yale. /end

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More from @thehowie

18 Oct
Brief thread:

We have a "rheostat". It works by dialing up and down *some* de-densification, masking, TESTING, & OBVIOUSLY vaccinations, but also boosters at some point.

We can AND SHOULD dial these up when outbreaks present.
It does not mean that we can't have social events, but we need to offset this in other ways.

Wear a mask if you are speaking face to face with someone.
DO NOT hold events in poorly ventilated spaces.

Use AND advocate testing in schools and other settings where spread WILL occur.
Read 6 tweets
12 Oct
Key findings from KFF:

"...91% of Democrats, 85% of independents, and 76% of Republicans, as well as majorities of seniors (84%), who would be most affected by such a provision [favor drug price negotiations by Medicare prior to learning more]"
"...most (84%) of the public, including 3/4 (78%) of Republicans, say the argument in favor – “this is needed because Americans pay higher prices than people in other countries, many can’t afford their prescriptions, & drug company profits are too high” – is convincing."
"...a third (33%) say the argument against – “this would have the government too involved and will lead to fewer new drugs being available in the future” – is convincing. This includes nearly half (45%) of Republicans."
Read 5 tweets
20 Sep
Thread:
I've been paying more attention to the histories on emergency department (ED) patients coming in w/ covid.

They are younger. They are almost exclusively unvaccinated (the ones that are vaccinated are generally much older and/or have immune suppression).
They convey fear, frustration, & anguish. Many have already been to the ED 1 or more times. Their symptoms are often constitutional (headaches, extreme fatigue, muscle aches).
In all my time in medicine, I have not seen lingering symptoms to this degree after a viral infection (caveat, AIDS). We see the occasional post-viral/post-flu pneumonia cases; & PCPs have seen many weakened or exhausted by bad flu; but numbers that present to the ED are large.
Read 6 tweets
9 Sep
Florida with 1,296 newly reported deaths today! (NOT a record, but likely muted by Labor Day Holiday).

Will continue in this thread with further points of note from this CDC report. Follow along if interested.
We have a new single day record for deaths (and this is far from a final number so expect it to be substantially higher when all deaths are reported)

330 on August 20th
I have expected that the peak would occur in the week following August 20th, so not only is 330 far from a complete figure but it will not be the final peak. Would now predict absolute peak >350 or so.
Read 5 tweets
1 Sep
The implications for this are vast & ANOTHER reason why we need timely, responsive clinical trials funded & supported by government. (cc:@ScottGottliebMD )

Bottom line: we don't know enough about protective immunity conferred by prior infection.

brief additional thoughts: Image
(And one could extend this to vaccinated individuals, but here we have clinical trials funded by the vaccine manufacturers that can answer most of these questions).
A LARGE percent of DOCUMENTED previously infected individuals do not have measurable antibodies. This does not mean they are not protected. But it sure raises questions.
Read 7 tweets
28 Aug
A lot of widely spread misinformation out there.

Here are facts as we know them today.

1. Vaccines reduce spread. Far less than we would have hoped but still substantially. They are still EXTREMELY effective against severe illness & death.
2. Vaccinated individuals do NOT spread more than unvaccinated individuals.

3. The CDC director does NOT believe that vaccines do not reduce transmission.
4. Ivermectin works well for strongyloidiasis & onchocerciasis. It has no proven use in preventing or treating COVID. In some forms, it can be dangerous, however.
Read 8 tweets

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